PIMA527890

Aurora B Recombinant Rabbit Monoclonal Antibody (RM278), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527890-Each-of-1 In Stock ₹ 52,106.04

PIMA527890 - Each of 1

₹ 52,106.04

In Stock

Quantity

1

Base Price: ₹ 52,106.04

GST (18%): ₹ 9,379.087

Total Price: ₹ 61,485.127

Antigen

Aurora B

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.

O70126, Q96GD4

Gene Symbols

AURKB

Immunogen

A peptide corresponding to the N-terminus of human Aurora kinase B

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

RM278

Conjugate

Unconjugated

Gene

AURKB

Gene Alias

Aik2; AIM1; AIM-1; AIRK2; AL022959; ARK2; ARK-2; AurB; AURKB; aurkb-sv1; aurkb-sv2; aurora 1; aurora- and IPL1-like midbody-associated protein 1; aurora B; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; IPL1; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; serine/threonine-protein kinase aurora-B; STK1; STK-1; Stk12; STK12; AIK2; AIM1; ARK2; IPL1; AIM-1; STK5

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

20877, 9212

Content And Storage

-20°C

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • The Aurora kinases associate with microtubules during chromosome movement and segregation
  • AURKB (Aurora B) localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers
  • This complex functions in chromosome alignment and separation, histone modification, and cytokinesis
  • CPC also includes three non-enzymatic subunits known as the inner centromere protein (INCENP), survivin, and borealin, which determine the activity, localization, stability, and possibly even the substrate specificity of AurB
  • Two CPCs exist during mitosis: one containing all four members and another consisting of INCENP and AurB
  • Quaternary CPC functions during chromosome alignment and cytokinesis, whereas the INCENP-AurB complex may be responsible for modifying histone H3
  • AurB is overexpressed in a number of tumours, including primary breast and colon tumour samples
  • Its expression in tumours seems to be linked with Aurora-A kinase, suggesting a feedback mechanism between the two proteins.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA527890

--


Antigen:
Aurora B

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
O70126, Q96GD4

Gene Symbols:
AURKB

Immunogen:
A peptide corresponding to the N-terminus of human Aurora kinase B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
RM278

Conjugate:
Unconjugated

Gene:
AURKB

Gene Alias:
Aik2; AIM1; AIM-1; AIRK2; AL022959; ARK2; ARK-2; AurB; AURKB; aurkb-sv1; aurkb-sv2; aurora 1; aurora- and IPL1-like midbody-associated protein 1; aurora B; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; IPL1; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; serine/threonine-protein kinase aurora-B; STK1; STK-1; Stk12; STK12; AIK2; AIM1; ARK2; IPL1; AIM-1; STK5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20877, 9212

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527891

--


Antigen:
BAG1L

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
Q99933

Gene Symbols:
BAG1

Immunogen:
A peptide corresponding to residues near the N-terminus of human BAG-1L

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
RM310

Conjugate:
Unconjugated

Gene:
BAG1

Gene Alias:
BAG family molecular chaperone regulator 1; BAG1; BAG-1; BCL2 associated athanogene 1; Bcl-2 associating athanogene-1 protein; BCL2-associated athanogene; Bcl-2-associated athanogene 1; Bcl-2-binding protein; glucocortoid receptor-associated protein RAP46; HAP; RAP46; receptor-associated protein, 46-KD

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
573

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527892

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Antigen:
Calponin 1

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P51911, Q08091

Gene Symbols:
CNN1

Immunogen:
A peptide corresponding to the C-terminus of human Calponin-1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
RM262

Conjugate:
Unconjugated

Gene:
CNN1

Gene Alias:
Basic calponin; calponin; calponin 1; calponin 1, basic, smooth muscle; calponin 1, smooth muscle; calponin H1, smooth muscle; Calponin-1; calponins, basic; CN; CNN1; CnnI; epididymis secretory protein Li 14; h1-calponin; HEL-S-14; similar to calponin 1, basic, smooth muscle; Sm-Calp; SMCC; smooth muscle calponin h1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1264, 12797

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527895

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Antigen:
OX40 (CD134)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P43489

Gene Symbols:
Tnfrsf4

Immunogen:
A peptide corresponding to the C-terminus of human OX40 (CD134)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM313

Conjugate:
Unconjugated

Gene:
Tnfrsf4

Gene Alias:
ACT35; ACT35 antigen; ATC35 antigen; CD134; CD134 antigen; IMD16; Ly-70; lymphoid activation antigene ACT35; MRC OX40; Ox40; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 receptor; TNF receptor superfamily member 4; Tnfrsf4; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily, member 4; tumor necrosis factor superfamily, member 4; Txgp1; Txgp1l

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7293

Content And Storage:
-20°C

Form:
Liquid