PIMA527500

SHARPIN Monoclonal Antibody (OTI1F4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527500-Each-of-1 In Stock ₹ 53,047.20

PIMA527500 - Each of 1

₹ 53,047.20

In Stock

Quantity

1

Base Price: ₹ 53,047.20

GST (18%): ₹ 9,548.496

Total Price: ₹ 62,595.696

Antigen

SHARPIN

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9H0F6

Gene Symbols

SHARPIN

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-326 of SHARPIN produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

OTI1F4

Conjugate

Unconjugated

Gene

SHARPIN

Gene Alias

0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

81858

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA526852

--

Img

Thermo Scientific

PIMA527310

--

Img

Thermo Scientific

PIMA527224

--

Img

Thermo Scientific

PIMA527099

--

Img

Thermo Scientific

PIMA527289

--

Img

Thermo Scientific

PIMA526998

--

Img

Thermo Scientific

PIMA527201

--

Img

Thermo Scientific

PIMA527016

--

Description

  • Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation
  • LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways
  • Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation
  • LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex
  • Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA527500

--


Antigen:
SHARPIN

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H0F6

Gene Symbols:
SHARPIN

Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-326 of SHARPIN produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
OTI1F4

Conjugate:
Unconjugated

Gene:
SHARPIN

Gene Alias:
0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
81858

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA527502

--


Antigen:
IFITM2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q01629

Gene Symbols:
IFITM2

Immunogen:
Full length human recombinant protein of IFITM2 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI2B3

Conjugate:
Unconjugated

Gene:
IFITM2

Gene Alias:
1-8D; dispanin subfamily A member 2c; DSPA2c; IFITM2; ifm2; interferon induced transmembrane protein 2; interferon-induced transmembrane protein 2; Interferon-inducible protein 1-8D

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10581

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA527504

--


Antigen:
IFITM2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q01629

Gene Symbols:
IFITM2

Immunogen:
Full length human recombinant protein of IFITM2 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI4E3

Conjugate:
Unconjugated

Gene:
IFITM2

Gene Alias:
1-8D; dispanin subfamily A member 2c; DSPA2c; IFITM2; ifm2; interferon induced transmembrane protein 2; interferon-induced transmembrane protein 2; Interferon-inducible protein 1-8D

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10581

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA527505

--


Antigen:
OXPAT

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q00G26

Gene Symbols:
Plin5

Immunogen:
Human recombinant protein fragment corresponding to amino acids 1-463 of PLIN5 produced in E.coli

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
OTI3F2

Conjugate:
Unconjugated

Gene:
Plin5

Gene Alias:
2310076L09Rik; AI415325; AW109675; lipid droplet associated protein; lipid droplet-associated protein PAT-1; Lipid storage droplet protein 5; LSDA5; LSDP5; Mldp; Myocardial LD protein; Oxpat; Pat1; PAT-1; perilipin 5; perilipin-5; Plin5

Host Species:
Mouse

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
440503

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid