PIMA527838

TET2 Monoclonal Antibody (GT649), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527838-Each-of-1 In Stock ₹ 48,726.42

PIMA527838 - Each of 1

₹ 48,726.42

In Stock

Quantity

1

Base Price: ₹ 48,726.42

GST (18%): ₹ 8,770.756

Total Price: ₹ 57,497.176

Antigen

TET2

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q6N021

Gene Symbols

TET2

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human TET2. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ChIP Assay, Immunoprecipitation, Western Blot

Clone

GT649

Conjugate

Unconjugated

Gene

TET2

Gene Alias

Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; TET2

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

54790

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Positive Control: 293T, A431, HeLa, HepG2 Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • TET2 is a dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydromethylcytosine (5hmC) and plays a key role in active DNA demethylation
  • TET2 has a preference for 5-hydroxymethylcytosine in CpG motifs
  • It mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC) and conversion of 5fC to 5-carboyxlcytosine (5caC)
  • Conversion of 5mC into 5hmC, 5fC, and 5caC probably constitutes the first step in cytonsine demethylation
  • In addition to TET2’s role in DNA demethylation, it is also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT
  • Mutations in the genes can result in Polycythemia vera and Myelodysplastic syndrome.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA527838

--


Antigen:
TET2

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q6N021

Gene Symbols:
TET2

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human TET2. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ChIP Assay, Immunoprecipitation, Western Blot

Clone:
GT649

Conjugate:
Unconjugated

Gene:
TET2

Gene Alias:
Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; TET2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
54790

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

PIMA527841

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Antigen:
MTPAP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and no preservative; pH 7

Gene Accession No.:
Q9NVV4

Gene Symbols:
MTPAP

Immunogen:
Human mtPAP

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
1D3

Conjugate:
Unconjugated

Gene:
MTPAP

Gene Alias:
FLJ10486; mitochondrial poly(A) polymerase; mtPAP; PAP; PAP-associated domain-containing protein 1; PAPD1; Poly(A) RNA polymerase, mitochondrial; polynucleotide adenylyltransferase; RP11305E6.3; RP11-305E6.3; SPAX4; terminal uridylyltransferase 1; TUTase 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
55149

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

PIMA527843

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Antigen:
ENY2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9NPA8

Gene Symbols:
ENY2

Immunogen:
Recombinant protein encompassing a sequence within the center region of human ENY2. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
GT245

Conjugate:
Unconjugated

Gene:
ENY2

Gene Alias:
1810057B09Rik; 6720481I12; DC6; e(y)2; e(y)2 homolog; e(y)2 protein; enhancer of yellow 2 homolog; enhancer of yellow 2 homolog (Drosophila); enhancer of yellow 2 transcription factor homolog; enhancer of yellow eye homolog; ENY 2; ENY2; ENY-2; ENY2, transcription and export complex 2 subunit; Ey2; Sus1; transcription and mRNA export factor ENY2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
56943, 685258

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA527844

--


Antigen:
KIAA1530

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q2YD98

Gene Symbols:
UVSSA

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human UVSSA. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Western Blot

Clone:
GT816

Conjugate:
Unconjugated

Gene:
UVSSA

Gene Alias:
KIAA1530; UV stimulated scaffold protein A; UVSS3; UVSSA; UV-stimulated scaffold protein A

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
57654

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid