PIMA528652
CD22 Monoclonal Antibody (2D6), Biotin, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA528652-Each-of-1 | In Stock | ₹ 41,710.50 |
PIMA528652 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,710.50
GST (18%): ₹ 7,507.89
Total Price: ₹ 49,218.39
Antigen
CD22
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with <0.1% sodium azide
Gene Accession No.
P35329
Gene Symbols
CD22
Immunogen
Splenic lymphocyte plasma membranes from CBA x C57 F1 mice
Quantity
1 mL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
2D6
Conjugate
Biotin
Gene
CD22
Gene Alias
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Host Species
Rat
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
12483
Content And Storage
4° C
Form
Liquid
Related Products
Description
- CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa
- CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes
- CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen
- Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias
- CD22 is also strongly expressed in hairy cell leukemia
- CD22 preferentially binds to alpha2,6-linked sialic acid
- The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface
- Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling
- CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules
- CD22 is also strongly expressed in hairy cell leukemia
- CD22 is also positive in diffuse large B-cell lymphoma and nodular lymphocyte predominance Hodgkin’s lymphoma, but negative in classical Hodgkin’s lymphoma.
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Antigen: CD22
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with <0.1% sodium azide
Gene Accession No.: P35329
Gene Symbols: CD22
Immunogen: Splenic lymphocyte plasma membranes from CBA x C57 F1 mice
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 2D6
Conjugate: Biotin
Gene: CD22
Gene Alias: A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Host Species: Rat
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 12483
Content And Storage: 4° C
Form: Liquid
Antigen:
CD22
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with <0.1% sodium azide
Gene Accession No.:
P35329
Gene Symbols:
CD22
Immunogen:
Splenic lymphocyte plasma membranes from CBA x C57 F1 mice
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
2D6
Conjugate:
Biotin
Gene:
CD22
Gene Alias:
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Host Species:
Rat
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
12483
Content And Storage:
4° C
Form:
Liquid
Antigen: CD22
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: BBS with no preservative; pH 8.2
Gene Accession No.: P35329
Gene Symbols: CD22
Immunogen: Splenic lymphocyte plasma membranes from CBA x C57 F1 mice
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 2D6
Conjugate: Unconjugated
Gene: CD22
Gene Alias: A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Host Species: Rat
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 12483
Content And Storage: 4° C
Form: Liquid
Antigen:
CD22
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
BBS with no preservative; pH 8.2
Gene Accession No.:
P35329
Gene Symbols:
CD22
Immunogen:
Splenic lymphocyte plasma membranes from CBA x C57 F1 mice
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
2D6
Conjugate:
Unconjugated
Gene:
CD22
Gene Alias:
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14
Host Species:
Rat
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
12483
Content And Storage:
4° C
Form:
Liquid
Antigen: CD28
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with sucrose and <0.1% sodium azide
Gene Accession No.: P31041
Gene Symbols: Cd28
Immunogen: C57BL/6N mouse T cell lymphoma EL-4 cell line
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2
Applications: Flow Cytometry
Clone: 37.51
Conjugate: PE-Cyanine5
Gene: Cd28
Gene Alias: antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species: Syrian Hamster
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 12487
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
CD28
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with sucrose and <0.1% sodium azide
Gene Accession No.:
P31041
Gene Symbols:
Cd28
Immunogen:
C57BL/6N mouse T cell lymphoma EL-4 cell line
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2
Applications:
Flow Cytometry
Clone:
37.51
Conjugate:
PE-Cyanine5
Gene:
Cd28
Gene Alias:
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Host Species:
Syrian Hamster
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
12487
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Antigen: Lyb-2.1
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with sucrose and <0.1% sodium azide
Gene Accession No.: P21855
Gene Symbols: Cd72
Immunogen: DBA/2 mouse spleen cells
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: 10.1.D2
Conjugate: APC
Gene: Cd72
Gene Alias: B-cell differentiation antigen CD72; CD72; CD72 antigen; CD72c; Ly-19; Ly32; Ly-32; Lyb-2; Ly-m19; lymphocyte antigen 32
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 12517
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
Lyb-2.1
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with sucrose and <0.1% sodium azide
Gene Accession No.:
P21855
Gene Symbols:
Cd72
Immunogen:
DBA/2 mouse spleen cells
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
10.1.D2
Conjugate:
APC
Gene:
Cd72
Gene Alias:
B-cell differentiation antigen CD72; CD72; CD72 antigen; CD72c; Ly-19; Ly32; Ly-32; Lyb-2; Ly-m19; lymphocyte antigen 32
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
12517
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid