PIMA529441
IkB alpha Recombinant Rabbit Monoclonal Antibody (116), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA529441-Each-of-1 | In Stock | ₹ 39,785.40 |
PIMA529441 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,785.40
GST (18%): ₹ 7,161.372
Total Price: ₹ 46,946.772
Antigen
IkB alpha
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P25963, Q9Z1E3
Gene Symbols
NFKBIA
Immunogen
Recombinant Human IkB alpha/NFKBIA Protein (Phe2-Leu317)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
116
Conjugate
Unconjugated
Gene
NFKBIA
Gene Alias
AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18035, 4792
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human IkB alpha/NFKBIA
- IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity
- The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol
- The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus
- A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha
- These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses
- In humans, the gene is located on the q arm of chromosome 14
- Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB
- IkB kinase alpha (IKK alpha), previously designated CHUK, interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation Serines 32 and 36
- IKK alpha appears to be critical for NFkB activation in response to proinflammatory cytokines
- Phosphorylation of IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1
- The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma, and each appear to make essential contributions to IkB phosphorylation.
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Antigen: IkB alpha
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P25963, Q9Z1E3
Gene Symbols: NFKBIA
Immunogen: Recombinant Human IkB alpha/NFKBIA Protein (Phe2-Leu317)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 116
Conjugate: Unconjugated
Gene: NFKBIA
Gene Alias: AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18035, 4792
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
IkB alpha
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P25963, Q9Z1E3
Gene Symbols:
NFKBIA
Immunogen:
Recombinant Human IkB alpha/NFKBIA Protein (Phe2-Leu317)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
116
Conjugate:
Unconjugated
Gene:
NFKBIA
Gene Alias:
AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18035, 4792
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Kininogen 1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 5% trehalose and no preservative
Gene Accession No.: P01042
Gene Symbols: KNG1
Immunogen: Recombinant Human KNG1/Kininogen 1 Protein (Gln19-Ser644)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: ELISA
Clone: 2C8D9E4
Conjugate: Unconjugated
Gene: KNG1
Gene Alias: alpha-1-MAP; Alpha-2-thiol proteinase inhibitor; BDK; BK; Bradykinin; fitzgerald factor; high molecular weight kininogen; H-kininigen; HMWK; Ile-Ser-Bradykinin; Kallidin I; Kallidin II; kininogen; kininogen 1; kininogen 1-like 1; kininogen-1; Kininogen-1 heavy chain; Kininogen-1 light chain; Kng; Kng1; Kng1l1; L-kininogen; low molecular weight (LMW) T-kininogen II; Low molecular weight growth-promoting factor; Lysyl-bradykinin; Major acute phase protein; major acute phase protein (alpha-1-MAP); Thiostatin; T-kinin; T-kininogen 2; T-kininogen 2 heavy chain; T-kininogen 2 light chain; T-kininogen II; T-kininogen II heavy chain; T-kininogen II light chain; williams-Fitzgerald-Flaujeac factor
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3827
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Kininogen 1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 5% trehalose and no preservative
Gene Accession No.:
P01042
Gene Symbols:
KNG1
Immunogen:
Recombinant Human KNG1/Kininogen 1 Protein (Gln19-Ser644)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
ELISA
Clone:
2C8D9E4
Conjugate:
Unconjugated
Gene:
KNG1
Gene Alias:
alpha-1-MAP; Alpha-2-thiol proteinase inhibitor; BDK; BK; Bradykinin; fitzgerald factor; high molecular weight kininogen; H-kininigen; HMWK; Ile-Ser-Bradykinin; Kallidin I; Kallidin II; kininogen; kininogen 1; kininogen 1-like 1; kininogen-1; Kininogen-1 heavy chain; Kininogen-1 light chain; Kng; Kng1; Kng1l1; L-kininogen; low molecular weight (LMW) T-kininogen II; Low molecular weight growth-promoting factor; Lysyl-bradykinin; Major acute phase protein; major acute phase protein (alpha-1-MAP); Thiostatin; T-kinin; T-kininogen 2; T-kininogen 2 heavy chain; T-kininogen 2 light chain; T-kininogen II; T-kininogen II heavy chain; T-kininogen II light chain; williams-Fitzgerald-Flaujeac factor
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3827
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Neuroligin 1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q8N2Q7
Gene Symbols: Nlgn1
Immunogen: Recombinant Human Neuroligin 1/NLGN1 protein (Met1-Ser677)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin)
Clone: 079
Conjugate: Unconjugated
Gene: Nlgn1
Gene Alias: 6330415N05Rik; BB179718; Kiaa1070; MGC45115; mKIAA1070; neuroligin 1; neuroligin I; Neuroligin-1; NL1; NLG 1; Nlg1; NLGN1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 22871
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Neuroligin 1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q8N2Q7
Gene Symbols:
Nlgn1
Immunogen:
Recombinant Human Neuroligin 1/NLGN1 protein (Met1-Ser677)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin)
Clone:
079
Conjugate:
Unconjugated
Gene:
Nlgn1
Gene Alias:
6330415N05Rik; BB179718; Kiaa1070; MGC45115; mKIAA1070; neuroligin 1; neuroligin I; Neuroligin-1; NL1; NLG 1; Nlg1; NLGN1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
22871
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: NME1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P15531
Gene Symbols: NME1
Immunogen: Recombinant Human NME1/NDKA protein (Ala2-Glu152)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry
Clone: 01
Conjugate: Unconjugated
Gene: NME1
Gene Alias: AL024257; AWD; expressed in non-metastatic cells 1; expressed in non-metastatic cells 1 protein; expressed in non-metastatic cells 1 protein (NM23A) (nucleoside diphosphate kinase); expressed in non-metastatic cells 1, protein; expressed in non-metastatic cells 1, protein (NM23A) (nucleoside diphosphate kinase); GAAD; Granzyme A activated DNase (GAAD); Granzyme A-activated DNase; GZMA activated DNase; included; metastasis inhibition factor NM23; NB; NBR-A; NBR-B; NBS; NDK A; NDK A 1; NDK A 2; NDK NBR-A; NDK NBR-B; NDKA; NDP kinase A; NDP kinase A 1; NDP kinase A 2; NDP kinase beta; NDP kinase NBR-A; NDPKA; NDPK-A; NM23; NM23A; NM23-C1; NM23-H1; NM23H1B; nm23-M1; NME/NM23 nucleoside diphosphate kinase 1; Nme1; NME1-1; NME1-NME2 spliced read-through transcript; non-metastatic cells 1, protein (NM23A) expressed in; nucleoside diphosphate kinase A; nucleoside diphosphate kinase A 1; nucleoside diphosphate kinase A 2; nucleoside diphosphate kinase NBR-B; nucleoside-diphosphate kinase 1; nuc
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4830
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
NME1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P15531
Gene Symbols:
NME1
Immunogen:
Recombinant Human NME1/NDKA protein (Ala2-Glu152)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry
Clone:
01
Conjugate:
Unconjugated
Gene:
NME1
Gene Alias:
AL024257; AWD; expressed in non-metastatic cells 1; expressed in non-metastatic cells 1 protein; expressed in non-metastatic cells 1 protein (NM23A) (nucleoside diphosphate kinase); expressed in non-metastatic cells 1, protein; expressed in non-metastatic cells 1, protein (NM23A) (nucleoside diphosphate kinase); GAAD; Granzyme A activated DNase (GAAD); Granzyme A-activated DNase; GZMA activated DNase; included; metastasis inhibition factor NM23; NB; NBR-A; NBR-B; NBS; NDK A; NDK A 1; NDK A 2; NDK NBR-A; NDK NBR-B; NDKA; NDP kinase A; NDP kinase A 1; NDP kinase A 2; NDP kinase beta; NDP kinase NBR-A; NDPKA; NDPK-A; NM23; NM23A; NM23-C1; NM23-H1; NM23H1B; nm23-M1; NME/NM23 nucleoside diphosphate kinase 1; Nme1; NME1-1; NME1-NME2 spliced read-through transcript; non-metastatic cells 1, protein (NM23A) expressed in; nucleoside diphosphate kinase A; nucleoside diphosphate kinase A 1; nucleoside diphosphate kinase A 2; nucleoside diphosphate kinase NBR-B; nucleoside-diphosphate kinase 1; nuc
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4830
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid