PIMA530803

PTS Monoclonal Antibody (02), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA530803-Each-of-1 In Stock ₹ 31,229.40

PIMA530803 - Each of 1

₹ 31,229.40

In Stock

Quantity

1

Base Price: ₹ 31,229.40

GST (18%): ₹ 5,621.292

Total Price: ₹ 36,850.692

Antigen

PTS

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q03393

Gene Symbols

Pts

Immunogen

Recombinant Human PTS Protein (Met1-Glu145)

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA

Clone

02

Conjugate

Unconjugated

Gene

Pts

Gene Alias

6-pyruvoyl tetrahydrobiopterin synthase; 6-pyruvoyltetrahydropterin synthase; 6-pyruvoyl-tetrahydropterin synthase; PTP synthase; PTPS; PTS

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5805

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Human PTS
  • The tetrahydrobiopterin (BH4) cofactor is essential for hepatic hydroxylase, which is involved in phenylalanine degradation and catecholamine and serotonin biosynthesis
  • BH4 is also an essential and limiting cofactor for all types of nitric oxide synthase
  • BH4 deficiency results in hyperphenylalaninemia and monoamine neurotransmitter depletion and is most commonly due to autosomal recessive mutation in 6-pyruvoyltetrahydropterin synthase (PTPS), the second enzyme for BH4 biosynthesis
  • The active site of PTPS consists of the pterin-anchoring Glu A107 neighbored by two catalytic motifs: a Zn(II) binding site and an inter-subunit catalytic triad formed by Cys A42, Asp B88 and His B89
  • The active site of PTPS undergoes a Zn and Mg-dependent reaction that includes a triphosphate elimination, a stereospecific reduction and the oxidation of both side hydroxyl groups
  • The catalytic triad of PTPS is involved in the deprotonation of the side-chain carbons of substrates
  • In addition, Ser 19 of human PTPS may be a substrate for cGMP-dependent protein kinase type II phosphorylation in vivo, which is essential for normal activity of PTPS.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA530803

--


Antigen:
PTS

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q03393

Gene Symbols:
Pts

Immunogen:
Recombinant Human PTS Protein (Met1-Glu145)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA

Clone:
02

Conjugate:
Unconjugated

Gene:
Pts

Gene Alias:
6-pyruvoyl tetrahydrobiopterin synthase; 6-pyruvoyltetrahydropterin synthase; 6-pyruvoyl-tetrahydropterin synthase; PTP synthase; PTPS; PTS

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5805

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA530804

--


Antigen:
IL-21

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9ES17

Gene Symbols:
IL21

Immunogen:
Recombinant Mouse IL-21 Protein (Pro25-Ser146)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA

Clone:
012

Conjugate:
Unconjugated

Gene:
IL21

Gene Alias:
CVID11, CX2, il 21, IL21, IL-21, ILN, Interleukin, interleukin 21, Interleukin21, interleukin-21, interleukin-21 isoform, porcine interleukin-21, Za11

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
60505

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA530805

--


Antigen:
REG1A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P05451

Gene Symbols:
REG1A

Immunogen:
Recombinant Human REG1A Protein (Met1-Asn166)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA

Clone:
09

Conjugate:
Unconjugated

Gene:
REG1A

Gene Alias:
ICRF; islet cells regeneration factor; Islet of Langerhans regenerating protein; LITHOST; Lithostathine; lithostathine 1 alpha; lithostathine-1-alpha; MGC12447; P19; pancreatic stone protein; pancreatic stone protein, secretory; pancreatic thread protein; protein-X; PSP; PSPS; PSPS1; PTP; RATLITHOST; RATRGPI; Reg; Reg1; REG1A; REG-1-alpha; regenerating family member 1 alpha; regenerating islet-derived 1 alpha; regenerating islet-derived mouse homolog 1; regenerating islet-derived protein 1-alpha; Regenerating protein I alpha; regeneration protein, lithostatin, pancreatic stone protein; Rgp1; RGPI

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5967

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA530806

--


Antigen:
REG1B

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P48304

Gene Symbols:
REG1B

Immunogen:
Recombinant Human REG1B Protein (Met1-Asn166)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA

Clone:
008

Conjugate:
Unconjugated

Gene:
REG1B

Gene Alias:
lithostathine 1 beta; lithostathine-1-beta; Pancreatic stone protein 2; PSP-2; PSPS2; REG1B; REG-1-beta; regenerating family member 1 beta; regenerating islet-derived 1 beta; regenerating islet-derived 1 beta (pancreatic stone protein, pancreatic thread protein); regenerating islet-derived protein 1-beta; Regenerating protein I beta; REGH; REGI-BETA; REGL; secretory pancreatic stone protein 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5968

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid