PIMA531807

NPC1 Monoclonal Antibody (8D10B6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA531807-Each-of-1 In Stock ₹ 48,127.50

PIMA531807 - Each of 1

₹ 48,127.50

In Stock

Quantity

1

Base Price: ₹ 48,127.50

GST (18%): ₹ 8,662.95

Total Price: ₹ 56,790.45

Antigen

NPC1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O15118

Gene Symbols

NPC1

Immunogen

Purified recombinant fragment of human NPC1 (AA: 34-174) expressed in E. coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone

8D10B6

Conjugate

Unconjugated

Gene

NPC1

Gene Alias

A430089E03Rik; C85354; Cdig2; D18Ertd139e; D18Ertd723e; FLJ98532; I79_014078; lcsd; Niemann Pick type C1; Niemann-Pick C disease protein; niemann-Pick C1 protein; Niemann-Pick disease, type C1; Niemann-Pick type C1; Niemann-Pick type C1 protein; nmf164; NPC; NPC intracellular cholesterol transporter 1; NPC1; sphingomyelinosis; spm; truncated Niemann-Pick C1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

4864

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • MA5-31807 has been tested in indirect ELISA
  • Mutations in the Niemann-Pick disease type C1 (NPC1) gene result in a fatal progressive neurodegenerative disorder characterized by an abnormal sequestration of lipids including cholesterol and glycosphingolipids
  • The NPC1 protein is a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain
  • NPC1 transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolyzed and released as free cholesterol
  • NPC1, in addition to FTO, MC4R, and PTER has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations.

Compare Similar Items

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Img

Thermo Scientific

PIMA531807

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Antigen:
NPC1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O15118

Gene Symbols:
NPC1

Immunogen:
Purified recombinant fragment of human NPC1 (AA: 34-174) expressed in E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
8D10B6

Conjugate:
Unconjugated

Gene:
NPC1

Gene Alias:
A430089E03Rik; C85354; Cdig2; D18Ertd139e; D18Ertd723e; FLJ98532; I79_014078; lcsd; Niemann Pick type C1; Niemann-Pick C disease protein; niemann-Pick C1 protein; Niemann-Pick disease, type C1; Niemann-Pick type C1; Niemann-Pick type C1 protein; nmf164; NPC; NPC intracellular cholesterol transporter 1; NPC1; sphingomyelinosis; spm; truncated Niemann-Pick C1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4864

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531809

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Antigen:
PXR

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O75469

Gene Symbols:
NR1I2

Immunogen:
Purified recombinant fragment of human NR1I2 (AA:1-142) expressed in E. coli.

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
6H11D8

Conjugate:
Unconjugated

Gene:
NR1I2

Gene Alias:
BXR; mPXR; Nr1i2; Nuclear receptor subfamily 1 group I member 2; nuclear receptor subfamily 1, group 1, member 2; nuclear receptor subfamily 1, group I, member 2; ONR 1; ONR1; orphan nuclear receptor PAR1; Orphan nuclear receptor PXR; PAR; PAR 1; PAR 2; PAR q; PAR1; PAR2; PARq; pregnane X nuclear receptor variant 2; Pregnane X receptor; pregnane X receptor (nuclear receptor sub family 1, group I, member 2); PRR; PXR; PXR.1; PXR.2; PXR1; SAR; Steroid and xenobiotic receptor; SXR

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
8856

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531810

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Antigen:
NRCAM

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q92823

Gene Symbols:
NRCAM

Immunogen:
Purified recombinant fragment of human NRCAM (AA: 1192-1255) expressed in E. coli.

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
7D8C5

Conjugate:
Unconjugated

Gene:
NRCAM

Gene Alias:
ankyrin-binding cell adhesion molecule NrCAM; Bravo; C030017F07Rik; C130076O07Rik; hBravo; KIAA0343; mBravo; MGC138845; MGC138846; mKIAA0343; neuronal cell adhesion molecule; Neuronal surface protein Bravo; neuron-glia-CAM-related cell adhesion molecule; ng-CAM-related; NgCAM-related cell adhesion molecule; Nr CAM; Nrcam; nr-CAM; rBravo

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4897

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531811

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Antigen:
ONECUT3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O60422

Gene Symbols:
ONECUT3

Immunogen:
Purified recombinant fragment of human ONECUT3 (AA: 350-455) expressed in E. coli.

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
10B2F5

Conjugate:
Unconjugated

Gene:
ONECUT3

Gene Alias:
OC3; OC-3; One cut domain family member 3; one cut domain, family member 3; one cut homeobox 3; Onecut3; Transcription factor ONECUT-3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
390874

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid