PIMA531516
USP7 Monoclonal Antibody (GT6512), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA531516-Each-of-1 | In Stock | ₹ 46,587.42 |
PIMA531516 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,587.42
GST (18%): ₹ 8,385.736
Total Price: ₹ 54,973.156
Antigen
USP7
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q93009
Gene Symbols
USP7
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human USP7.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
GT6512
Conjugate
Unconjugated
Gene
USP7
Gene Alias
2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
7874
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Description
- Keep as concentrated solution
- Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (93%), Pig (97%), Chicken (93%)
- Positive Control: 293T, A431, HeLa, HepG2
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- USP7 or HAUSP is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates
- Since ubiquitylation (polyubiquitination) is most commonly associated with the stability and degradation of cellular proteins, HAUSP activity generally stabilizes its substrate proteins
- HAUSP is most popularly known as a direct antagonist of Mdm2, the E3 ubiquitin ligase for the tumor suppressor protein, p53
- Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53
- Interestingly, in response to oncogenic insults, HAUSP can deubiquitinate p53 and protect p53 from Mdm2-mediated degradation, indicating that it may possess a tumor suppressor function for the immediate stabilization of p53 in response to stress
- Another important role of HAUSP function involves the oncogenic stabilization of p53
- Oncogenes such as Myc and E1A are thought to activate p53 through a p19 alternative reading frame (p19ARF, also called ARF)-dependent pathway, although some evidence suggests ARF is not essential in this process
- An intriguing possibility is that HAUSP provides an alternative pathway for safeguarding the cell against oncogenic insults.
Compare Similar Items
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Antigen: USP7
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q93009
Gene Symbols: USP7
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human USP7.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: GT6512
Conjugate: Unconjugated
Gene: USP7
Gene Alias: 2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 7874
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
USP7
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q93009
Gene Symbols:
USP7
Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human USP7.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
GT6512
Conjugate:
Unconjugated
Gene:
USP7
Gene Alias:
2210010O09Rik; AA409944; AA617399; AU019296; AW548146; C80752; deubiquitinating enzyme 7; Hausp; Herpes virus-associated ubiquitin-specific protease; herpes-virus-associated ubiquitin-specific protease; herpesvirus-associated ubiquitin-specific protease; mHAUSP; protease; rHAUSP; TEF1; Ubiquitin carboxyl-terminal hydrolase 7; ubiquitin specific peptidase 7; ubiquitin specific peptidase 7 (herpes virus-associated); ubiquitin specific protease 7; ubiquitin specific protease 7 (herpes virus-associated); ubiquitin thioesterase 7; ubiquitin thiolesterase 7; ubiquitin-specific-processing protease 7; UBP; USP7
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
7874
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Golgi protein 58k
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O95954, Q91XD4
Gene Symbols: Ftcd
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human FTCD.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2b
Applications: Immunoprecipitation, Western Blot
Clone: GT575
Conjugate: Unconjugated
Gene: Ftcd
Gene Alias: 58 kDa microtubule-binding protein; Formimidoyltetrahydrofolate cyclodeaminase; formimidoyltransferase cyclodeaminase; Formimidoyltransferase-cyclodeaminase; Formiminotetrahydrofolate cyclodeaminase; formiminotransferase cyclodeaminase; formiminotransferase-cyclodeaminase; FTCD; Glutamate formimidoyltransferase; Glutamate formiminotransferase; Glutamate formyltransferase; I79_006831; LCHC1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 10841, 14317
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Golgi protein 58k
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O95954, Q91XD4
Gene Symbols:
Ftcd
Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human FTCD.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunoprecipitation, Western Blot
Clone:
GT575
Conjugate:
Unconjugated
Gene:
Ftcd
Gene Alias:
58 kDa microtubule-binding protein; Formimidoyltetrahydrofolate cyclodeaminase; formimidoyltransferase cyclodeaminase; Formimidoyltransferase-cyclodeaminase; Formiminotetrahydrofolate cyclodeaminase; formiminotransferase cyclodeaminase; formiminotransferase-cyclodeaminase; FTCD; Glutamate formimidoyltransferase; Glutamate formiminotransferase; Glutamate formyltransferase; I79_006831; LCHC1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
10841, 14317
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: TDG
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P56581, Q13569
Gene Symbols: TDG
Immunogen: Recombinant protein encompassing a sequence within the center region of human TDG.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: GT311
Conjugate: Unconjugated
Gene: TDG
Gene Alias: C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; Tdg; thymine DNA glycosylase; thymine-DNA glycosylase
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 21665, 6996
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TDG
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P56581, Q13569
Gene Symbols:
TDG
Immunogen:
Recombinant protein encompassing a sequence within the center region of human TDG.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
GT311
Conjugate:
Unconjugated
Gene:
TDG
Gene Alias:
C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; Tdg; thymine DNA glycosylase; thymine-DNA glycosylase
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
21665, 6996
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: TDG
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P56581, Q13569
Gene Symbols: TDG
Immunogen: Recombinant protein encompassing a sequence within the center region of human TDG.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: GT1511
Conjugate: Unconjugated
Gene: TDG
Gene Alias: C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; Tdg; thymine DNA glycosylase; thymine-DNA glycosylase
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 114521, 21665, 6996
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TDG
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P56581, Q13569
Gene Symbols:
TDG
Immunogen:
Recombinant protein encompassing a sequence within the center region of human TDG.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
GT1511
Conjugate:
Unconjugated
Gene:
TDG
Gene Alias:
C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; Tdg; thymine DNA glycosylase; thymine-DNA glycosylase
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
114521, 21665, 6996
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid