PIMA531779

IL-28A Monoclonal Antibody (7B9A4), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA531779-Each-of-1 In Stock ₹ 47,614.14

PIMA531779 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

IL-28A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q8IZJ0

Gene Symbols

IFNL2

Immunogen

Purified recombinant fragment of human IL28A (AA: 1-200) expressed in E. coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone

7B9A4

Conjugate

Unconjugated

Gene

IFNL2

Gene Alias

cytokine Zcyto20; EG330496; Ifnl2; IFN-lambda2; IFN-lambda-2; Il28a; IL-28A; ILN; interferon lambda 2; interferon lambda-2; interferon, lambda 2; interferon-lambda 2; interferon-lambda2; Interleukin; interleukin 28A; interleukin 28A (interferon, lambda 2); interleukin-28A; ZCYTO20

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

282616

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • MA5-31779 has been tested in indirect ELISA
  • IL-28A belongs to the IFN lambda family, a novel family of cytokines within the IL-10 superfamily
  • The three members of this family are IL-29 (IFN lambda 1), IL-28A (IFN lambda 2), and IL-28B (IFN lambda 3), and are also known as the type III Interferons.The IFN lambdas signal through a heterodimeric receptor of which one subunit, IL-10R2, is shared with other members of the superfamily
  • The second subunit, IFN lambda R1 or IL-28R alpha, is unique to the IFN lambdas
  • Signaling occurs through the Jak/STAT pathway in a similar manner as the type I IFN (IFN alpha/beta) and activates many of the same genes despite low sequence homology between the cytokines and receptors in the two families
  • Both IFN families display antiviral activity through the induction of antiviral protein production in target cells and the upregulation of MHC class I expression
  • These proteins also exhibit antiproliferative and antitumor effects, making them a possible alternative to IFN alpha cancer therapies
  • Unlike the type I IFN, which are able to stimulate most cells, response to IFN lambda stimulation appears to be limited to dendritic and some tumor cells due to the limited expression of IFN lambda R1
  • Another notable difference is the ability of the IFN lambda stimulation to drive dendritic cells towards the production of CD4+CD25+FoxP3+ regulatory T cells, suggesting a possible immunoregulatory role

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Img

Thermo Scientific

PIMA531779

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Antigen:
IL-28A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q8IZJ0

Gene Symbols:
IFNL2

Immunogen:
Purified recombinant fragment of human IL28A (AA: 1-200) expressed in E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
7B9A4

Conjugate:
Unconjugated

Gene:
IFNL2

Gene Alias:
cytokine Zcyto20; EG330496; Ifnl2; IFN-lambda2; IFN-lambda-2; Il28a; IL-28A; ILN; interferon lambda 2; interferon lambda-2; interferon, lambda 2; interferon-lambda 2; interferon-lambda2; Interleukin; interleukin 28A; interleukin 28A (interferon, lambda 2); interleukin-28A; ZCYTO20

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
282616

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531780

--


Antigen:
IL-28A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q8IZJ0

Gene Symbols:
IFNL2

Immunogen:
Purified recombinant fragment of human IL28A (AA: 1-200) expressed in E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
6H9E6

Conjugate:
Unconjugated

Gene:
IFNL2

Gene Alias:
cytokine Zcyto20; EG330496; Ifnl2; IFN-lambda2; IFN-lambda-2; Il28a; IL-28A; ILN; interferon lambda 2; interferon lambda-2; interferon, lambda 2; interferon-lambda 2; interferon-lambda2; Interleukin; interleukin 28A; interleukin 28A (interferon, lambda 2); interleukin-28A; ZCYTO20

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
282616

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531781

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Antigen:
KBTBD8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q8NFY9

Gene Symbols:
KBTBD8

Immunogen:
Purified recombinant fragment of human KBTBD8 (AA: 264-464) expressed in E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
7G8A6

Conjugate:
Unconjugated

Gene:
KBTBD8

Gene Alias:
AU040152; cb672; EMBL:AAI60902.1, ECO:0000312; kbtbd8; kbtbd8 {ECO:0000312; kelch repeat and BTB (POZ) domain containing 8; kelch repeat and BTB domain containing 8; kelch repeat and BTB domain-containing protein 8; kelch repeat and BTB domain-containing protein 8 {ECO:0000250; KIAA1842; LOW QUALITY PROTEIN: kelch repeat and BTB domain-containing protein 8; mKIAA1842; RGD:1563166}; RGD1563166; SSEC 51; SSEC51; SSEC-51; TAKRP; TA-KRP; T-cell activation kelch repeat protein; UniProtKB:Q8NFY9}; wu:fc57a10; zgc:152950

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
84541

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531783

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Antigen:
KV4.2 (KCND2)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q9NZV8

Gene Symbols:
KCND2

Immunogen:
Purified recombinant fragment of human KCND2 (AA: 27-184) expressed in E. coli.

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
7G6A10

Conjugate:
Unconjugated

Gene:
KCND2

Gene Alias:
AI839615; AW555701; KCND2; KIAA1044; KV4.2; mKIAA1044; MNCb-7013; potassium channel alpha subunit Kv4.2; potassium channel Kv4.2; potassium channel, voltage gated Shal related subfamily D, member 2; potassium channel, voltage-gated Shal-related subfamily D, member 2; potassium voltage gated channel, Shal-related family, member 2; potassium voltage-gated channel subfamily D member 2; potassium voltage-gated channel, Shal-related family, member 2; potassium voltage-gated channel, Shal-related subfamily, member 2; R75121; RK5; Shal1; voltage-gated potassium channel; voltage-gated potassium channel subunit Kv4.2; voltage-sensitive potassium channel

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3751

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid