PIMA529799

PEDF Recombinant Rabbit Monoclonal Antibody (061), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA529799-Each-of-1 In Stock ₹ 39,785.40

PIMA529799 - Each of 1

₹ 39,785.40

In Stock

Quantity

1

Base Price: ₹ 39,785.40

GST (18%): ₹ 7,161.372

Total Price: ₹ 46,946.772

Antigen

PEDF

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

0

Gene Symbols

SERPINF1

Immunogen

Recombinant Rat SerpinF1/PEDF Protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG

Applications

ELISA

Clone

061

Conjugate

Unconjugated

Gene

SERPINF1

Gene Alias

AI195227; alpha-2 antiplasmin; caspin; Cell proliferation-inducing gene 35 protein; Dmrs91; EPC 1; EPC1; EPC-1; OI12; OI6; PEDF; Pedfl; PIG 35; PIG35; pigment epithelium derived factor; pigment epithelium-derived factor; Sdf3; SDF-3; serine (or cysteine) peptidase inhibitor, clade F, member 1; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serine (or cysteine) proteinase inhibitor, clade F), member 1; serine (or cysteine) proteinase inhibitor, clade F, member 1; serpin F1; serpin family F member 1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serpin peptidase inhibitor, clade F, member 1; SERPINF 1; Serpinf1; serpin-F1; sserpin family F member 1; stromal cell derived factor 3; stromal cell-derived factor 3; testis tissue sperm-binding protein Li 70n

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

287526

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • This antibody has specificity for Rat SerpinF1/PEDF
  • PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties
  • It is a 50 kDa glycoprotein produced and secreted in many tissues throughout the body
  • A major component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells
  • In addition, PEDF is able to inhibit the activity of angiogenic factors, such as VEGF and FGF-2
  • The neuroprotective effects of PEDF are achieved through suppression of neuronal apoptosis induced by peroxide, glutamate, or other neurotoxins
  • The recent identification of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity (1) should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin
  • To date, PEDF-R is the only signaling receptor known to be used by a serpin family member
  • The unique range of PEDF activities implicate it as a potential therapeutic agent for the treatment of vasculature-related neurodegenerative diseases, such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR)
  • PEDF also has the potential to be useful in the treatment of various angiogenesis-related diseases including a number of cancers.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA529799

--


Antigen:
PEDF

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
0

Gene Symbols:
SERPINF1

Immunogen:
Recombinant Rat SerpinF1/PEDF Protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA

Clone:
061

Conjugate:
Unconjugated

Gene:
SERPINF1

Gene Alias:
AI195227; alpha-2 antiplasmin; caspin; Cell proliferation-inducing gene 35 protein; Dmrs91; EPC 1; EPC1; EPC-1; OI12; OI6; PEDF; Pedfl; PIG 35; PIG35; pigment epithelium derived factor; pigment epithelium-derived factor; Sdf3; SDF-3; serine (or cysteine) peptidase inhibitor, clade F, member 1; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serine (or cysteine) proteinase inhibitor, clade F), member 1; serine (or cysteine) proteinase inhibitor, clade F, member 1; serpin F1; serpin family F member 1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serpin peptidase inhibitor, clade F, member 1; SERPINF 1; Serpinf1; serpin-F1; sserpin family F member 1; stromal cell derived factor 3; stromal cell-derived factor 3; testis tissue sperm-binding protein Li 70n

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
287526

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA529801

--


Antigen:
Neuroserpin

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q99574

Gene Symbols:
Serpini1

Immunogen:
Recombinant Human SerpinI1 protein (Met1-Leu410)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA

Clone:
001

Conjugate:
Unconjugated

Gene:
Serpini1

Gene Alias:
AI837402; DKFZp781N13156; neuroserpin; Ns; Peptidase inhibitor 12; PI12; PI-12; protease inhibitor 17; raPIT5a; serine (or cysteine) peptidase inhibitor, clade I, member 1; serine (or cysteine) proteinase inhibitor clade member 1; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; serine protease inhibitor 17; serpin family I member 1; serpin I1; serpin peptidase inhibitor clade I member 1; serpin peptidase inhibitor, clade I (neuroserpin), member 1; serpin peptidase inhibitor, clade I, member 1; SERPINI1; Spi17

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5274

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA529802

--


Antigen:
Neuroserpin

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O35684

Gene Symbols:
Serpini1

Immunogen:
Recombinant Mouse SerpinI1 protein (Met1-Leu410)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA

Clone:
009

Conjugate:
Unconjugated

Gene:
Serpini1

Gene Alias:
AI837402; DKFZp781N13156; neuroserpin; Ns; Peptidase inhibitor 12; PI12; PI-12; protease inhibitor 17; raPIT5a; serine (or cysteine) peptidase inhibitor, clade I, member 1; serine (or cysteine) proteinase inhibitor clade member 1; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; serine protease inhibitor 17; serpin family I member 1; serpin I1; serpin peptidase inhibitor clade I member 1; serpin peptidase inhibitor, clade I (neuroserpin), member 1; serpin peptidase inhibitor, clade I, member 1; SERPINI1; Spi17

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20713

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA529804

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Antigen:
SFTPD

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P50404

Gene Symbols:
SFTPD

Immunogen:
Recombinant Mouse SFTPD/SP-D/SFTP4 protein (Met1-Phe374)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Clone:
119

Conjugate:
Unconjugated

Gene:
SFTPD

Gene Alias:
AI573415; COLEC7; Collectin7; collectin-7; CP4; EGK_19692; Lung surfactant protein D; PSPD; PSP-D; PSP-D Surfactant protein D; pulmonary surfactant apoprotein; Pulmonary surfactant associated protein PSP-D; pulmonary surfactant protein D; pulmonary surfactant-associated protein D; SFTP 4; Sftp4; SFTPD; SPD; SP-D; surfactant associated protein D; Surfactant associated protein pulmonary 4; surfactant protein D; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20390

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid