PIMA531615
AFAP1L2 Monoclonal Antibody (4E12D7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA531615-Each-of-1 | In Stock | ₹ 47,443.02 |
PIMA531615 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,443.02
GST (18%): ₹ 8,539.744
Total Price: ₹ 55,982.764
Antigen
AFAP1L2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
Q8N4X5
Gene Symbols
AFAP1L2
Immunogen
Purified recombinant fragment of human AFAP1L2 (AA: 674-818) expressed in E. coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Western Blot
Clone
4E12D7
Conjugate
Unconjugated
Gene
AFAP1L2
Gene Alias
actin filament associated protein 1 like 2; actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; Afap1l2; AFAP1-like protein 2; AU041783; C86904; CTB-1144G6.4; CTB-1144G6.6; KIAA1914; mKIAA1914; phosphatidylinositol 3-kinase-associated protein; RGD1310668; XB130
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
84632
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Description
- MA5-31615 has been tested in indirect ELISA
- AFAP1L2, also known as XB130, is structurally similar to actin-filament-associated protein (AFAP), containing several SH2- and SH3-binding motifs, two pleckstrin homology domains, a coiled-coil region, and many potential phosphorylation sites
- It interacts with and is phosphorylated by c-Src tyrosine kinase
- Suppression of AFAP1L2 via siRNA reduced Src activity, IL-8 production, EGF-induced phosphorylation of Akt and GSK3beta, and altered cell cycles in human lung epithelial cells suggesting that AFAP1L2 plays a role as an adaptor in the regulation of Src signal transduction and multiple cellular functions
- Recent experiments have shown that AFAP1L2 is highly expressed in thyroid and is the substrate RET/PTC kinase, a thyroid-specific kinase that plays a pathogenic role in papillary thyroid cancer
- Down-regulation of AFAP1L2 in these cancer cells reduced Akt activity, inhibiting cell-cycle progression and cancer cell survival in suspension, indicating that AFAP1L2 may be a valuable target in thyroid cancer therapy
- At least four isoforms of AFAP1L2 are known to exist.
Compare Similar Items
Show Difference
Antigen: AFAP1L2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q8N4X5
Gene Symbols: AFAP1L2
Immunogen: Purified recombinant fragment of human AFAP1L2 (AA: 674-818) expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Western Blot
Clone: 4E12D7
Conjugate: Unconjugated
Gene: AFAP1L2
Gene Alias: actin filament associated protein 1 like 2; actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; Afap1l2; AFAP1-like protein 2; AU041783; C86904; CTB-1144G6.4; CTB-1144G6.6; KIAA1914; mKIAA1914; phosphatidylinositol 3-kinase-associated protein; RGD1310668; XB130
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 84632
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
AFAP1L2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q8N4X5
Gene Symbols:
AFAP1L2
Immunogen:
Purified recombinant fragment of human AFAP1L2 (AA: 674-818) expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Western Blot
Clone:
4E12D7
Conjugate:
Unconjugated
Gene:
AFAP1L2
Gene Alias:
actin filament associated protein 1 like 2; actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; Afap1l2; AFAP1-like protein 2; AU041783; C86904; CTB-1144G6.4; CTB-1144G6.6; KIAA1914; mKIAA1914; phosphatidylinositol 3-kinase-associated protein; RGD1310668; XB130
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
84632
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: ALDH6A1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q02252
Gene Symbols: ALDH6A1
Immunogen: Purified recombinant fragment of human ALDH6A1 (AA: 1-195) expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 6H9B8
Conjugate: Unconjugated
Gene: ALDH6A1
Gene Alias: 1110038I05Rik; AI314632; aldehyde dehydrogenase 6 family member A1; aldehyde dehydrogenase 6 family, member A1; aldehyde dehydrogenase family 6 member A1; aldehyde dehydrogenase family 6, subfamily A1; Aldh6a1; malonate-semialdehyde dehydrogenase; methylmalonate semialdehyde dehydrogenase; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MGC40271; mitochondrial acylating methylmalonate-semialdehyde dehydrogenase; MMSADHA; Mmsdh; testicular tissue protein Li 122
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4329
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
ALDH6A1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q02252
Gene Symbols:
ALDH6A1
Immunogen:
Purified recombinant fragment of human ALDH6A1 (AA: 1-195) expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
6H9B8
Conjugate:
Unconjugated
Gene:
ALDH6A1
Gene Alias:
1110038I05Rik; AI314632; aldehyde dehydrogenase 6 family member A1; aldehyde dehydrogenase 6 family, member A1; aldehyde dehydrogenase family 6 member A1; aldehyde dehydrogenase family 6, subfamily A1; Aldh6a1; malonate-semialdehyde dehydrogenase; methylmalonate semialdehyde dehydrogenase; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MGC40271; mitochondrial acylating methylmalonate-semialdehyde dehydrogenase; MMSADHA; Mmsdh; testicular tissue protein Li 122
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4329
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: ALDH6A1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q02252
Gene Symbols: ALDH6A1
Immunogen: Purified recombinant fragment of human ALDH6A1 (AA: 1-195) expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 6H9B7
Conjugate: Unconjugated
Gene: ALDH6A1
Gene Alias: 1110038I05Rik; AI314632; aldehyde dehydrogenase 6 family member A1; aldehyde dehydrogenase 6 family, member A1; aldehyde dehydrogenase family 6 member A1; aldehyde dehydrogenase family 6, subfamily A1; Aldh6a1; malonate-semialdehyde dehydrogenase; methylmalonate semialdehyde dehydrogenase; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MGC40271; mitochondrial acylating methylmalonate-semialdehyde dehydrogenase; MMSADHA; Mmsdh; testicular tissue protein Li 122
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4329
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
ALDH6A1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q02252
Gene Symbols:
ALDH6A1
Immunogen:
Purified recombinant fragment of human ALDH6A1 (AA: 1-195) expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
6H9B7
Conjugate:
Unconjugated
Gene:
ALDH6A1
Gene Alias:
1110038I05Rik; AI314632; aldehyde dehydrogenase 6 family member A1; aldehyde dehydrogenase 6 family, member A1; aldehyde dehydrogenase family 6 member A1; aldehyde dehydrogenase family 6, subfamily A1; Aldh6a1; malonate-semialdehyde dehydrogenase; methylmalonate semialdehyde dehydrogenase; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MGC40271; mitochondrial acylating methylmalonate-semialdehyde dehydrogenase; MMSADHA; Mmsdh; testicular tissue protein Li 122
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4329
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: alpha Amylase 1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P0DUB6
Gene Symbols: AMY1A
Immunogen: Purified recombinant fragment of human AMY1A (AA: 172-284) expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Western Blot
Clone: 5G6F7
Conjugate: Unconjugated
Gene: AMY1A
Gene Alias: 1,4-alpha-D-glucan glucanohydrolase 1; alpha amylase 1; alpha-amylase 1; Amy1; Amy-1; Amy1a; Amy-1-a; AMY1B; AMY1C; AMY2A; amylase 1, salivary; amylase, alpha 1A (salivary); amylase, salivary, alpha-1A; C030014B17Rik; glycogenase; PA; salivary alpha-amylase; salivary amylase; salivary amylase alpha 1A; salivary and hepatic alpha-amylase
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 24203, 276
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
alpha Amylase 1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P0DUB6
Gene Symbols:
AMY1A
Immunogen:
Purified recombinant fragment of human AMY1A (AA: 172-284) expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Western Blot
Clone:
5G6F7
Conjugate:
Unconjugated
Gene:
AMY1A
Gene Alias:
1,4-alpha-D-glucan glucanohydrolase 1; alpha amylase 1; alpha-amylase 1; Amy1; Amy-1; Amy1a; Amy-1-a; AMY1B; AMY1C; AMY2A; amylase 1, salivary; amylase, alpha 1A (salivary); amylase, salivary, alpha-1A; C030014B17Rik; glycogenase; PA; salivary alpha-amylase; salivary amylase; salivary amylase alpha 1A; salivary and hepatic alpha-amylase
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
24203, 276
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid