PIMA528631
RLTPR Monoclonal Antibody (EM-53), PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA528631-Each-of-1 | In Stock | ₹ 44,790.66 |
PIMA528631 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,790.66
GST (18%): ₹ 8,062.319
Total Price: ₹ 52,852.979
Antigen
RLTPR
Classification
Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.
Q3V3V9, Q6F5E8
Gene Symbols
CARMIL2
Immunogen
Murine Rltpr (amino acids 1147-1397)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
EM-53
Conjugate
PE
Gene
CARMIL2
Gene Alias
Capping protein regulator and myosin 1 linker 2; capping protein, Arp2/3 and myosin-I linker protein 2; CARMIL2; CARMIL2b; CG1399-PB; D130029J02Rik; F-actin-uncapping protein RLTPR; Gm585; leucine rich repeat containing 16C; leucine-rich repeat-containing protein 16C; LRRC16C; RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing; RGD, leucine-rich repeat, tropomodulin and proline-rich containing protein; RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein; RLTPR
Host Species
Mouse
Purification Method
Size-exclusion chromatography
Regulatory Status
RUO
Gene ID (Entrez)
146206, 234695
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Related Products
Description
- The mouse monoclonal antibody EM-53 recognizes RLTPR / CARMIL2, a protein playing a role in actin filament elongation
- RLTPR/CARMIL2 (RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing; capping protein regulator and myosin 1 linker 2), also known as LRRC16C, is a cytosolic protein, which with high affinity binds CAPZA2 (capping protein muscle actin Z-line alpha 2) and decreases CAPZA2 affinity for actin barbed ends
- RLTPR/CARMIL2 increases the rate of actin filament elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments
- Its interaction with CAPZA2 is essential for lamellipodial protrusion and cell translocation
- RLTPR/CARMIL2 is crucial for T cell costimulation via CD28 and this property seems to be independent on its actin-uncapping function
- The lack of functional RLTPR/CARMIL2 molecules impeded the differentiation toward Th1 and Th17 fates of both human and murine CD4+ T cells and leads to combined immunodeficiency
- Expression of RLTPR/CARMIL2 was also detected in human and murine B cells, but it seems not to be involved in BCR-mediated signaling.
Compare Similar Items
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Antigen: RLTPR
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.: Q3V3V9, Q6F5E8
Gene Symbols: CARMIL2
Immunogen: Murine Rltpr (amino acids 1147-1397)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: EM-53
Conjugate: PE
Gene: CARMIL2
Gene Alias: Capping protein regulator and myosin 1 linker 2; capping protein, Arp2/3 and myosin-I linker protein 2; CARMIL2; CARMIL2b; CG1399-PB; D130029J02Rik; F-actin-uncapping protein RLTPR; Gm585; leucine rich repeat containing 16C; leucine-rich repeat-containing protein 16C; LRRC16C; RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing; RGD, leucine-rich repeat, tropomodulin and proline-rich containing protein; RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein; RLTPR
Host Species: Mouse
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): 146206, 234695
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
RLTPR
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.:
Q3V3V9, Q6F5E8
Gene Symbols:
CARMIL2
Immunogen:
Murine Rltpr (amino acids 1147-1397)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
EM-53
Conjugate:
PE
Gene:
CARMIL2
Gene Alias:
Capping protein regulator and myosin 1 linker 2; capping protein, Arp2/3 and myosin-I linker protein 2; CARMIL2; CARMIL2b; CG1399-PB; D130029J02Rik; F-actin-uncapping protein RLTPR; Gm585; leucine rich repeat containing 16C; leucine-rich repeat-containing protein 16C; LRRC16C; RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing; RGD, leucine-rich repeat, tropomodulin and proline-rich containing protein; RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein; RLTPR
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
146206, 234695
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: STRO-1
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: TBS with 0.2% BSA and 15mM sodium azide; pH 8
Gene Accession No.: __
Gene Symbols: __
Immunogen: Human CD34 positive bone marrow cells
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rabbit, Rat
Product Type: Antibody
Isotype: IgM λ
Applications: Flow Cytometry
Clone: STRO-1
Conjugate: APC
Gene: __
Gene Alias: STRO1
Host Species: Mouse
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
STRO-1
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
TBS with 0.2% BSA and 15mM sodium azide; pH 8
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Human CD34 positive bone marrow cells
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgM λ
Applications:
Flow Cytometry
Clone:
STRO-1
Conjugate:
APC
Gene:
__
Gene Alias:
STRO1
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: STRO-1
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: TBS with 0.2% BSA and 15mM sodium azide; pH 8
Gene Accession No.: __
Gene Symbols: __
Immunogen: Human CD34 positive bone marrow cells
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rabbit, Rat
Product Type: Antibody
Isotype: IgM λ
Applications: Flow Cytometry
Clone: STRO-1
Conjugate: PE
Gene: __
Gene Alias: STRO1
Host Species: Mouse
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
STRO-1
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
TBS with 0.2% BSA and 15mM sodium azide; pH 8
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Human CD34 positive bone marrow cells
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgM λ
Applications:
Flow Cytometry
Clone:
STRO-1
Conjugate:
PE
Gene:
__
Gene Alias:
STRO1
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: Bcl-xL
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with <0.1% sodium azide
Gene Accession No.: P53563, Q07817, Q64373
Gene Symbols: BCL2L1
Immunogen: Recombinant human Bcl-xS
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat, Rhesus Monkey
Product Type: Antibody
Isotype: IgG3 κ
Applications: Flow Cytometry
Clone: 7B2.5
Conjugate: FITC
Gene: BCL2L1
Gene Alias: anti-apoptosis regulatory protein; apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; B-cell leukemia/lymphoma x; Bcl(X)L; BCL2 like 1; Bcl2l; BCL2L1; bcl2-L-1; BCL2-like 1; Bcl-2-like protein 1; BCLX; bcl-x; BCLXL; Bcl-XL; BCL-XL/S; BCLXS; bcl-xS; Blc2l; DKFZp781P2092; EGK_02534; OTTHUMP00000030550; OTTHUMP00000030552; OTTHUMP00000030555; OTTHUMP00000030556; OTTHUMP00000030557; PPP1R52; protein phosphatase 1, regulatory subunit 52; RP5-857M17.3
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 12048, 24888, 598, 713035
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
Bcl-xL
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with <0.1% sodium azide
Gene Accession No.:
P53563, Q07817, Q64373
Gene Symbols:
BCL2L1
Immunogen:
Recombinant human Bcl-xS
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG3 κ
Applications:
Flow Cytometry
Clone:
7B2.5
Conjugate:
FITC
Gene:
BCL2L1
Gene Alias:
anti-apoptosis regulatory protein; apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; B-cell leukemia/lymphoma x; Bcl(X)L; BCL2 like 1; Bcl2l; BCL2L1; bcl2-L-1; BCL2-like 1; Bcl-2-like protein 1; BCLX; bcl-x; BCLXL; Bcl-XL; BCL-XL/S; BCLXS; bcl-xS; Blc2l; DKFZp781P2092; EGK_02534; OTTHUMP00000030550; OTTHUMP00000030552; OTTHUMP00000030555; OTTHUMP00000030556; OTTHUMP00000030557; PPP1R52; protein phosphatase 1, regulatory subunit 52; RP5-857M17.3
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
12048, 24888, 598, 713035
Content And Storage:
4° C, store in dark
Form:
Liquid