PIMA530946
KChIP3 Recombinant Rabbit Monoclonal Antibody (011), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530946-Each-of-1 | In Stock | ₹ 39,785.40 |
PIMA530946 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,785.40
GST (18%): ₹ 7,161.372
Total Price: ₹ 46,946.772
Antigen
KChIP3
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q9Y2W7
Gene Symbols
Kcnip3
Immunogen
Recombinant Human CSEN/calsenilin/KCNIP3 Protein (Met1-Ile256)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA
Clone
011
Conjugate
Unconjugated
Gene
Kcnip3
Gene Alias
4933407H12Rik; AI413860; A-type potassium channel modulating protein 3; A-type potassium channel modulatory protein 3; Calsenilin; calsenilin presenilin-binding protein EF hand transcription factor; calsenilin, presenilin binding protein, EF hand transcription factor; calsenilin, presenilin-binding protein, EF hand transcription fa; calsenilin, presenilin-binding protein, EF hand transcription factor; CSEN; downstream regulatory element-antagonist modulator; DREAM; DRE-antagonist modulator; KChIP3; KCNIP3; Kv channel interacting protein 3; Kv channel interacting protein 3, calsenilin; kv channel-interacting protein 3; potassium channel interacting protein 3; potassium voltage-gated channel interacting protein 3; R74849; rKChIP3
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
30818
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human CSEN/calsenilin/KCNIP3
- Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system
- In the heart, Kv4 channels are involved in the repolarization phase of the action potential
- In the brain however, these channels prevent reverse-propagation of action potentials
- Found associated with Kv4 channels are a group of calcium-binding proteins termed KChIPs (Kv channel interacting proteins)
- KChIPs are small molecular weight proteins that bind to the cytoplasmic amino termini of Kv4 alpha-subunits and help to modulate its function
- There are currently three known KChIPs; KChIP1 expressed in the brain; KChIP2 expressed in the brain, heart, and lung, and has three isoforms, a, b, and c; and KChIP3, also known as calsenilin and DREAM (downstream regulatory elements (DRE)-antagonist modulator) which is expressed in the brain and testis
- KChIP3 has activities beyond the modulation of Kv4 currents
- It has been shown that KChIP3 binds to the regulatory DRE and represses transcription from the early-response gene c-fos
- Thus, KCHiP3 is the first known calcium-binding protein to function as a DNA-binding transcriptional regulator
- KChIP3 is also found associated with the presenilins and is implicated in the mediation of beta-amyloid formation.
Compare Similar Items
Show Difference
Antigen: KChIP3
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q9Y2W7
Gene Symbols: Kcnip3
Immunogen: Recombinant Human CSEN/calsenilin/KCNIP3 Protein (Met1-Ile256)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA
Clone: 011
Conjugate: Unconjugated
Gene: Kcnip3
Gene Alias: 4933407H12Rik; AI413860; A-type potassium channel modulating protein 3; A-type potassium channel modulatory protein 3; Calsenilin; calsenilin presenilin-binding protein EF hand transcription factor; calsenilin, presenilin binding protein, EF hand transcription factor; calsenilin, presenilin-binding protein, EF hand transcription fa; calsenilin, presenilin-binding protein, EF hand transcription factor; CSEN; downstream regulatory element-antagonist modulator; DREAM; DRE-antagonist modulator; KChIP3; KCNIP3; Kv channel interacting protein 3; Kv channel interacting protein 3, calsenilin; kv channel-interacting protein 3; potassium channel interacting protein 3; potassium voltage-gated channel interacting protein 3; R74849; rKChIP3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 30818
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
KChIP3
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q9Y2W7
Gene Symbols:
Kcnip3
Immunogen:
Recombinant Human CSEN/calsenilin/KCNIP3 Protein (Met1-Ile256)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA
Clone:
011
Conjugate:
Unconjugated
Gene:
Kcnip3
Gene Alias:
4933407H12Rik; AI413860; A-type potassium channel modulating protein 3; A-type potassium channel modulatory protein 3; Calsenilin; calsenilin presenilin-binding protein EF hand transcription factor; calsenilin, presenilin binding protein, EF hand transcription factor; calsenilin, presenilin-binding protein, EF hand transcription fa; calsenilin, presenilin-binding protein, EF hand transcription factor; CSEN; downstream regulatory element-antagonist modulator; DREAM; DRE-antagonist modulator; KChIP3; KCNIP3; Kv channel interacting protein 3; Kv channel interacting protein 3, calsenilin; kv channel-interacting protein 3; potassium channel interacting protein 3; potassium voltage-gated channel interacting protein 3; R74849; rKChIP3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
30818
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: TNFRSF11B
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O00300
Gene Symbols: TNFRSF11B
Immunogen: Recombinant Human Osteoprotegerin/TNFRSF11B protein (Met1-Leu401)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA
Clone: 340
Conjugate: Unconjugated
Gene: TNFRSF11B
Gene Alias: LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11B; MGC29565; OCIF; Opg; osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4982
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TNFRSF11B
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O00300
Gene Symbols:
TNFRSF11B
Immunogen:
Recombinant Human Osteoprotegerin/TNFRSF11B protein (Met1-Leu401)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA
Clone:
340
Conjugate:
Unconjugated
Gene:
TNFRSF11B
Gene Alias:
LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11B; MGC29565; OCIF; Opg; osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4982
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SCF
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P21583
Gene Symbols: KITLG
Immunogen: Recombinant Human KITLG/SCF/C-kit ligand Protein (Met1-Ala189)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA
Clone: 23
Conjugate: Unconjugated
Gene: KITLG
Gene Alias: 710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4254
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SCF
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P21583
Gene Symbols:
KITLG
Immunogen:
Recombinant Human KITLG/SCF/C-kit ligand Protein (Met1-Ala189)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA
Clone:
23
Conjugate:
Unconjugated
Gene:
KITLG
Gene Alias:
710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4254
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: SCF
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P21583
Gene Symbols: KITLG
Immunogen: Recombinant Human SCF/C-kit ligand protein (Met1-Ala189)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA
Clone: 004
Conjugate: Unconjugated
Gene: KITLG
Gene Alias: 710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4254
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
SCF
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P21583
Gene Symbols:
KITLG
Immunogen:
Recombinant Human SCF/C-kit ligand protein (Met1-Ala189)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA
Clone:
004
Conjugate:
Unconjugated
Gene:
KITLG
Gene Alias:
710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4254
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid