PIMA531905

SPHK2 Monoclonal Antibody (3C8D3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA531905-Each-of-1 In Stock ₹ 47,443.02

PIMA531905 - Each of 1

₹ 47,443.02

In Stock

Quantity

1

Base Price: ₹ 47,443.02

GST (18%): ₹ 8,539.744

Total Price: ₹ 55,982.764

Antigen

SPHK2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q9NRA0

Gene Symbols

Sphk2

Immunogen

Synthesized peptide of human SK2 (AA: 36-52).

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone

3C8D3

Conjugate

Unconjugated

Gene

Sphk2

Gene Alias

C76851; SK 2; SK2; SK-2; Sphingosine kinase 2; sphingosine kinase type 2; Sphk2; SPK 2; SPK-2; Spk2, Sk2

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

56848

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • MA5-31905 has been tested in indirect ELISA
  • SPHK2, along with SPHK1, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P)
  • S1P signals through G-protein coupled receptors and controls diverse cellular processes
  • Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer
  • SPHK2 is an important signaling molecule with intra- and extracellular functions and has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis
  • The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors)
  • These receptors couple to multiple G proteins (e.g
  • S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide raange of cellular events including cell motility, survival, apoptosis, migration and cell-cell interaction
  • Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells
  • S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).

Compare Similar Items

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Img

Thermo Scientific

PIMA531905

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Antigen:
SPHK2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q9NRA0

Gene Symbols:
Sphk2

Immunogen:
Synthesized peptide of human SK2 (AA: 36-52).

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
3C8D3

Conjugate:
Unconjugated

Gene:
Sphk2

Gene Alias:
C76851; SK 2; SK2; SK-2; Sphingosine kinase 2; sphingosine kinase type 2; Sphk2; SPK 2; SPK-2; Spk2, Sk2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
56848

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531908

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Antigen:
SLC27A5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q4LDG0, Q9Y2P5

Gene Symbols:
SLC27A5

Immunogen:
Purified recombinant fragment of human SLC27A5 (AA: 508-570 ) expressed in E. coli.

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
9C4D1

Conjugate:
Unconjugated

Gene:
SLC27A5

Gene Alias:
ACSB; ACSVL6; BA-CoA ligase; BACS; BAL; bile acid CoA ligase; bile acid-CoA ligase; Bile acyl-CoA synthetase; cholate--CoA ligase; FACVL3; FATP5; FATP-5; Fatty acid transport protein 5; fatty-acid-Coenzyme A ligase, very long-chain 3; FLJ22987; rBAL-1; Slc27a5; solute carrier family 27 (fatty acid transporter), member 5; solute carrier family 27 member 5; ve; Very long-chain acyl-CoA synthetase homolog 2; very long-chain acyl-CoA synthetase-related protein; very long-chain acyl-Coenzyme A dehydrogenase synthase related; Vlacsr; VLACS-related; VLCSH2; VLCS-H2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10998, 26459

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531909

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Antigen:
SSH1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q8WYL5

Gene Symbols:
SSH1

Immunogen:
Synthesized peptide fragment of human SLINGSHOT-1L (AA: 1032-1044 ) expressed in E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone:
6C11G9

Conjugate:
Unconjugated

Gene:
SSH1

Gene Alias:
hSSH-1L; KIAA1298; Protein phosphatase Slingshot homolog 1; slingshot homolog 1; slingshot protein phosphatase 1; SSH1; SSH1L; SSH-1L; SSH-like protein 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
54434

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531912

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Antigen:
SMARCA1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P28370, Q6PGB8

Gene Symbols:
Smarca1

Immunogen:
Purified recombinant fragment of human SMARCA1 (AA: 933-1070) expressed in E. coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
2H7B9

Conjugate:
Unconjugated

Gene:
Smarca1

Gene Alias:
5730494M04Rik; ATP-dependent helicase SMARCA1; DKFZp686D1623; DNA-dependent ATPase SNF2L; FLJ41547; global transcription activator homologous sequence; hSNF2L; ISWI; nucleosome-remodeling factor subunit SNF2L; NURF140; Probable global transcription activator SNF2L1; RGD1561046; RP3-353H6.2; SMARCA1; SNF2L; SNF2L1; SNF2LB; SNF2-like 1; SNF2L-like protein; SNF2LT; sucrose nonfermenting 2-like protein 1; SWI; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1; SWI2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6594, 93761

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid