PIMA531541

LC3B Monoclonal Antibody (GT3612), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA531541-Each-of-1 In Stock ₹ 47,357.46

PIMA531541 - Each of 1

₹ 47,357.46

In Stock

Quantity

1

Base Price: ₹ 47,357.46

GST (18%): ₹ 8,524.343

Total Price: ₹ 55,881.803

Antigen

LC3B

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

A6NCE7, Q9GZQ8

Gene Symbols

MAP1LC3B, MAP1LC3B2

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human LC3B.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Western Blot

Clone

GT3612

Conjugate

Unconjugated

Gene

MAP1LC3B2

Gene Alias

1010001C15Rik; Atg8; ATG8E; ATG8F; ATG8G; Autophagy-related protein LC3 B; autophagy-related ubiquitin-like modifier LC3 B; LC3; LC3 beta; LC3A; LC3B; light chain 3; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; Map1alc3; MAP1BLC3; MAP1LC3; MAP1LC3A; MAP1LC3B; MAP1LC3B2; MAP1LC3B-a; microtubule associated protein 1 light chain 3 beta; microtubule associated protein 1 light chain 3 beta 2; microtubule-associated protein 1 light chain 3; microtubule-associated protein 1 light chain 3 beta; microtubule-associated protein 1 light chain 3 beta 2; microtubule-associated proteins 1A/1B light chain 3; microtubule-associated proteins 1A/1B light chain 3 beta 2; Microtubule-associated proteins 1A/1B light chain 3B; Microtubule-associated proteins 1A/1B light chain 3B-like; Microtubule-associated proteins 1A/1B light chain 3B-like protein; Mpl3; RP11-346K17.1; wu:fb60g11; zbs559; zgc:56434

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

643246, 81631

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Keep as concentrated solution
  • Predicted reactivity: Zebrafish (100%), Japanese Medaka (100%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)
  • Positive Control: LC3B-transfected 293T, HepG2 (3 uM Thapsigargin treated for 12hr), HeLa (50 uM chloroquine treated for 24hr)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • LC3B (Autophagy Marker Light Chain 3B, MAP1A/MAP1B LC3 B) in humans, is encoded by the gene MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B)
  • LC3B is associated with microtubule assembly and important is in neurogenesis
  • Recent studies indicate that LC3B plays a vital role in autophagy, a process that involves the bulk degradation of cytoplasmic component
  • Three human LC3 isoforms undergo post-translational modifications during autophagy
  • Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation
  • Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole)
  • LC3B is a microtubule-associated protein that mediate the physical interactions between microtubules and components of the cytoskeleton
  • LC3B may play a role in processes involving cancer, aging, metabolic and neurodegenerative disorders and cardiovascular/pulmonary diseases.

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Img

Thermo Scientific

PIMA531541

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Antigen:
LC3B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
A6NCE7, Q9GZQ8

Gene Symbols:
MAP1LC3B, MAP1LC3B2

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human LC3B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Western Blot

Clone:
GT3612

Conjugate:
Unconjugated

Gene:
MAP1LC3B2

Gene Alias:
1010001C15Rik; Atg8; ATG8E; ATG8F; ATG8G; Autophagy-related protein LC3 B; autophagy-related ubiquitin-like modifier LC3 B; LC3; LC3 beta; LC3A; LC3B; light chain 3; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; Map1alc3; MAP1BLC3; MAP1LC3; MAP1LC3A; MAP1LC3B; MAP1LC3B2; MAP1LC3B-a; microtubule associated protein 1 light chain 3 beta; microtubule associated protein 1 light chain 3 beta 2; microtubule-associated protein 1 light chain 3; microtubule-associated protein 1 light chain 3 beta; microtubule-associated protein 1 light chain 3 beta 2; microtubule-associated proteins 1A/1B light chain 3; microtubule-associated proteins 1A/1B light chain 3 beta 2; Microtubule-associated proteins 1A/1B light chain 3B; Microtubule-associated proteins 1A/1B light chain 3B-like; Microtubule-associated proteins 1A/1B light chain 3B-like protein; Mpl3; RP11-346K17.1; wu:fb60g11; zbs559; zgc:56434

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
643246, 81631

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531545

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Antigen:
SGTA

Classification:
Monoclonal

Concentration:
1.53 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O43765

Gene Symbols:
SGTA

Immunogen:
The immunogen used to generate this antibody corresponds to human SGTA.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
6A4

Conjugate:
Unconjugated

Gene:
SGTA

Gene Alias:
5330427H01Rik; AI194281; alpha h UBP; alphaSGT; Alpha-SGT; D10Ertd190e; hSGT; protein containing three tetratricopeptide repeats; Sgt; Sgt1; SGTA; small glutamine rich tetratricopeptide repeat containing alpha; small glutamine-rich protein with tetratricopeptide repeats 1; small glutamine-rich tetratricopeptide repeat (TPR) containing protein; small glutamine-rich tetratricopeptide repeat (TPR) containing protein (SGT); small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha; small glutamine-rich tetratricopeptide repeat-containing protein alpha; Stg; UBP; vpu-binding protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6449

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531548

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Antigen:
ACSL4

Classification:
Monoclonal

Concentration:
1.28 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O60488, Q9QUJ7

Gene Symbols:
Acsl4

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Human FACL4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
GT186

Conjugate:
Unconjugated

Gene:
Acsl4

Gene Alias:
9430020A05Rik; Acs4; ACSL4; acyl-CoA synthetase 4; acyl-CoA synthetase long-chain family member 4; Arachidonate--CoA ligase; AU018108; Facl4; fatty acid Coenzyme A ligase, long chain 4; fatty acid-Coenzyme A ligase long chain 4; fatty acid-Coenzyme A ligase, long chain 4; fatty-acid-Coenzyme A ligase, long-chain 4; L MRX63; LACS 4; Lacs4; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 4; long-chain fatty-acid-Coenzyme A ligase 4; long-chain-fatty-acid--CoA ligase 4; mACS4; MRX63; MRX68

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2182, 50790

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531549

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Antigen:
H2AK5ac

Classification:
Monoclonal

Concentration:
0.96 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
C0HKE1, C0HKE3, C0HKE4, C0HKE5, C0HKE6, P04908, P0C0S5, P0C0S6, P0C0S7, P0C0S8, P16104, P20671, P27661, Q00728, Q00729, Q8CGP6, Q96A08, Q96KK5, Q96QV6, Q99878

Gene Symbols:
H2ac1, H2AC11, H2AC12, H2AC13, H2AC14, H2AC4, H2AC7, H2AC8, H2AX, H2AZ1, H2bc1

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histone H2AK5ac (acetyl Lys5).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG3

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
GT1262

Conjugate:
Unconjugated

Gene:
H2AC7

Gene Alias:
1190022L06; Acetyl-Histone H2; Acetyl-Histone H2A K5; Acetyl-Histone H2A Lys5; AW228881; dJ160A22.4; dJ86C11.1; gammaH2ax; H2A 615; H2A GL101; H2A histone family member; H2A histone family member X; H2A histone family member Z; H2A histone family, member A; H2A histone family, member C; H2A histone family, member E; H2A histone family, member G; H2A histone family, member M; H2A histone family, member P; H2A histone family, member X; H2A histone family, member Z; H2A.1; H2A.1b; H2A.2; H2A.3; H2A.X; H2A.z; H2a.z-1; H2A/a; H2A/c; H2A/d; H2A/E; H2A/g; H2A/m; H2A/p; H2A/S; H2a/x; H2A/z; H2a-291A; H2a-53; H2ac11; H2ac13; H2AC15; H2AC16; H2AC17; h2ad; H2ae; H2AFA; H2AFALii; H2AFC; H2AFD; H2AFE; H2AFG; H2AFI; H2AFM; H2AFN; H2AFP; H2afx; H2afz; H2AG; H2AH; h2ai; H2ak; H2AK5ac; H2ALys5ac; H2ax; H2AX histone; H2AZ; H2AZ histone; HIS; Hist1h2aa; HIST1H2AB; Hist1h2ac; HIST1H2AD; Hist1h2ae; HIST1H2AG; HIST1H2AH; Hist1h2ai; HIST1H2AJ; HIST1H2AK; HIST1H2AL; HIST1H2AM; Hist1h2an; Hist1h2ao; Hist1h2ap;

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
15270, 221613, 24828, 24829, 255626, 3012, 3013, 3014, 3015, 319165, 319166, 319167, 319168, 319172, 319174, 319191, 500987, 51788, 58940, 680322, 8329, 8331, 8335, 85235, 8969

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid