PIMA531475

5-Methylcytosine Monoclonal Antibody (GT4111), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA531475-Each-of-1 In Stock ₹ 45,646.26

PIMA531475 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

5-Methylcytosine

Classification

Monoclonal

Concentration

1.7 mg/mL

Formulation

PBS with no preservative

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Target Species

Chemical

Product Type

Antibody

Isotype

IgG1

Applications

Dot Blot, Immunohistochemistry (Free Floating), Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation

Clone

GT4111

Conjugate

Unconjugated

Gene Alias

5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3

Immunogen

The immunogen used to generate this antibody corresponds to 5-Methylcytosine/5-mC.

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Target Molecule

Chemical

Description

  • Keep as concentrated solution
  • Positive Control: SH-SY5Y genomic DNA
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription
  • It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated
  • An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes
  • Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.

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Img

Thermo Scientific

PIMA531475

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Antigen:
5-Methylcytosine

Classification:
Monoclonal

Concentration:
1.7 mg/mL

Formulation:
PBS with no preservative

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG1

Applications:
Dot Blot, Immunohistochemistry (Free Floating), Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation

Clone:
GT4111

Conjugate:
Unconjugated

Gene Alias:
5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3

Immunogen:
The immunogen used to generate this antibody corresponds to 5-Methylcytosine/5-mC.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Target Molecule:
Chemical

Img

Thermo Scientific

PIMA531478

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Antigen:
COL11A2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
GT212

Conjugate:
Unconjugated

Gene Alias:
COL11A2; Collagen alpha-2(XI) chain; collagen type XI alpha 2; collagen type XI alpha 2 chain; collagen XI-like; collagen, type XI, alpha 2; DAQB-79P13.8; DFNA13; DFNB53; FBCG2; HGNC:2187; HKE5; PARP; pro-a2 chain of collagen type XI; procollagen, type XI, alpha 2; putative collagen XI; STL3; type XI collagen alpha2 chain

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human COL11A2.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Target Molecule:
__

Img

Thermo Scientific

PIMA531479

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Antigen:
p21

Classification:
Monoclonal

Concentration:
1.45 mg/mL

Formulation:
PBS with no preservative

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
GT1032

Conjugate:
Unconjugated

Gene Alias:
Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human p21 Cip1.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Target Molecule:
__

Img

Thermo Scientific

PIMA531480

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Antigen:
p21

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
GT8611

Conjugate:
Unconjugated

Gene Alias:
Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human p21 Cip1.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Target Molecule:
__