PIMA530813
IL-22 Monoclonal Antibody (04), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530813-Each-of-1 | In Stock | ₹ 31,143.84 |
PIMA530813 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,143.84
GST (18%): ₹ 5,605.891
Total Price: ₹ 36,749.731
Antigen
IL-22
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q9GZX6
Gene Symbols
IL22
Immunogen
Recombinant Human IL22/Interleukin 22 Protein (Ala34-Ile179)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG3
Applications
ELISA
Clone
04
Conjugate
Unconjugated
Gene
IL22
Gene Alias
Cytokine Zcyto18; EGK_03903; il 22; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL22; IL-22; Il22a; IL-22a; IL-D110; ILN; ILTIF; IL-TIF; ILTIF alpha; IL-TIF alpha; ILTIFa; Interleukin; interleukin 10-related T cell-derived inducible factor; interleukin 22; Interleukin22; interleukin-22; Interleukin-22a; RGD1561292; TIFa; TIFIL-23; UNQ3099/PRO10096; ZCYTO18
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
50616
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- This antibody has specificity for Human IL22/Interleukin 22
- IL-22 also known as IL-10-related T-cell derived inducible factor, is an alpha helical cytokine and is considered a member of the IFN-IL-10 family, which includes IL-19, IL-20, IL-24, IL-26, IL-28, IL-29, and the type I and II interferons
- IL-22 is produced mainly by activated T cells and NK cells
- In humans, the IL-22 gene is located on the q arm of chromosome 12, and is structurally related to IL10
- IL-22 acts by engaging the heterodimeric receptor complex consisting of primary receptor IL-22R1 and accessory receptor IL-10R2
- IL-22R1 also binds IL-20 and IL-24; IL-10R2 also binds IL-10, IL-27, IL-28, and IL-29
- Binding of IL-22 to its receptor complex induces signal transduction, particularly via the JAK-STAT pathway
- In addition to the membrane-bound IL-22R1/IL-10R2 complex, a soluble single-chain IL-22 receptor termed IL-22BP has been found to antagonize IL-22 binding and signaling
- IL-22 appears not to directly influence immune cells, and major targets of the cytokine appear to be nonimmune cells, such as cells of the skin, digestive and respiratory system, as well as hepatocytes, and keratinocytes
- IL-22 has been described as an effector cytokine of the Th17 lineage
- Along with IL-17A and IL-17F, IL-22 regulates genes associated with innate immunity of the skin
- IL-17A, IL-17F and IL-22 are all co-expressed by Th17 cells, however, they are differentially regulated
- The effects of IL-22 include induction of acute phase reactants and antimicrobial proteins, as well as increasing the mobility of keratinocytes
- IL-22 is highly expressed during chronic inflammation, and found to activate intracellular kinases and transcription factors
- IL-22 is critical for host defense against infections of extracellular pathogens, and promotes wound-healing responses
- IL-22 is upregulated in activated T cells
- IL-22 has been reported to mediate IL-23-induced acanthosis and dermal inflammation through activation of STAT3.
Compare Similar Items
Show Difference
Antigen: IL-22
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q9GZX6
Gene Symbols: IL22
Immunogen: Recombinant Human IL22/Interleukin 22 Protein (Ala34-Ile179)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG3
Applications: ELISA
Clone: 04
Conjugate: Unconjugated
Gene: IL22
Gene Alias: Cytokine Zcyto18; EGK_03903; il 22; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL22; IL-22; Il22a; IL-22a; IL-D110; ILN; ILTIF; IL-TIF; ILTIF alpha; IL-TIF alpha; ILTIFa; Interleukin; interleukin 10-related T cell-derived inducible factor; interleukin 22; Interleukin22; interleukin-22; Interleukin-22a; RGD1561292; TIFa; TIFIL-23; UNQ3099/PRO10096; ZCYTO18
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 50616
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
IL-22
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q9GZX6
Gene Symbols:
IL22
Immunogen:
Recombinant Human IL22/Interleukin 22 Protein (Ala34-Ile179)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG3
Applications:
ELISA
Clone:
04
Conjugate:
Unconjugated
Gene:
IL22
Gene Alias:
Cytokine Zcyto18; EGK_03903; il 22; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL22; IL-22; Il22a; IL-22a; IL-D110; ILN; ILTIF; IL-TIF; ILTIF alpha; IL-TIF alpha; ILTIFa; Interleukin; interleukin 10-related T cell-derived inducible factor; interleukin 22; Interleukin22; interleukin-22; Interleukin-22a; RGD1561292; TIFa; TIFIL-23; UNQ3099/PRO10096; ZCYTO18
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
50616
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: RhoA
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P61586
Gene Symbols: RHOA
Immunogen: Recombinant Human RhoA protein (Met1-Leu193)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA
Clone: 101
Conjugate: Unconjugated
Gene: RHOA
Gene Alias: Aplysia ras-related homolog 12; Aplysia RAS-related homolog 6; aplysia ras-related homolog A; aplysia ras-related homolog A1; aplysia ras-related homolog A2; ARH12; ARH6; ARH9; ARHA; Arha1; Arha2; ARHB; ARHC; h12; h6; H9; MGC72339; MST081; MSTP081; oncogene RHO H12; oncogene RHO H6; oncogene RHO H9; plysia ras-related homolog A2; Ras family member A; ras homolog A1; ras homolog A2; ras homolog family member A; ras homolog family member B; ras homolog family member C; ras homolog gene family, member A; ras homolog gene family, member A1; ras homolog gene family, member A2; ras homolog gene family, member B; ras homolog gene family, member C; RAS-related homolog 9; Rho; Rho cDNA clone 12; Rho cDNA clone 6; rho cDNA clone 9; Rho family GTPase; RHO12; Rhoa; RHOB; RHOC; rhoC GTPase; RHOH12; RHOH6; RHOH9; rho-related GTP-binding protein RhoB; Rho-related GTP-binding protein RhoC; small GTP binding protein RhoA; small GTP binding protein RhoC; transforming protein RhoA
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 387
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RhoA
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P61586
Gene Symbols:
RHOA
Immunogen:
Recombinant Human RhoA protein (Met1-Leu193)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA
Clone:
101
Conjugate:
Unconjugated
Gene:
RHOA
Gene Alias:
Aplysia ras-related homolog 12; Aplysia RAS-related homolog 6; aplysia ras-related homolog A; aplysia ras-related homolog A1; aplysia ras-related homolog A2; ARH12; ARH6; ARH9; ARHA; Arha1; Arha2; ARHB; ARHC; h12; h6; H9; MGC72339; MST081; MSTP081; oncogene RHO H12; oncogene RHO H6; oncogene RHO H9; plysia ras-related homolog A2; Ras family member A; ras homolog A1; ras homolog A2; ras homolog family member A; ras homolog family member B; ras homolog family member C; ras homolog gene family, member A; ras homolog gene family, member A1; ras homolog gene family, member A2; ras homolog gene family, member B; ras homolog gene family, member C; RAS-related homolog 9; Rho; Rho cDNA clone 12; Rho cDNA clone 6; rho cDNA clone 9; Rho family GTPase; RHO12; Rhoa; RHOB; RHOC; rhoC GTPase; RHOH12; RHOH6; RHOH9; rho-related GTP-binding protein RhoB; Rho-related GTP-binding protein RhoC; small GTP binding protein RhoA; small GTP binding protein RhoC; transforming protein RhoA
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
387
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: RNase1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P07998
Gene Symbols: RNASE1
Immunogen: Recombinant Human RNase A/Ribonuclease A/RNASE1 protein (Met1-Thr156)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA
Clone: 02
Conjugate: Unconjugated
Gene: RNASE1
Gene Alias: AI574248; HP-RNase; RAC1; Rib 1; RIB1; Rib-1; Ribonuclease 1; ribonuclease 1, pancreatic; ribonuclease A; ribonuclease A (pancreatic); ribonuclease A C1; ribonuclease A family member 1, pancreatic; ribonuclease BS-1; Ribonuclease pancreatic; ribonuclease, RNase A family, 1 (pancreatic); RNase 1; RNase A; RNase upI-1; RNASE1; RNAseA; RNS1; Seminal ribonuclease; seminal RNase; seminal RNase (aa 47-124); SRN; S-RNase
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6035
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RNase1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P07998
Gene Symbols:
RNASE1
Immunogen:
Recombinant Human RNase A/Ribonuclease A/RNASE1 protein (Met1-Thr156)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA
Clone:
02
Conjugate:
Unconjugated
Gene:
RNASE1
Gene Alias:
AI574248; HP-RNase; RAC1; Rib 1; RIB1; Rib-1; Ribonuclease 1; ribonuclease 1, pancreatic; ribonuclease A; ribonuclease A (pancreatic); ribonuclease A C1; ribonuclease A family member 1, pancreatic; ribonuclease BS-1; Ribonuclease pancreatic; ribonuclease, RNase A family, 1 (pancreatic); RNase 1; RNase A; RNase upI-1; RNASE1; RNAseA; RNS1; Seminal ribonuclease; seminal RNase; seminal RNase (aa 47-124); SRN; S-RNase
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6035
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: RNF43
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q68DV7
Gene Symbols: RNF43
Immunogen: Recombinant Human RNF43 Protein (Met1-Tyr197)
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA
Clone: 06
Conjugate: Unconjugated
Gene: RNF43
Gene Alias: 4732452J19Rik; E3 ubiquitin-protein ligase RNF43; RGD1305204; RING finger protein 43; RING-type E3 ubiquitin transferase RNF43; RNF124; Rnf43; URCC
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 54894
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RNF43
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q68DV7
Gene Symbols:
RNF43
Immunogen:
Recombinant Human RNF43 Protein (Met1-Tyr197)
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA
Clone:
06
Conjugate:
Unconjugated
Gene:
RNF43
Gene Alias:
4732452J19Rik; E3 ubiquitin-protein ligase RNF43; RGD1305204; RING finger protein 43; RING-type E3 ubiquitin transferase RNF43; RNF124; Rnf43; URCC
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
54894
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid