PIMA528084
Complement Factor Bb Neoantigen Monoclonal Antibody (032B-22.1.X), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA528084-Each-of-1 | In Stock | ₹ 77,517.36 |
PIMA528084 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 77,517.36
GST (18%): ₹ 13,953.125
Total Price: ₹ 91,470.485
Antigen
Complement Factor Bb Neoantigen
Classification
Monoclonal
Concentration
1.125 mg/mL
Formulation
BBS with <0.1% sodium azide
Gene Accession No.
P00751
Gene Symbols
CFB
Immunogen
Purified Human factor B
Quantity
100μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
ELISA
Clone
032B-22.1.X
Conjugate
Unconjugated
Gene
CFB
Gene Alias
AHUS4; ARMD14; BF; B-factor, properdin; BFD; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFB; CFBD; Complement factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; FB; FBI12; GBG; glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; H2-Bf; PBF2; Properdin factor B
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
629
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody recognizes a neoantigen of the Bb fragment of human complement factor B
- Factor B is present in blood serum
- C3b associates with complement factor B, inducing conformational change
- This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit) leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase
- Subunit Bb is involved in the proliferation of preactivated B lymphocytes
- Conversely, Ba inhibits lymphocyte proliferation
- CFB is involved in hemolytic uremic syndrome atypical 4 (AHUS4), an atypical form of hemolytic uremic syndrome
- It is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea
- In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease
- Disease susceptibility is associated with variations affecting the gene represented in this entry
- Susceptibility to the development of atypical hemolytic uremic syndrome can be conferred by mutations in various components of or regulatory factors in the complement cascade system
- Other genes may play a role in modifying the phenotype.
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Antigen: Complement Factor Bb Neoantigen
Classification: Monoclonal
Concentration: 1.125 mg/mL
Formulation: BBS with <0.1% sodium azide
Gene Accession No.: P00751
Gene Symbols: CFB
Immunogen: Purified Human factor B
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: ELISA
Clone: 032B-22.1.X
Conjugate: Unconjugated
Gene: CFB
Gene Alias: AHUS4; ARMD14; BF; B-factor, properdin; BFD; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFB; CFBD; Complement factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; FB; FBI12; GBG; glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; H2-Bf; PBF2; Properdin factor B
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 629
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Complement Factor Bb Neoantigen
Classification:
Monoclonal
Concentration:
1.125 mg/mL
Formulation:
BBS with <0.1% sodium azide
Gene Accession No.:
P00751
Gene Symbols:
CFB
Immunogen:
Purified Human factor B
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
ELISA
Clone:
032B-22.1.X
Conjugate:
Unconjugated
Gene:
CFB
Gene Alias:
AHUS4; ARMD14; BF; B-factor, properdin; BFD; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFB; CFBD; Complement factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; FB; FBI12; GBG; glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; H2-Bf; PBF2; Properdin factor B
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
629
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Complement Factor Bb
Classification: Monoclonal
Concentration: 1.05 mg/mL
Formulation: BBS with 0.1% sodium azide
Gene Accession No.: P00751
Gene Symbols: CFB
Immunogen: Human factor B
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
Clone: 10-09
Conjugate: Unconjugated
Gene: CFB
Gene Alias: AHUS4; ARMD14; BF; B-factor, properdin; BFD; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFB; CFBD; Complement factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; FB; FBI12; GBG; Glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; H2-Bf; PBF2; properdin factor B
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 629
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Complement Factor Bb
Classification:
Monoclonal
Concentration:
1.05 mg/mL
Formulation:
BBS with 0.1% sodium azide
Gene Accession No.:
P00751
Gene Symbols:
CFB
Immunogen:
Human factor B
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
Clone:
10-09
Conjugate:
Unconjugated
Gene:
CFB
Gene Alias:
AHUS4; ARMD14; BF; B-factor, properdin; BFD; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFB; CFBD; Complement factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; FB; FBI12; GBG; Glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; H2-Bf; PBF2; properdin factor B
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
629
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Complement C3c
Classification: Monoclonal
Concentration: 1.2 mg/mL
Formulation: BBS with 0.1% sodium azide
Gene Accession No.: P01024
Gene Symbols: C3
Immunogen: Human C3 from normal serum, highly purified by chromatography
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
Clone: 10-02A
Conjugate: Unconjugated
Gene: C3
Gene Alias: Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; C3d; complement C3; Complement C3 alpha chain; Complement C3 beta chain; complement C3 protein (GPC3) precursor; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component 3d; complement component C3; complement component C3 alpha-chain; complement component C3a; complement component C3b; complement component C3d; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; LOC101108131; LOW QUALITY PROTEIN: complement C3; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3; Unknown (protein for MGC:134562)
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 718
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Complement C3c
Classification:
Monoclonal
Concentration:
1.2 mg/mL
Formulation:
BBS with 0.1% sodium azide
Gene Accession No.:
P01024
Gene Symbols:
C3
Immunogen:
Human C3 from normal serum, highly purified by chromatography
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
Clone:
10-02A
Conjugate:
Unconjugated
Gene:
C3
Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; C3d; complement C3; Complement C3 alpha chain; Complement C3 beta chain; complement C3 protein (GPC3) precursor; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component 3d; complement component C3; complement component C3 alpha-chain; complement component C3a; complement component C3b; complement component C3d; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; LOC101108131; LOW QUALITY PROTEIN: complement C3; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3; Unknown (protein for MGC:134562)
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
718
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: C5AR1
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 1% BSA and 0.09% sodium azide
Gene Accession No.: P21730
Gene Symbols: C5AR1
Immunogen: C5aR - peptide Met1- Asn31
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry
Clone: P12/1
Conjugate: FITC
Gene: C5AR1
Gene Alias: anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 728
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form: Liquid
Antigen:
C5AR1
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 1% BSA and 0.09% sodium azide
Gene Accession No.:
P21730
Gene Symbols:
C5AR1
Immunogen:
C5aR - peptide Met1- Asn31
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry
Clone:
P12/1
Conjugate:
FITC
Gene:
C5AR1
Gene Alias:
anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
728
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form:
Liquid