PIMA527720

ATP7A Monoclonal Antibody (S60-4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527720-Each-of-1 In Stock ₹ 50,523.18

PIMA527720 - Each of 1

₹ 50,523.18

In Stock

Quantity

1

Base Price: ₹ 50,523.18

GST (18%): ₹ 9,094.172

Total Price: ₹ 59,617.352

Antigen

ATP7A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

P70705, Q04656, Q64430

Gene Symbols

ATP7A

Immunogen

Synthetic peptide amino acids 42-61 (cytoplasmic C-terminus) of human Copper- transporting ATPase1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG2b

Applications

Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Clone

S60-4

Conjugate

Unconjugated

Gene

ATP7A

Gene Alias

ATP 7A; ATP7A; ATPase copper transporting alpha; ATPase, Cu++ transporting, alpha polypeptide; copper pump 1; Copper-transporting ATPase 1; Cu++-transporting P-type ATPase; DSMAX; FLJ17790; MC 1; MC1; Menke; Menkes disease-associated protein; menkes disease-associated protein homolog; Menkes protein; Menkes syndrome; MK; MNK; OHS; OTTHUMP00000062077; SMAX3

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

11977, 24941, 538

Content And Storage

-20°C

Form

Liquid

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Description

  • 1 μg/mL of MA5-27720 was sufficient for detection of Copper-transporting ATPase1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat IgG:HRP as the secondary antibody.∣Detects approximately 180kDa in rat brain membrane preparations
  • ATP7A (also known as Copper-transporting ATPase 1) functions as a transmembrane copper-translocating P-type ATPase and plays a vital role in systemic copper absorption in the gut and copper reabsorption in the kidney
  • Polarized epithelial cells such as Madin-Darby canine kidney cells are a physiologically relevant model for systemic copper absorption and reabsorption in vivo
  • Although ATP7A is not detectable in most normal tissues, it is expressed in a considerable fraction of many common tumor types
  • Increased expression of ATP7A renders cells resistant to cisplatin and carboplatin
  • Mutations in the ATP7A gene result in Menkes disease, which is fatal in early childhood.

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Thermo Scientific

PIMA527720

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Antigen:
ATP7A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P70705, Q04656, Q64430

Gene Symbols:
ATP7A

Immunogen:
Synthetic peptide amino acids 42-61 (cytoplasmic C-terminus) of human Copper- transporting ATPase1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Clone:
S60-4

Conjugate:
Unconjugated

Gene:
ATP7A

Gene Alias:
ATP 7A; ATP7A; ATPase copper transporting alpha; ATPase, Cu++ transporting, alpha polypeptide; copper pump 1; Copper-transporting ATPase 1; Cu++-transporting P-type ATPase; DSMAX; FLJ17790; MC 1; MC1; Menke; Menkes disease-associated protein; menkes disease-associated protein homolog; Menkes protein; Menkes syndrome; MK; MNK; OHS; OTTHUMP00000062077; SMAX3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11977, 24941, 538

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527721

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Antigen:
ATF4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
P18848, Q06507, Q9ES19

Gene Symbols:
Atf4

Immunogen:
Fusion protein amino acids 25-327 of human ATF4. 86% identical to rat, and 85% identical to mouse. <50% identity with ATF5.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
S360A-24

Conjugate:
Unconjugated

Gene:
Atf4

Gene Alias:
Activating transcription factor 4; activating transcription factor 4 (tax-responsive enhancer element B67); activating transcription factor 4a; activating transcription factor 4b1 (tax-responsive enhancer element B67); activating transcription factor ATF-4; ATF 4; atf4; Atf-4; atf4 {ECO:0000312; ATF4 protein; atf4a; atf4b1; C/ATF; C/EBP-related ATF; cAMP response element-binding protein 2; cAMP-dependent transcription factor ATF-4; cAMP-responsive element-binding protein 2; CREB 2; CREB2; CREB-2; Cyclic AMP-dependent transcription factor ATF-4; cyclic AMP-responsive element-binding protein 2; DNA-binding protein TAXREB67; hypothetical protein LOC509107; OTTHUMP00000199130; rATF-4; RGD:621863}; tax-re; TaxREB67; TaxREB67 homolog; tax-responsive enhancer element B67; tax-responsive enhancer element-binding protein 67; Tax-responsive enhancer element-binding protein 67 homolog; TXREB; wu:fj01c08; wu:fk30b04; zgc:85951

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11911, 468, 79255

Content And Storage:
-20°C

Form:
Liquid

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PIMA527722

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Antigen:
Pan Ankyrin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
G5E8K5, O70511, P16157, Q01484, Q02357, Q12955, Q8C8R3

Gene Symbols:
Ank1, Ank2, Ank3

Immunogen:
Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
S388A-60

Conjugate:
Unconjugated

Gene:
Ank1

Gene Alias:
2900054D09Rik; AI314020; AI835472; ANK; ANK1; Ank-1; ANK2; Ank-2; Ank3; ANK-3; AnkB; AnkG; ankyrin 1; ankyrin 1, erythrocytic; ankyrin 1, erythroid; ankyrin 2, brain; ankyrin 2, neuronal; ankyrin 3 (G); ankyrin 3, epithelial; ankyrin 3, node of Ranvier (ankyrin G); ankyrin B; ankyrin, brain; ankyrin-1; Ankyrin-2; ankyrin-2, nonerythrocytic; ankyrin-3; Ankyrin-B; ankyrin-G; Ankyrin-R; AW491075; Brain ankyrin; brain-specific ankyrin-G; brank-2; Erythrocyte ankyrin; LQT4; MRT37; nb; non-erythroid ankyrin; normoblastic anemia; pale; rCG_43073; SPH1; SPH2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
109676, 11733, 11735, 286, 287, 288, 306570, 361833, 362036

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527723

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Antigen:
Ankyrin 1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
P16157, Q02357

Gene Symbols:
ANK1

Immunogen:
Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
S388A-10

Conjugate:
Unconjugated

Gene:
ANK1

Gene Alias:
ANK; ANK1; ANK-1; ANK-1; erythrocyte skeletal protein; ankyrin 1; ankyrin 1, erythrocytic; ankyrin 1, erythroid; ankyrin-1; Ankyrin-R; erythrocyte ankyrin; nb; normoblastic anemia; pale; rCG_43073; SPH1; SPH2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11733, 286, 306570

Content And Storage:
-20°C

Form:
Liquid