PIMA528034

Phospho-PLCg2 (Tyr759) Recombinant Rabbit Monoclonal Antibody (PLCG2Y759-G3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA528034-Each-of-1 In Stock ₹ 47,956.38

PIMA528034 - Each of 1

₹ 47,956.38

In Stock

Quantity

1

Base Price: ₹ 47,956.38

GST (18%): ₹ 8,632.148

Total Price: ₹ 56,588.528

Antigen

Phospho-PLCg2 (Tyr759)

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P16885, Q8CIH5

Gene Symbols

Plcg2

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr759 of human phospho PLCgamma2.

Quantity

200μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG κ

Applications

Flow Cytometry, Western Blot

Clone

PLCG2Y759-G3

Conjugate

Unconjugated

Gene

Plcg2

Gene Alias

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

234779, 5336

Content And Storage

-20°C

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate
  • There are many mammalian PLC isozymes, including PLC beta1, PLC beta2, PLC beta3, PLC beta4, PLC gamma1, PLC gamma2, PLC delta1, PLC delta2 and PLCe
  • PLC delta exists as four different isoforms
  • PLC delta1, a calcium signal amplifier, is activated by an atypical GTP-binding protein
  • In addition, PLC delta1 is an effector for GTP-binding protein transglutaminase II-mediated oxytocin receptor and alpha1B-adrenoreceptor signaling
  • Mouse PLC delta1 is highly expressed in brain, heart, lung and testis
  • PLC delta is abnormally accumulated in autopsied brains with Alzheimer's disease (AD), suggesting that it may play a role in the pathology of AD
  • PLC delta2 is markedly expressed in type II intestinal metaplasia and in the adenocarcinoma
  • When PLC delta2 is expressed in type I intestinal metaplasia, the metaplasia is generally considered benignant, yet evolves toward neoplastic transformation
  • Thus, PLC delta2 expression may be a possible marker of gastric malignant transformation.

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Thermo Scientific

PIMA528034

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Antigen:
Phospho-PLCg2 (Tyr759)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P16885, Q8CIH5

Gene Symbols:
Plcg2

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr759 of human phospho PLCgamma2.

Quantity:
200μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry, Western Blot

Clone:
PLCG2Y759-G3

Conjugate:
Unconjugated

Gene:
Plcg2

Gene Alias:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
234779, 5336

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA528038

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Antigen:
Phospho-MEK1/MEK2 (Ser221)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P31938, P36507, Q02750, Q63932

Gene Symbols:
MAP2K1, MAP2K2

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser221 of human phospho MEK1/2.

Quantity:
200μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry, Western Blot

Clone:
MEK12S221-D3

Conjugate:
Unconjugated

Gene:
MAP2K2

Gene Alias:
AA589381; CFC3; CFC4; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 2; EC 2.7.12.2; ERK activator kinase 1; ERK activator kinase 2; hypothetical protein; hypothetical protein LOC406728; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP kinase/Erk kinase 1; Map2k1; Map2k2; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK1; MAPKK2; MEK 1; MEK 2; Mek1; MEK-1; Mek2; MEK-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; mitogen-activated protein kinase kinase type 2; MK2; MKK1; MKK2; MP2K1; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen activated, kinase 2, p45; protein kinase, mitogen-activated, ki

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
26395, 26396, 5604, 5605

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA528039

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Antigen:
Phospho-MEK1 (Ser298)

Classification:
Recombinant Monoclonal

Concentration:
__

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q01986, Q02750

Gene Symbols:
Map2k1

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser298 of human phospho MEK1

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
MEK1S298-H8

Conjugate:
APC

Gene:
Map2k1

Gene Alias:
CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
170851, 5604

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA528040

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Antigen:
Phospho-MEK1 (Ser298)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q01986, Q02750

Gene Symbols:
Map2k1

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser298 of human phospho MEK1.

Quantity:
200μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry, Western Blot

Clone:
MEK1S298-H8

Conjugate:
Unconjugated

Gene:
Map2k1

Gene Alias:
CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
170851, 5604

Content And Storage:
-20°C

Form:
Liquid