PIMA527491

RGMA Monoclonal Antibody (OTI4G8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527491-Each-of-1 In Stock ₹ 50,180.94

PIMA527491 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

RGMA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q96B86

Gene Symbols

RGMA

Immunogen

Human recombinant protein fragment corresponding to amino acids 169-424 of RGMA produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunohistochemistry (Paraffin)

Clone

OTI4G8

Conjugate

Unconjugated

Gene

RGMA

Gene Alias

BC059072; C230063O06; repulsive guidance molecule; repulsive guidance molecule A; repulsive guidance molecule family member a; RGM; RGM domain family member A; RGM domain family, member A; RGMA

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56963

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system
  • Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses
  • Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition
  • Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway
  • It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA527491

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Antigen:
RGMA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q96B86

Gene Symbols:
RGMA

Immunogen:
Human recombinant protein fragment corresponding to amino acids 169-424 of RGMA produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Paraffin)

Clone:
OTI4G8

Conjugate:
Unconjugated

Gene:
RGMA

Gene Alias:
BC059072; C230063O06; repulsive guidance molecule; repulsive guidance molecule A; repulsive guidance molecule family member a; RGM; RGM domain family member A; RGM domain family, member A; RGMA

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56963

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA527493

--


Antigen:
REV1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9UBZ9

Gene Symbols:
Rev1

Immunogen:
Human recombinant protein fragment corresponding to amino acids 1079-1251 of REV1 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1E12

Conjugate:
Unconjugated

Gene:
Rev1

Gene Alias:
1110027I23Rik; AIBP80; alpha integrin-binding protein 80; AU022044; DNA repair protein REV1; REV1; REV1 homolog; REV1 homolog (S. cerevisiae); REV1- like; REV1, DNA directed polymerase; REV1, polymerase (DNA directed); REV1L; rev1-like terminal deoxycytidyl transferase

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
316344, 51455

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA527496

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Antigen:
SH3BP1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9Y3L3

Gene Symbols:
SH3BP1

Immunogen:
Full length human recombinant protein of SH3BP1 produced in HEK293T cell

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI1C9

Conjugate:
Unconjugated

Gene:
SH3BP1

Gene Alias:
3bp1; 3BP-1; ARHGAP43; OTTHUMP00000028981; SH3 domain binding protein 1; SH3 domain-binding protein 1; SH3BP1; SH3-domain binding protein 1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23616

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA527497

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Antigen:
ALS2CR11

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q53TS8

Gene Symbols:
C2CD6

Immunogen:
Human recombinant protein fragment corresponding to amino acids 307-623 of ALS2CR11 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI7A8

Conjugate:
Unconjugated

Gene:
C2CD6

Gene Alias:
1700052H20Rik; 4930408G06Rik; Als2cr11; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 (human); amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein; amyotrophic lateral sclerosis 2 chromosome region candidate 11; C2 calcium-dependent domain-containing protein 6; C2CD6; testicular tissue protein Li 16

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
151254

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid