PIMA531994

PUMA alpha Recombinant Rabbit Monoclonal Antibody (SR42-09), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA531994-Each-of-1 In Stock ₹ 45,817.38

PIMA531994 - Each of 1

₹ 45,817.38

In Stock

Quantity

1

Base Price: ₹ 45,817.38

GST (18%): ₹ 8,247.128

Total Price: ₹ 54,064.508

Antigen

PUMA alpha

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q80ZG6, Q96PG8, Q99ML1, Q9BXH1

Gene Symbols

BBC3

Immunogen

Synthetic peptide within Human PUMA aa 153-193

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SR42-09

Conjugate

Unconjugated

Gene

BBC3

Gene Alias

BBC3, BCL2 binding component 3, Bcl-2 binding component 3, bcl-2-binding component 3, Bcl-2-binding component 3, isoforms 1/2, Bcl-2-binding component 3, isoforms 3/4, BH3-only, FLJ42994, JFY1, JFY-1, p53 up-regulated modulator of apoptosis, PUMA, PUMA/JFY1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

170770, 27113, 317673

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA532213

--

Img

Thermo Scientific

PIMA532272

--

Img

Thermo Scientific

PIMA532231

--

Img

Thermo Scientific

PIMA532706

--

Img

Thermo Scientific

PIMA532228

--

Img

Thermo Scientific

PIMA532332

--

Img

Thermo Scientific

PIMA532224

--

Img

Thermo Scientific

PIMA532502

--

Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53
  • The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b
  • PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53
  • PUMA may be a direct mediator of p53-induced apoptosis
  • Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA531994

--


Antigen:
PUMA alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q80ZG6, Q96PG8, Q99ML1, Q9BXH1

Gene Symbols:
BBC3

Immunogen:
Synthetic peptide within Human PUMA aa 153-193

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SR42-09

Conjugate:
Unconjugated

Gene:
BBC3

Gene Alias:
BBC3, BCL2 binding component 3, Bcl-2 binding component 3, bcl-2-binding component 3, Bcl-2-binding component 3, isoforms 1/2, Bcl-2-binding component 3, isoforms 3/4, BH3-only, FLJ42994, JFY1, JFY-1, p53 up-regulated modulator of apoptosis, PUMA, PUMA/JFY1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
170770, 27113, 317673

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531995

--


Antigen:
PI3K p55 gamma

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q63789, Q64143, Q92569

Gene Symbols:
Pik3r3

Immunogen:
Synthetic peptide within Human PI 3 Kinase p55 gamma aa 429-461.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SR44-06

Conjugate:
Unconjugated

Gene:
Pik3r3

Gene Alias:
AA414954, p55, p55-GAMMA, p55pik, phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55), phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma, phosphatidylinositol 3-kinase p55 subunit, phosphatidylinositol 3-kinase regulatory subunit gamma, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma), phosphoinositide-3-kinase regulatory subunit 3, phosphoinositide-3-kinase, regulatory subunit 3 (gamma), PI3K regulatory subunit gamma, PI3-kinase p85 subunit gamma, PI3-kinase regulatory subunit gamma, PI3-kinase subunit p55-gamma, Pik3r3, ptdIns-3-kinase p85-gamma, ptdIns-3-kinase regulatory subunit gamma, ptdIns-3-kinase regulatory subunit p55-gamma, RP4-533D7.2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18710, 60664, 8503

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531996

--


Antigen:
IRF1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P10914, P15314, P23570

Gene Symbols:
IRF1

Immunogen:
Recombinant protein within Human IRF1 aa 86-325

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SR44-08

Conjugate:
Unconjugated

Gene:
IRF1

Gene Alias:
AU020929, Interferon regulatory factor 1, interferon regulatory factor 1 isoform +I9, interferon regulatory factor 1 isoform d78, interferon regulatory factor 1 isoform delta4, interferon regulatory factor 1 isoform delta7, IRF1, IRF-1, MAR

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16362, 24508, 3659

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA531997

--


Antigen:
RAB9

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P51151, Q99P75, Q9R0M6

Gene Symbols:
Rab9, Rab9a

Immunogen:
Synthetic peptide within Human Rab9 aa 31-80

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot, Western Blot

Clone:
SR45-05

Conjugate:
Unconjugated

Gene:
Rab9a

Gene Alias:
2410064E05Rik, AI195561, rab9, rab9 GTP-binding protein, RAB9, member RAS oncogene family, Rab9a, rab-9A, RAB9A, member RAS oncogene family, RAB9-like protein, ras-related protein Rab-9A, Sid 99, Sid6061p, Sid99

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
56382, 84589, 9367

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid