PIMA527676

KCNQ1 Monoclonal Antibody (N37A/10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527676-Each-of-1 In Stock ₹ 50,608.74

PIMA527676 - Each of 1

₹ 50,608.74

In Stock

Quantity

1

Base Price: ₹ 50,608.74

GST (18%): ₹ 9,109.573

Total Price: ₹ 59,718.313

Antigen

KCNQ1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

P51787, P97414, Q9Z0N7

Gene Symbols

KCNQ1

Immunogen

Fusion protein amino acids 2-101 of human KCNQ1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Hamster, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

N37A/10

Conjugate

Unconjugated

Gene

KCNQ1

Gene Alias

ATFB1; ATFB3; AW559127; FLJ26167; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; JLNS1; KCNA8; KCNA9; Kcnq1; kidney and cardiac voltage dependend K+ channel; KQT-like 1; Kv1.9; Kv7.1; KVLQT1; LQT; LQT1; mutant potassium voltage-gated channel KQT-like subfamily member 1; potassium channel, voltage gated KQT-like subfamily Q, member 1; potassium channel, voltage-gated KQT-like subfamily Q, member 1; potassium voltage-gated channel subfamily KQT member 1; potassium voltage-gated channel subfamily Q member 1; potassium voltage-gated channel, KQT-like subfamily, member 1; potassium voltage-gated channel, subfamily Q, member 1; RWS; slow delayed rectifier channel subunit; SQT2; voltage-gated potassium channel subunit Kv7.1; WRS

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

100761481, 16535, 3784, 84020

Content And Storage

-20°C

Form

Liquid

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Description

  • 1 μg/mL of MA5-27676 was sufficient for detection of KCNQ1 in 10 μg of COS-1 cell lysate transiently expressing KCNQ1 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 75kDa
  • Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells
  • A specific K+ channel, comprised of an alpha subunit KCNQ1 and a beta subunit KCNE1, a small protein which spans the membrane only once, is predominantly expressed in the heart and in the cochlea, and is responsible for regulating the slow, depolarization-activated potassium current
  • Mutations in the genes encoding for KCNQ1 and KCNE1 lead to cardiac disease because they directly impair electrical signaling, and mutations in KCNQ4 are implicated in the onset of deafness
  • KCNQ proteins, including KCNQ1 and KCNQ4, characteristically contain six transmembrane domains and function as tetramers
  • KCNQ4 forms heteromeric channels with KCNQ3 and is expressed in several tissues, including the cochlea, where it is present in outer hair cells.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA527676

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Antigen:
KCNQ1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P51787, P97414, Q9Z0N7

Gene Symbols:
KCNQ1

Immunogen:
Fusion protein amino acids 2-101 of human KCNQ1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
N37A/10

Conjugate:
Unconjugated

Gene:
KCNQ1

Gene Alias:
ATFB1; ATFB3; AW559127; FLJ26167; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; JLNS1; KCNA8; KCNA9; Kcnq1; kidney and cardiac voltage dependend K+ channel; KQT-like 1; Kv1.9; Kv7.1; KVLQT1; LQT; LQT1; mutant potassium voltage-gated channel KQT-like subfamily member 1; potassium channel, voltage gated KQT-like subfamily Q, member 1; potassium channel, voltage-gated KQT-like subfamily Q, member 1; potassium voltage-gated channel subfamily KQT member 1; potassium voltage-gated channel subfamily Q member 1; potassium voltage-gated channel, KQT-like subfamily, member 1; potassium voltage-gated channel, subfamily Q, member 1; RWS; slow delayed rectifier channel subunit; SQT2; voltage-gated potassium channel subunit Kv7.1; WRS

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100761481, 16535, 3784, 84020

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527679

--


Antigen:
Kir6.1 (KCNJ8)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
P97794, Q15842, Q63664

Gene Symbols:
KCNJ8

Immunogen:
Fusion protein amino acids 306-424 (Cytoplasmic C-terminus) of rat Kir6.1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
S366-60

Conjugate:
Unconjugated

Gene:
KCNJ8

Gene Alias:
AI448900; ATP-sensitive inward rectifier potassium channel 8; ATP-sensitive inward rectifier potassium channel Kir6.1; gnite; Inward rectifier K(+) channel Kir6.1; inward rectifier potassium channel 6.1; inward rectifier potassium channel Kir6.1; inwardly rectifier K(+) channel Kir6.1; Inwardly rectifying potassium channel gene subfamily J-8 (ATP sensitive); Inwardly rectifying potassium channel gene, subfamily J-8 (ATP sensitive); inwardly rectifying potassium channel Kir6.1; ion channel; Kcnj8; KCNJ8 protein; Kir6.1; Kir6.1 like; potassium channel, inwardly rectifying subfamily J member 8; potassium channel, inwardly rectifying subfamily J, member 8; potassium inwardly rectifying channel subfamily J member 8; potassium inwardly-rectifying channel J8; potassium inwardly-rectifying channel, subfamily J, member 8; potassium voltage-gated channel subfamily J member 8; si:dkey-183c2.2; slmbr; sltr; UKATP1; uKATP-1; zkir6.1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16523, 25472, 3764

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527681

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Antigen:
Kir2.1 (KCNJ2)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P35561, P63252, P63253, Q64273

Gene Symbols:
Kcnj2

Immunogen:
Fusion protein amino acids 41-64 and 189-428 of mouse Kir2.1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG1

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
S112

Conjugate:
Unconjugated

Gene:
Kcnj2

Gene Alias:
ATFB9; cardiac inward rectifier KIR2.1; cardiac inward rectifier potassium channel; EGK_08925; HHBIRK1; HHIRK 1; HHIRK1; HIRK 1; hIRK1; Inward rectifier K; inward rectifier K(+) channel Kir2.1; inward rectifier K+ channel KIR2.1; inward rectifier potassium channel; inward rectifier potassium channel 2; inwardly rectifying potassium channel Kir2.1; IRK 1; IRK1; IRK-1; IRK2; Kcnf1; KCNJ2; KIR2.1; LQT 7; LQT7; Potassium channel, inwardly rectifying subfamily J member 2; potassium channel, inwardly rectifying subfamily J, member 2; potassium inwardly rectifying channel subfamily J member 2; potassium inwardly-rectifying channel, subfamily J, member 2; potassium voltage-gated channel subfamily J member 2; RBL-IRK1; SQT 3; SQT3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16518, 29712, 3759, 574189

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527682

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Antigen:
KV3.4 (KCNC4)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q03721, Q63734, Q8R1C0

Gene Symbols:
KCNC4

Immunogen:
Synthetic peptide amino acids 175-192 of rat Kv3.4

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
S72-16

Conjugate:
Unconjugated

Gene:
KCNC4

Gene Alias:
AI850292; C1orf30; HKSHIIIC; K+ channel subunit; KCNC4; Kcr2-4; KSHIIIC; Kv3.4; MGC126818; potassium channel, voltage gated Shaw related subfamily C, member 4; potassium channel, voltage gated Shaw-related subfamily C, member 4; potassium voltage gated channel, Shaw-related subfamily, member 4; potassium voltage-gated channel subfamily C member 4; potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (Raw3); potassium voltage-gated channel, Shaw-related subfamily, member 4; raw3; Voltage-gated potassium channel subunit Kv3.4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3749, 684516, 99738

Content And Storage:
-20°C

Form:
Liquid