PIMA532041
MLH1 Recombinant Rabbit Monoclonal Antibody (SP08-04), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532041-Each-of-1 | In Stock | ₹ 51,036.54 |
PIMA532041 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,036.54
GST (18%): ₹ 9,186.577
Total Price: ₹ 60,223.117
Antigen
MLH1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P40692, P97679, Q9JK91
Gene Symbols
Mlh1
Immunogen
Synthetic peptide within Human MLH1 aa 707-756
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SP08-04
Conjugate
Unconjugated
Gene
Mlh1
Gene Alias
1110035C23Rik, AI317206, AI325952, AI561766, COCA2, colon cancer, nonpolyposis type 2, DNA mismatch repair protein Mlh1, DNA mismatch repair protein Mlh1-like protein, FCC2, hMLH1, HNPCC, HNPCC2, I79_014127, MGC5172, mismatch repair protein 1, MLH1, MLH-1, mutL homolog 1, mutL homolog 1 (E. coli), mutL homolog 1, colon cancer, nonpolyposis type 2, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), mutL protein homolog 1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
17350, 4292, 81685
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- MLH1 is a DNA mismatch repair protein
- The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time
- An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI)
- These defects in DNA repair pathways have been related to human carcinogenesis
- The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC)
- MSHS2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process
- It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.
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Antigen: MLH1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P40692, P97679, Q9JK91
Gene Symbols: Mlh1
Immunogen: Synthetic peptide within Human MLH1 aa 707-756
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SP08-04
Conjugate: Unconjugated
Gene: Mlh1
Gene Alias: 1110035C23Rik, AI317206, AI325952, AI561766, COCA2, colon cancer, nonpolyposis type 2, DNA mismatch repair protein Mlh1, DNA mismatch repair protein Mlh1-like protein, FCC2, hMLH1, HNPCC, HNPCC2, I79_014127, MGC5172, mismatch repair protein 1, MLH1, MLH-1, mutL homolog 1, mutL homolog 1 (E. coli), mutL homolog 1, colon cancer, nonpolyposis type 2, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), mutL protein homolog 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17350, 4292, 81685
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MLH1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P40692, P97679, Q9JK91
Gene Symbols:
Mlh1
Immunogen:
Synthetic peptide within Human MLH1 aa 707-756
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SP08-04
Conjugate:
Unconjugated
Gene:
Mlh1
Gene Alias:
1110035C23Rik, AI317206, AI325952, AI561766, COCA2, colon cancer, nonpolyposis type 2, DNA mismatch repair protein Mlh1, DNA mismatch repair protein Mlh1-like protein, FCC2, hMLH1, HNPCC, HNPCC2, I79_014127, MGC5172, mismatch repair protein 1, MLH1, MLH-1, mutL homolog 1, mutL homolog 1 (E. coli), mutL homolog 1, colon cancer, nonpolyposis type 2, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), mutL protein homolog 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17350, 4292, 81685
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: PHD1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: Q6AYU4, Q91YE2, Q96KS0
Gene Symbols: EGLN2
Immunogen: Recombinant protein within Human PHD1 aa 1-91
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SP00-48
Conjugate: Unconjugated
Gene: EGLN2
Gene Alias: 0610011A13Rik, C85656, egl nine homolog 2, egl-9 family hypoxia inducible factor 2, egl-9 family hypoxia-inducible factor 2, Egln2, EIT6, EIT-6, Estrogen-induced tag 6, falkor, HIF-1alpha prolyl-4-hydroxylase-1, HIF-P4H 1, Hif-p4h-1, HIFPH1, HIF-PH1, HIF-prolyl hydroxylase 1, HPH-1, HPH-3, Hypoxia-inducible factor prolyl hydroxylase 1, Ier4, immediate early response 4, P4H1, Phd1, PHD-1, Prolyl hydroxylase domain-containing protein 1, SM-20
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 112398, 112406, 308457
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
PHD1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
Q6AYU4, Q91YE2, Q96KS0
Gene Symbols:
EGLN2
Immunogen:
Recombinant protein within Human PHD1 aa 1-91
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SP00-48
Conjugate:
Unconjugated
Gene:
EGLN2
Gene Alias:
0610011A13Rik, C85656, egl nine homolog 2, egl-9 family hypoxia inducible factor 2, egl-9 family hypoxia-inducible factor 2, Egln2, EIT6, EIT-6, Estrogen-induced tag 6, falkor, HIF-1alpha prolyl-4-hydroxylase-1, HIF-P4H 1, Hif-p4h-1, HIFPH1, HIF-PH1, HIF-prolyl hydroxylase 1, HPH-1, HPH-3, Hypoxia-inducible factor prolyl hydroxylase 1, Ier4, immediate early response 4, P4H1, Phd1, PHD-1, Prolyl hydroxylase domain-containing protein 1, SM-20
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
112398, 112406, 308457
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: PMS2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P54278
Gene Symbols: PMS2
Immunogen: Synthetic peptide within Human PMS2 aa 1-50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SY08-09
Conjugate: Unconjugated
Gene: PMS2
Gene Alias: AW555130, DNA mismatch repair protein PMS2, H_DJ0042M02.9, HNPCC4, mismatch repair endonuclease PMS2, MLH4, PMS1 homolog 2, mismatch repair protein, PMS1 homolog 2, mismatch repair system component, PMS1 protein homolog 2, PMS2, PMS2 postmeiotic segregation increased 2, PMS2 postmeiotic segregation increased 2 (S. cerevisiae), PMS2CL, PMSL2, postmeiotic segregation increased 2, postmeiotic segregation increased 2 (S. cerevisiae), postmeiotic segregation increased 2 nirs variant 6
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5395
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
PMS2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P54278
Gene Symbols:
PMS2
Immunogen:
Synthetic peptide within Human PMS2 aa 1-50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SY08-09
Conjugate:
Unconjugated
Gene:
PMS2
Gene Alias:
AW555130, DNA mismatch repair protein PMS2, H_DJ0042M02.9, HNPCC4, mismatch repair endonuclease PMS2, MLH4, PMS1 homolog 2, mismatch repair protein, PMS1 homolog 2, mismatch repair system component, PMS1 protein homolog 2, PMS2, PMS2 postmeiotic segregation increased 2, PMS2 postmeiotic segregation increased 2 (S. cerevisiae), PMS2CL, PMSL2, postmeiotic segregation increased 2, postmeiotic segregation increased 2 (S. cerevisiae), postmeiotic segregation increased 2 nirs variant 6
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5395
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: VEGF Receptor 1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P17948, P35969, P53767
Gene Symbols: FLT1
Immunogen: Synthetic peptide within Human VEGF Receptor 1 aa 1-50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SY09-09
Conjugate: Unconjugated
Gene: FLT1
Gene Alias: AI323757, embryonic receptor kinase 2, Emrk2, FLT, FLT1, FLT-1, fms related tyrosine kinase 1, FMS-like tyrosine kinase 1, FMS-related tyrosine kinase 1, Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), FRT, i21, sFlt1, soluble VEGFR 1, sVEGFR 1, Tyrosine-protein kinase FRT, tyrosine-protein kinase receptor FLT, Vascular endothelial growth factor receptor 1, vascular endothelial growth factor receptor-1, vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14254, 2321, 54251
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
VEGF Receptor 1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P17948, P35969, P53767
Gene Symbols:
FLT1
Immunogen:
Synthetic peptide within Human VEGF Receptor 1 aa 1-50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SY09-09
Conjugate:
Unconjugated
Gene:
FLT1
Gene Alias:
AI323757, embryonic receptor kinase 2, Emrk2, FLT, FLT1, FLT-1, fms related tyrosine kinase 1, FMS-like tyrosine kinase 1, FMS-related tyrosine kinase 1, Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), FRT, i21, sFlt1, soluble VEGFR 1, sVEGFR 1, Tyrosine-protein kinase FRT, tyrosine-protein kinase receptor FLT, Vascular endothelial growth factor receptor 1, vascular endothelial growth factor receptor-1, vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14254, 2321, 54251
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid