PIMA528681

CD45 Monoclonal Antibody (LT40), PE-Cyanine5, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA528681-Each-of-1 In Stock ₹ 39,571.50

PIMA528681 - Each of 1

₹ 39,571.50

In Stock

Quantity

1

Base Price: ₹ 39,571.50

GST (18%): ₹ 7,122.87

Total Price: ₹ 46,694.37

Antigen

CD45

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with sucrose and <0.1% sodium azide

Gene Accession No.

0

Gene Symbols

PTPRC

Immunogen

Chicken bursal lymphocytes

Quantity

1 mL

Primary or Secondary

Primary

Target Species

Chicken

Product Type

Antibody

Isotype

IgM κ

Applications

Flow Cytometry

Clone

LT40

Conjugate

PE-Cyanine5

Gene

PTPRC

Gene Alias

B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

386580

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
  • CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling
  • CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.

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Img

Thermo Scientific

PIMA528681

--


Antigen:
CD45

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with sucrose and <0.1% sodium azide

Gene Accession No.:
0

Gene Symbols:
PTPRC

Immunogen:
Chicken bursal lymphocytes

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Chicken

Product Type:
Antibody

Isotype:
IgM κ

Applications:
Flow Cytometry

Clone:
LT40

Conjugate:
PE-Cyanine5

Gene:
PTPRC

Gene Alias:
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
386580

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA528682

--


Antigen:
CD45

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
BBS with no preservative; pH 8.2

Gene Accession No.:
0

Gene Symbols:
PTPRC

Immunogen:
Chicken bursal lymphocytes

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Chicken

Product Type:
Antibody

Isotype:
IgM κ

Applications:
Flow Cytometry

Clone:
LT40

Conjugate:
Unconjugated

Gene:
PTPRC

Gene Alias:
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
386580

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA528683

--


Antigen:
CD4

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with sucrose and <0.1% sodium azide

Gene Accession No.:
0

Gene Symbols:
CD4

Immunogen:
Chicken thymocytes and Ig-negative blood leukocytes

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Avian, Chicken

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
CT-4

Conjugate:
APC

Gene:
CD4

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
101790140, 395362

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA528684

--


Antigen:
CD4

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
0

Gene Symbols:
CD4

Immunogen:
Chicken thymocytes and Ig-negative blood leukocytes

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Avian, Chicken

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
CT-4

Conjugate:
Biotin

Gene:
CD4

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
101790140, 395362

Content And Storage:
4° C

Form:
Liquid