PIMA529385

LAMP1 Recombinant Rabbit Monoclonal Antibody (107), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA529385-Each-of-1 In Stock ₹ 49,838.70

PIMA529385 - Each of 1

₹ 49,838.70

In Stock

Quantity

1

Base Price: ₹ 49,838.70

GST (18%): ₹ 8,970.966

Total Price: ₹ 58,809.666

Antigen

LAMP1

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P11279, P14562

Gene Symbols

LAMP1

Immunogen

Recombinant Human LAMP1 protein (Met1-Met382)

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

107

Conjugate

Unconjugated

Gene

LAMP1

Gene Alias

120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; LAMP-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

25328, 3916

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • This antibody has specificity for Human LAMP1/CD107a
  • LAMP1 (CD107a, lysosome-associated membrane protein-1) together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane
  • LAMP1 is a heavily glycosylated membrane protein which contains a putative signal peptide, 18 sites for N-linked glycosylation, a single membrane-spanning segment and a short (11 amino acid) cytosolic tail
  • The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes
  • LAMP1 is a type 1 integral membrane protein that is transported from trans-Golgi network to endosomes and then lysosomes
  • Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboyxl-terminal tyrosine based motif (YXXI)
  • Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1, and this mutant protein then cycles between the plasma membrane and the endosome
  • Cell surface LAMP1 (and LAMP2) have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore, they are possibly involved in the adhesion of PBMC to the site of inflammation
  • Increased LAMP1 immunoreactivity is observed in neurons and glial cells surrounding senile plaques in Alzheimer’s Disease (AD) cases, and is localized in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution
  • LAMP1 is a good marker of mast cell activation.

Compare Similar Items

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Img

Thermo Scientific

PIMA529385

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Antigen:
LAMP1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P11279, P14562

Gene Symbols:
LAMP1

Immunogen:
Recombinant Human LAMP1 protein (Met1-Met382)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
107

Conjugate:
Unconjugated

Gene:
LAMP1

Gene Alias:
120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; LAMP-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
25328, 3916

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA529386

--


Antigen:
LAMP3

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9UQV4

Gene Symbols:
LAMP3

Immunogen:
Recombinant Human CD208/DC-LAMP/LAMP3 protein (Lys28-Thr381)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry

Clone:
007

Conjugate:
Unconjugated

Gene:
LAMP3

Gene Alias:
1200002D17Rik; CD208; DC LAMP; DCLAMP; DC-LAMP; DC-lysosome-associated membrane glycoprotein; dendritic cells-lysosome associated membrane glycoprotein; LAMP; Lamp3; LAMP-3; lysosomal associated membrane protein 3; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; Protein TSC403; TSC403

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
27074

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA529388

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Antigen:
NGAL

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P80188

Gene Symbols:
LCN2

Immunogen:
Recombinant Human LCN2/NGAL protein (Met1-Gly198)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Western Blot

Clone:
128

Conjugate:
Unconjugated

Gene:
LCN2

Gene Alias:
24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; AW212229; HGNC:6526; HNL; LCN2; lipocalin 2; lipocalin 2 (oncogene 24p3); Lipocalin 24p3; Lipocalin2; Lipocalin-2; migration-stimulating factor inhibitor; MSFI; neutrophil gelatinase-associated lipocalin; NGAL; oncogene 24p3; OTTHUMP00000022240; p25; RP23-161B9.11; secreted inducible protein 24; Siderocalin; Siderocalin LCN2; Sip24; SV-40-induced 24P3 protein; uterocalin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3934

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA529389

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Antigen:
Galectin 1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P09382

Gene Symbols:
LGALS1

Immunogen:
Recombinant Human Galectin-1/LGALS1 protein (Met1-Asp135)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
001

Conjugate:
Unconjugated

Gene:
LGALS1

Gene Alias:
14 kDa laminin-binding protein; 14 kDa lectin; AA410090; beta-galactoside binding protein; beta-galactoside-binding lectin; beta-galactoside-binding lectin L-14-I; beta-galactoside-binding protein 14kDa; DKFZp686E23103; GAL1; GAL-1; Galaptin; Galbp; galectin 1; galectin 1; LGALS1; Galectin1; galectin-1; galectin-1-like protein; GBP; HBL; H-Galectin-1; HLBP14; HPL; L14; L-14.5; Lactose-binding lectin 1; Lect14; Lectin galactoside-binding soluble 1; lectin, galactose binding, soluble 1; lectin, galactoside binding soluble 1; lectin, galactoside-binding, soluble, 1; lectin, galactoside-binding, soluble, 1 (galectin 1); Lgals1; LGAS1; OPG-1; pm12; Putative MAPK-activating protein PM12; RL 14.5; similar to galactose-binding lectin; S-Lac lectin 1; unnamed protein product

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3956

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid