PIMA527256

MED28 Monoclonal Antibody (OTI10C8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527256-Each-of-1 In Stock ₹ 50,180.94

PIMA527256 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

MED28

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9H204

Gene Symbols

MED28

Immunogen

Full length human recombinant protein of MED28 produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI10C8

Conjugate

Unconjugated

Gene

MED28

Gene Alias

1500003D12Rik; AI451633; AU045690; EG1; endothelial-derived; endothelial-derived gene 1; endothelial-derived protein 1; Fksg20; Magicin; Med28; Mediator complex subunit 28; mediator of RNA polymerase II transcription subunit 28; mediator of RNA polymerase II transcription, subunit 28 homolog; merlin and Grb2-interacting cytoskeletal protein; RGD1305875; Tumor angiogenesis marker EG-1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

80306

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The mediator complex is a multi-protein transcriptional co-activator that is expressed ubiquitously in eukaryotes from yeast to mammals and is required for induction of RNA polymerase II (pol II) transcription by DNA binding transcription factor
  • One of the proteins in this complex is MED28, also known as Magicin
  • MED28 is expressed in many cell lines and tissues
  • It has been shown that a down-regulation of MED28 expression in NIH3T3 cells results in a significant induction of several genes associated with smooth muscle cell differentiation and conversely its over-expression represses expression of SMC genes
  • MED28 can also form a ternary complex with Grb2 and Merlin, the neurofibromatosis 2 tumor suppressor protein, indicating that MED28 may play a role in Merlin's tumor suppressive activity
  • MED28 has also been recently identified as an HIV dependency factor (HDF), suggesting that MED28 may be an important drug target in HIV treatment
  • At least two isoforms of MED28 are known to exist.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA527256

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Antigen:
MED28

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H204

Gene Symbols:
MED28

Immunogen:
Full length human recombinant protein of MED28 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI10C8

Conjugate:
Unconjugated

Gene:
MED28

Gene Alias:
1500003D12Rik; AI451633; AU045690; EG1; endothelial-derived; endothelial-derived gene 1; endothelial-derived protein 1; Fksg20; Magicin; Med28; Mediator complex subunit 28; mediator of RNA polymerase II transcription subunit 28; mediator of RNA polymerase II transcription, subunit 28 homolog; merlin and Grb2-interacting cytoskeletal protein; RGD1305875; Tumor angiogenesis marker EG-1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80306

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA527258

--


Antigen:
SEC23B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q15437

Gene Symbols:
SEC23B

Immunogen:
Human recombinant protein fragment corresponding to amino acids 392-641 of SEC23B produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI6E8

Conjugate:
Unconjugated

Gene:
SEC23B

Gene Alias:
CDAII; CDA-II; CDAN2; CWS7; HEMPAS; hSec23B; Protein transport protein Sec23B; Sec23 homolog B; Sec23 homolog B (S. cerevisiae); Sec23 homolog B, coat complex II component; Sec23 homolog B, COPII coat complex component; Sec23b; SEC23B (S. cerevisiae); SEC23-like protein B; SEC23-related protein B; transport protein SEC23B

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10483

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA527259

--


Antigen:
BHLHE40

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O14503

Gene Symbols:
BHLHE40

Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-313 of BHLHE40 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI4C4

Conjugate:
Unconjugated

Gene:
BHLHE40

Gene Alias:
1-Dec; basic helix-loop-helix domain containing, class B, 2; basic helix-loop-helix domain containing, class B2; basic helix-loop-helix family member e40; basic helix-loop-helix family, member e40; bHLHb2; Bhlhe40; C130042M06Rik; Class B basic helix-loop-helix protein 2; class E basic helix-loop-helix protein 40; Clast5; CR8; cytokine response gene 8; DEC1; differentially expressed in chondrocytes 1; differentially expressed in chondrocytes protein 1; differentiated embryo chondrocyte expressed gene 1; E47 interaction protein 1; EIP1; eip1 (E47 interaction protein 1); enhancer-of split and hairy-related protein 2; enhancer-of-split and hairy-related protein 2; FLJ99214; HLHB2; SHARP2; SHARP-2; stimulated by retinoic acid 14; stimulated by retinoic acid gene 13 protein; STRA13; Stra14

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8553

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA527262

--


Antigen:
SEC23B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q15437

Gene Symbols:
SEC23B

Immunogen:
Human recombinant protein fragment corresponding to amino acids 392-641 of SEC23B produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI8G4

Conjugate:
Unconjugated

Gene:
SEC23B

Gene Alias:
CDAII; CDA-II; CDAN2; CWS7; HEMPAS; hSec23B; Protein transport protein Sec23B; Sec23 homolog B; Sec23 homolog B (S. cerevisiae); Sec23 homolog B, coat complex II component; Sec23 homolog B, COPII coat complex component; Sec23b; SEC23B (S. cerevisiae); SEC23-like protein B; SEC23-related protein B; transport protein SEC23B

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10483

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid