PIMA529220
DIABLO Recombinant Rabbit Monoclonal Antibody (006), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA529220-Each-of-1 | In Stock | ₹ 39,785.40 |
PIMA529220 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,785.40
GST (18%): ₹ 7,161.372
Total Price: ₹ 46,946.772
Antigen
DIABLO
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7
Gene Accession No.
Q9NR28
Gene Symbols
DIABLO
Immunogen
Recombinant Human SMAC/Diablo protein (Ala56-Asp239)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone
006
Conjugate
Unconjugated
Gene
DIABLO
Gene Alias
0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; Smac; Smac protein; SMAC3
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
56616
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human SMAC/Diablo
- DIABLO (smac), a mitochondrial protein, activates various forms of apoptosis
- This activation may be due to the neutralization of one or more members of the IAP family of apoptosis inhibitory proteins
- Smac exits the mitochondria and enter the cytosol during certain apoptosis triggered events
- Mitochondrial-mediated apoptosis is important in animal development and tissue homeostasis, with alterations resulting in a range of malignant disorders
- Upon apoptotic stimuli, the mitochondrial proteins cytochrome c and Smac/DIABLO are released into the cytosol
- The release of these proteins, however, occurs via different mechanisms
- Smac/DIABLO has also been found to play a key role in regulating the sensitization of cancer cells to apoptosis (both immune and drug-induced).
Compare Similar Items
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Antigen: DIABLO
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7
Gene Accession No.: Q9NR28
Gene Symbols: DIABLO
Immunogen: Recombinant Human SMAC/Diablo protein (Ala56-Asp239)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone: 006
Conjugate: Unconjugated
Gene: DIABLO
Gene Alias: 0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; Smac; Smac protein; SMAC3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 56616
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
DIABLO
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7
Gene Accession No.:
Q9NR28
Gene Symbols:
DIABLO
Immunogen:
Recombinant Human SMAC/Diablo protein (Ala56-Asp239)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
006
Conjugate:
Unconjugated
Gene:
DIABLO
Gene Alias:
0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; Smac; Smac protein; SMAC3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
56616
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: DYDC2
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q96IM9
Gene Symbols: DYDC2
Immunogen: Recombinant Human DPY30 domain containing 2/DYDC2 Protein (Thr102-Pro176)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry
Clone: 101
Conjugate: Unconjugated
Gene: DYDC2
Gene Alias: bA36D19.6; DPY30 domain containing 2; DPY30 domain-containing protein 2; DYDC2; MGC16186; SPS1; SRML1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 84332
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
DYDC2
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q96IM9
Gene Symbols:
DYDC2
Immunogen:
Recombinant Human DPY30 domain containing 2/DYDC2 Protein (Thr102-Pro176)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry
Clone:
101
Conjugate:
Unconjugated
Gene:
DYDC2
Gene Alias:
bA36D19.6; DPY30 domain containing 2; DPY30 domain-containing protein 2; DYDC2; MGC16186; SPS1; SRML1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
84332
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: RCAS1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O00559
Gene Symbols: EBAG9
Immunogen: Recombinant Human RCAS1/EBAG9 Protein (Arg28-Ser213)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Western Blot
Clone: 019
Conjugate: Unconjugated
Gene: EBAG9
Gene Alias: AI835379; BAG9; cancer associated surface antigen; cancer associated surface antigen RCAS1; cancer-associated surface antigen RCAS1; EB9; EBAG9; estrogen receptor binding fragment associated gene 9; estrogen receptor binding site associated, antigen, 9; estrogen receptor-binding fragment-associated gene 9; estrogen receptor-binding fragment-associated gene 9 protein; HGNC:3123; PDAF; Rcas1; receptor binding cancer antigen expressed on SiSo cells; Receptor-binding cancer antigen expressed on SiSo cells
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 9166
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RCAS1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O00559
Gene Symbols:
EBAG9
Immunogen:
Recombinant Human RCAS1/EBAG9 Protein (Arg28-Ser213)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Western Blot
Clone:
019
Conjugate:
Unconjugated
Gene:
EBAG9
Gene Alias:
AI835379; BAG9; cancer associated surface antigen; cancer associated surface antigen RCAS1; cancer-associated surface antigen RCAS1; EB9; EBAG9; estrogen receptor binding fragment associated gene 9; estrogen receptor binding site associated, antigen, 9; estrogen receptor-binding fragment-associated gene 9; estrogen receptor-binding fragment-associated gene 9 protein; HGNC:3123; PDAF; Rcas1; receptor binding cancer antigen expressed on SiSo cells; Receptor-binding cancer antigen expressed on SiSo cells
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
9166
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: ECH1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q13011
Gene Symbols: ECH1
Immunogen: Recombinant Human ECH1 Protein (Thr34-Leu328)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Western Blot
Clone: 002
Conjugate: Unconjugated
Gene: ECH1
Gene Alias: AA617331; delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; delta3,5-delta2,4-dienoyl-CoA isomerase; delta3,5-delta2,4-dienoyl-coenzyme A isomerase; dienoyl-CoA isomerase; ECH1; enoyl CoA hydratase 1, peroxisomal; enoyl coenzyme A hydratase 1, peroxisomal; enoyl hydratase-like protein peroxisomal; enoyl hydratase-like protein, peroxisomal; enoyl-CoA hydratase 1; enoyl-CoA hydratase 1, peroxisomal; HPXEL; Peroxisomal enoyl hydratase-like protein; peroxisomal enoyl-CoA hydratase 1; peroxisomal/mitochondrial dienoyl-CoA isomerase; Pxel
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1891
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
ECH1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q13011
Gene Symbols:
ECH1
Immunogen:
Recombinant Human ECH1 Protein (Thr34-Leu328)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Western Blot
Clone:
002
Conjugate:
Unconjugated
Gene:
ECH1
Gene Alias:
AA617331; delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; delta3,5-delta2,4-dienoyl-CoA isomerase; delta3,5-delta2,4-dienoyl-coenzyme A isomerase; dienoyl-CoA isomerase; ECH1; enoyl CoA hydratase 1, peroxisomal; enoyl coenzyme A hydratase 1, peroxisomal; enoyl hydratase-like protein peroxisomal; enoyl hydratase-like protein, peroxisomal; enoyl-CoA hydratase 1; enoyl-CoA hydratase 1, peroxisomal; HPXEL; Peroxisomal enoyl hydratase-like protein; peroxisomal enoyl-CoA hydratase 1; peroxisomal/mitochondrial dienoyl-CoA isomerase; Pxel
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1891
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid