PIMA531715
RIG-I Monoclonal Antibody (4G1B6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA531715-Each-of-1 | In Stock | ₹ 47,614.14 |
PIMA531715 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
RIG-I
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
O95786
Gene Symbols
DDX58
Immunogen
Purified recombinant fragment of human DDX58 (AA: 789-925) expressed in E. coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgM
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone
4G1B6
Conjugate
Unconjugated
Gene
DDX58
Gene Alias
6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
23586
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Description
- MA5-31715 has been tested in indirect ELISA
- Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA
- Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response
- Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles
- RIG-I is activated by dsRNAs without a 5'-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs
- Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and μgtimately activating apoptosis, cytokine signaling, and inflammation
- RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus (3), paromyxoviruses, Japanese encephalitis virus, and West Nile virus
- MicroRNA-146a has been implicated in feedback inhibition of RIG-I-dependant antiviral response by negatively regulating RIG-I targets TRAF6, IRAK1, and IRAK2
- Recent evidence has implicated RIG-I in the detection of cytosolic DNA through RNA polymerase III activity.
Compare Similar Items
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Antigen: RIG-I
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: O95786
Gene Symbols: DDX58
Immunogen: Purified recombinant fragment of human DDX58 (AA: 789-925) expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgM
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone: 4G1B6
Conjugate: Unconjugated
Gene: DDX58
Gene Alias: 6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 23586
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RIG-I
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
O95786
Gene Symbols:
DDX58
Immunogen:
Purified recombinant fragment of human DDX58 (AA: 789-925) expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgM
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
4G1B6
Conjugate:
Unconjugated
Gene:
DDX58
Gene Alias:
6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
23586
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: LGP2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q96C10
Gene Symbols: DHX58
Immunogen: Purified recombinant fragment of human DHX58 (AA: 479-678) expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Western Blot
Clone: 3E11F1
Conjugate: Unconjugated
Gene: DHX58
Gene Alias: B430001I08Rik; D11LGP2; D11lgp2e; DEXH (Asp-Glu-X-His) box polypeptide 58; DEXH-box helicase 58; DHX58; Lgp2; LPG2; ortholog of mouse D11lgp2; probable ATP-dependent helicase LGP2; Probable ATP-dependent RNA helicase DHX58; protein D11Lgp2; Protein D11Lgp2 homolog; RGD1310093; RIG-I-like receptor 3; RIG-I-like receptor Lgp2; RLR; RLR-3; RNA helicase LGP2
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 79132
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
LGP2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q96C10
Gene Symbols:
DHX58
Immunogen:
Purified recombinant fragment of human DHX58 (AA: 479-678) expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Western Blot
Clone:
3E11F1
Conjugate:
Unconjugated
Gene:
DHX58
Gene Alias:
B430001I08Rik; D11LGP2; D11lgp2e; DEXH (Asp-Glu-X-His) box polypeptide 58; DEXH-box helicase 58; DHX58; Lgp2; LPG2; ortholog of mouse D11lgp2; probable ATP-dependent helicase LGP2; Probable ATP-dependent RNA helicase DHX58; protein D11Lgp2; Protein D11Lgp2 homolog; RGD1310093; RIG-I-like receptor 3; RIG-I-like receptor Lgp2; RLR; RLR-3; RNA helicase LGP2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
79132
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: DIS3L2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q8IYB7
Gene Symbols: DIS3L2
Immunogen: Purified recombinant fragment of human DIS3L2 (AA: 27-250) expressed in E. coli.
Quantity: 100μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: 6C7B2
Conjugate: Unconjugated
Gene: DIS3L2
Gene Alias: 4930429A22Rik; 8030493P09Rik; DIS3 like 3'-5' exoribonuclease 2; DIS3 mitotic control homolog (S. cerevisiae)-like 2; DIS3 mitotic control homolog-like 2; DIS3 mitotic control-like 2; Dis3l2; DIS3-like 3'-5' exoribonuclease 2; DIS3-like exonuclease 2; FAM6A; family with sequence similarity 6, member A; hDIS3L2; PRLMNS; RGD1560168
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 129563
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
DIS3L2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q8IYB7
Gene Symbols:
DIS3L2
Immunogen:
Purified recombinant fragment of human DIS3L2 (AA: 27-250) expressed in E. coli.
Quantity:
100μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
6C7B2
Conjugate:
Unconjugated
Gene:
DIS3L2
Gene Alias:
4930429A22Rik; 8030493P09Rik; DIS3 like 3'-5' exoribonuclease 2; DIS3 mitotic control homolog (S. cerevisiae)-like 2; DIS3 mitotic control homolog-like 2; DIS3 mitotic control-like 2; Dis3l2; DIS3-like 3'-5' exoribonuclease 2; DIS3-like exonuclease 2; FAM6A; family with sequence similarity 6, member A; hDIS3L2; PRLMNS; RGD1560168
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
129563
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: DNAL4
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: O96015
Gene Symbols: DNAL4
Immunogen: Purified recombinant fragment of human DNAL4 (AA: 1-105) expressed in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Western Blot
Clone: 3B7B7
Conjugate: Unconjugated
Gene: DNAL4
Gene Alias: D15Ertd424e; DNAL4; Dnalc4; dynein axonemal light chain 4; dynein light chain 4, axonemal; dynein light chain, outer arm 4; dynein, axon, light chain 4; dynein, axonemal, light chain 4; dynein, axonemal, light polypeptide 4; MRMV3; outer arm dynein light chain 4; PIG27; proliferation-inducing gene 27; proliferation-inducing protein 27
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 10126
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
DNAL4
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
O96015
Gene Symbols:
DNAL4
Immunogen:
Purified recombinant fragment of human DNAL4 (AA: 1-105) expressed in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Western Blot
Clone:
3B7B7
Conjugate:
Unconjugated
Gene:
DNAL4
Gene Alias:
D15Ertd424e; DNAL4; Dnalc4; dynein axonemal light chain 4; dynein light chain 4, axonemal; dynein light chain, outer arm 4; dynein, axon, light chain 4; dynein, axonemal, light chain 4; dynein, axonemal, light polypeptide 4; MRMV3; outer arm dynein light chain 4; PIG27; proliferation-inducing gene 27; proliferation-inducing protein 27
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
10126
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid