PIMA528538
Phospho-CD247 (CD3 zeta) (Tyr142) Monoclonal Antibody (EM-54), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA528538-Each-of-1 | In Stock | ₹ 17,625.36 |
PIMA528538 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,625.36
GST (18%): ₹ 3,172.565
Total Price: ₹ 20,797.925
Antigen
Phospho-CD247 (CD3 zeta) (Tyr142)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P20963, P24161
Gene Symbols
CD247
Immunogen
CP1 (pTyr142) - KLH
Quantity
100μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Western Blot
Clone
EM-54
Conjugate
Unconjugated
Gene
CD247
Gene Alias
4930549J05Rik; A430104F18Rik; antigen CD3Z, zeta polypeptide; AW552088; Cd247; CD247 antigen; CD247 antigen, zeta subunit; Cd247 molecule; Cd3; CD3 antigen, zeta polypeptide; CD3 zeta; CD3 zeta chain; CD3e antigen; CD3-epsilon; Cd3-eta; CD3H; CD3Q; Cd3z; CD3Z antigen, zeta polypeptide (TiT3 complex); Cd3zeta; Cd3-zeta; CD3zeta chain; CD3-zeta/eta; FLJ18683; IMD25; T3E; T3z; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor CD3 subunit zeta; T-cell receptor CD3, subunit zeta; T-cell receptor T3 eta chain; T-cell receptor T3 zeta chain; T-cell receptor zeta chain; T-cell surface glycoprotein CD3 zeta chain; TCR zeta chain; TCRE; Tcrk; TCRZ; TCRzeta
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
12503, 919
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- The mouse monoclonal antibody EM-54 recognizes phosphorylated tyrosine 142 of CD3 zeta chain (CD247), which is a component of TCR/CD3 complex expressed on T cells
- CD3z complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex
- T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta
- These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11
- The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules, and this association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits
- CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation
- The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum
- It is never expressed on B or NK cells
- Decreased percentages of T lymphocytes may be observed in some autoimmune diseases
- Diseases associated with CD3z include Immunodeficiency 25 and T-B+ Severe Combined Immunodeficiency Due To Cd3delta/Cd3epsilon/Cd3zeta.
Compare Similar Items
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Antigen: Phospho-CD247 (CD3 zeta) (Tyr142)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P20963, P24161
Gene Symbols: CD247
Immunogen: CP1 (pTyr142) - KLH
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Western Blot
Clone: EM-54
Conjugate: Unconjugated
Gene: CD247
Gene Alias: 4930549J05Rik; A430104F18Rik; antigen CD3Z, zeta polypeptide; AW552088; Cd247; CD247 antigen; CD247 antigen, zeta subunit; Cd247 molecule; Cd3; CD3 antigen, zeta polypeptide; CD3 zeta; CD3 zeta chain; CD3e antigen; CD3-epsilon; Cd3-eta; CD3H; CD3Q; Cd3z; CD3Z antigen, zeta polypeptide (TiT3 complex); Cd3zeta; Cd3-zeta; CD3zeta chain; CD3-zeta/eta; FLJ18683; IMD25; T3E; T3z; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor CD3 subunit zeta; T-cell receptor CD3, subunit zeta; T-cell receptor T3 eta chain; T-cell receptor T3 zeta chain; T-cell receptor zeta chain; T-cell surface glycoprotein CD3 zeta chain; TCR zeta chain; TCRE; Tcrk; TCRZ; TCRzeta
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12503, 919
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
Phospho-CD247 (CD3 zeta) (Tyr142)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P20963, P24161
Gene Symbols:
CD247
Immunogen:
CP1 (pTyr142) - KLH
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Western Blot
Clone:
EM-54
Conjugate:
Unconjugated
Gene:
CD247
Gene Alias:
4930549J05Rik; A430104F18Rik; antigen CD3Z, zeta polypeptide; AW552088; Cd247; CD247 antigen; CD247 antigen, zeta subunit; Cd247 molecule; Cd3; CD3 antigen, zeta polypeptide; CD3 zeta; CD3 zeta chain; CD3e antigen; CD3-epsilon; Cd3-eta; CD3H; CD3Q; Cd3z; CD3Z antigen, zeta polypeptide (TiT3 complex); Cd3zeta; Cd3-zeta; CD3zeta chain; CD3-zeta/eta; FLJ18683; IMD25; T3E; T3z; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor CD3 subunit zeta; T-cell receptor CD3, subunit zeta; T-cell receptor T3 eta chain; T-cell receptor T3 zeta chain; T-cell receptor zeta chain; T-cell surface glycoprotein CD3 zeta chain; TCR zeta chain; TCRE; Tcrk; TCRZ; TCRzeta
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12503, 919
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: Phospho-CD247 (CD3 zeta) (Tyr111, Tyr123)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 15mM sodium azide; pH 7.4
Gene Accession No.: P20963, P24161
Gene Symbols: CD247
Immunogen: BP1 (pTyr111/123) - KLH
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Western Blot
Clone: EM-55
Conjugate: Unconjugated
Gene: CD247
Gene Alias: 4930549J05Rik; A430104F18Rik; antigen CD3Z, zeta polypeptide; AW552088; Cd247; CD247 antigen; CD247 antigen, zeta subunit; Cd247 molecule; Cd3; CD3 antigen, zeta polypeptide; CD3 zeta; CD3 zeta chain; CD3e antigen; CD3-epsilon; Cd3-eta; CD3H; CD3Q; Cd3z; CD3Z antigen, zeta polypeptide (TiT3 complex); Cd3zeta; Cd3-zeta; CD3zeta chain; CD3-zeta/eta; FLJ18683; IMD25; T3E; T3z; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor CD3 subunit zeta; T-cell receptor CD3, subunit zeta; T-cell receptor T3 eta chain; T-cell receptor T3 zeta chain; T-cell receptor zeta chain; T-cell surface glycoprotein CD3 zeta chain; TCR zeta chain; TCRE; Tcrk; TCRZ; TCRzeta
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12503, 919
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
Phospho-CD247 (CD3 zeta) (Tyr111, Tyr123)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.:
P20963, P24161
Gene Symbols:
CD247
Immunogen:
BP1 (pTyr111/123) - KLH
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Western Blot
Clone:
EM-55
Conjugate:
Unconjugated
Gene:
CD247
Gene Alias:
4930549J05Rik; A430104F18Rik; antigen CD3Z, zeta polypeptide; AW552088; Cd247; CD247 antigen; CD247 antigen, zeta subunit; Cd247 molecule; Cd3; CD3 antigen, zeta polypeptide; CD3 zeta; CD3 zeta chain; CD3e antigen; CD3-epsilon; Cd3-eta; CD3H; CD3Q; Cd3z; CD3Z antigen, zeta polypeptide (TiT3 complex); Cd3zeta; Cd3-zeta; CD3zeta chain; CD3-zeta/eta; FLJ18683; IMD25; T3E; T3z; T-cell antigen receptor complex, zeta subunit of CD3; T-cell receptor CD3 subunit zeta; T-cell receptor CD3, subunit zeta; T-cell receptor T3 eta chain; T-cell receptor T3 zeta chain; T-cell receptor zeta chain; T-cell surface glycoprotein CD3 zeta chain; TCR zeta chain; TCRE; Tcrk; TCRZ; TCRzeta
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12503, 919
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: CD79a
Classification: Monoclonal
Concentration: __
Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.: P11911, P11912, P40293
Gene Symbols: CD79A
Immunogen: Synthetic peptide corresponding to amino acids 202-216 human CD79a
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Bovine, Chicken, Equine, Guinea Pig, Human, Marsupial, Mouse, Porcine, Rabbit, Rat, Rodent
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry
Clone: HM57
Conjugate: FITC
Gene: CD79A
Gene Alias: B-cell antigen receptor; B-cell antigen receptor complex-associated protein alpha chain; B-cell antigen receptor complex-associated protein alpha chain-like; CD79; CD79a; CD79A antigen (immunoglobulin-associated alpha); CD79a molecule; CD79a molecule, immunoglobulin-associated alpha; CD79A protein; CD79-alpha protein; EGK_10665; Ig alpha; IGA; Igalpha; ig-alpha; immunoglobulin-associated alpha; LOC100913063; Ly54; Ly-54; MB1; MB-1; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; surface IgM-associated protein
Host Species: Mouse
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100052219, 100190992, 100724815, 100913063, 12518, 281674, 973
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
CD79a
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.:
P11911, P11912, P40293
Gene Symbols:
CD79A
Immunogen:
Synthetic peptide corresponding to amino acids 202-216 human CD79a
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Bovine, Chicken, Equine, Guinea Pig, Human, Marsupial, Mouse, Porcine, Rabbit, Rat, Rodent
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
HM57
Conjugate:
FITC
Gene:
CD79A
Gene Alias:
B-cell antigen receptor; B-cell antigen receptor complex-associated protein alpha chain; B-cell antigen receptor complex-associated protein alpha chain-like; CD79; CD79a; CD79A antigen (immunoglobulin-associated alpha); CD79a molecule; CD79a molecule, immunoglobulin-associated alpha; CD79A protein; CD79-alpha protein; EGK_10665; Ig alpha; IGA; Igalpha; ig-alpha; immunoglobulin-associated alpha; LOC100913063; Ly54; Ly-54; MB1; MB-1; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; surface IgM-associated protein
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100052219, 100190992, 100724815, 100913063, 12518, 281674, 973
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: Drebrin
Classification: Monoclonal
Concentration: __
Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.: Q16643
Gene Symbols: DBN1
Immunogen: human drebrin (aa 1-326, N terminal)
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry
Clone: DBN-N-03
Conjugate: PE
Gene: DBN1
Gene Alias: D0S117E; Dbn1; developmentally regulated brain protein; developmentally-regulated brain protein; DKFZp434D064; Drba; Drebrin; drebrin 1; drebrin A; drebrin E; drebrin E2; drebrin-1; Unknown (protein for MGC:138067)
Host Species: Mouse
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1627
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
Drebrin
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.:
Q16643
Gene Symbols:
DBN1
Immunogen:
human drebrin (aa 1-326, N terminal)
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry
Clone:
DBN-N-03
Conjugate:
PE
Gene:
DBN1
Gene Alias:
D0S117E; Dbn1; developmentally regulated brain protein; developmentally-regulated brain protein; DKFZp434D064; Drba; Drebrin; drebrin 1; drebrin A; drebrin E; drebrin E2; drebrin-1; Unknown (protein for MGC:138067)
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1627
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid