PIMA527973

p27Kip1 Recombinant Rabbit Monoclonal Antibody (RM302), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527973-Each-of-1 In Stock ₹ 47,956.38

PIMA527973 - Each of 1

₹ 47,956.38

In Stock

Quantity

1

Base Price: ₹ 47,956.38

GST (18%): ₹ 8,632.148

Total Price: ₹ 56,588.528

Antigen

p27Kip1

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.

P46414, P46527

Gene Symbols

Cdkn1b

Immunogen

A peptide corresponding to the C-terminus of human p27Kip1

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

RM302

Conjugate

Unconjugated

Gene

Cdkn1b

Gene Alias

AA408329; AI843786; Cdki1b; CDKN1B; CDKN4; CDN1B; cyclin dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor 1B (p27 Kip1); Cyclin-dependent kinase inhibitor 1B (p27, Kip1); cyclin-dependent kinase inhibitor p27; Cyclin-dependent kinase inhibitor p27 Kip1; cyclin-dependent kinase inhibitor p27/Kip1; KIP1; MEN1B; MEN4; p27; P27 CDKN1B; p27(KIP1); p27Kip1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1027, 12576

Content And Storage

-20°C

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • p27 Kip1 functions as a negative regulator of G1 mouse expression and has been proposed to function as a possible mediator of TGFb induced G1 arrest
  • p27 Kip1 is an important regulator of cell cycle progression, a potent inhibitor of cyclin E- and cyclin A-CDK2 complexes
  • p27 Kip1 forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation
  • p27 Kip1 acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry
  • p27 Kip1 has a molecular weight of approximately 27kDa and the degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA527973

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Antigen:
p27Kip1

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P46414, P46527

Gene Symbols:
Cdkn1b

Immunogen:
A peptide corresponding to the C-terminus of human p27Kip1

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM302

Conjugate:
Unconjugated

Gene:
Cdkn1b

Gene Alias:
AA408329; AI843786; Cdki1b; CDKN1B; CDKN4; CDN1B; cyclin dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor 1B (p27 Kip1); Cyclin-dependent kinase inhibitor 1B (p27, Kip1); cyclin-dependent kinase inhibitor p27; Cyclin-dependent kinase inhibitor p27 Kip1; cyclin-dependent kinase inhibitor p27/Kip1; KIP1; MEN1B; MEN4; p27; P27 CDKN1B; p27(KIP1); p27Kip1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1027, 12576

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527976

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Antigen:
Phosphothreonine

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Mixture of phosphothreonine-BSA conjugate and a phosphothreonine containing peptide

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
RM102

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
C4H10NO6P; O-phospho-L-threonine; Phospho-threonine; pThr; Threonine

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527977

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Antigen:
Phosphotyrosine

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Phosphotyrosine-BSA conjugate

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation

Clone:
RM111

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Phosphotyrosine; pTyr; pY

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527982

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Antigen:
Phospho-NDRG1 (Thr346)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q62433, Q92597

Gene Symbols:
NDRG1

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr346 of human phospho NDRG1.

Quantity:
200μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry, Western Blot

Clone:
NDRG1T346-F5

Conjugate:
Unconjugated

Gene:
NDRG1

Gene Alias:
CAP43; CMT4D; differentiation-related gene 1 protein; DRG1; DRG-1; GC4; HMSNL; Ndr1; Ndrg1; Ndrl; nickel-specific induction protein Cap43; NMSL; N-myc downstream regulated 1; N-myc downstream regulated gene 1; N-myc downstream-regulated gene 1 protein; Protein Ndr1; protein NDRG1; protein regulated by oxygen-1; PROXY1; Reducing agents and tunicamycin-responsive protein; Rit42; RTP; TARG1; TDD5

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
10397, 17988

Content And Storage:
-20°C

Form:
Liquid