PIMA532078
CD86 (B7-2) Recombinant Rabbit Monoclonal Antibody (SJ20-00), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532078-Each-of-1 | In Stock | ₹ 44,619.54 |
PIMA532078 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,619.54
GST (18%): ₹ 8,031.517
Total Price: ₹ 52,651.057
Antigen
CD86 (B7-2)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P42081
Gene Symbols
CD86
Immunogen
Synthetic peptide within Human CD86 aa 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Western Blot, Immunofluorescence, Immunohistochemistry, Western Blot
Clone
SJ20-00
Conjugate
Unconjugated
Gene
CD86
Gene Alias
activation B7-2 antigen, B lymphocyte activation antigen B72, B7, B7.2, B70, B7-2, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, Cd28l2, CD28LG2, CD86, CD86 antigen, CD86 antigen (CD28 antigen ligand 2, B7-2 antigen), CD86 antigen precursor, CD86 molecule, CLS1, CTLA-4 counter-receptor B7.2, early T cell costimulatory molecule-1, early T-cell costimulatory molecule 1, Early T-cell co-stimulatory molecule 1, ETC-1, FUN-1, LAB72, Ly58, Ly-58, MB7, MB7-2, membrane glycoprotein, MGC34413, T-lymphocyte activation antigen CD86, TS/A-2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
56822, 942
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- CD86 is one of two ligands (the other CD80) for CTLA4 and CD28
- CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation
- Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance
- CD80 appears to play a role distinct from CD80 in T helper cell differentiation
- CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily
- The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4
- Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell
- Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response
- Alternative splicing results in two transcript variants encoding different isoforms of CD86
- Additional transcript variants have been described for CD86, but their full-length sequences have not been determined
- Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
Compare Similar Items
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Antigen: CD86 (B7-2)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P42081
Gene Symbols: CD86
Immunogen: Synthetic peptide within Human CD86 aa 1-50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Western Blot, Immunofluorescence, Immunohistochemistry, Western Blot
Clone: SJ20-00
Conjugate: Unconjugated
Gene: CD86
Gene Alias: activation B7-2 antigen, B lymphocyte activation antigen B72, B7, B7.2, B70, B7-2, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, Cd28l2, CD28LG2, CD86, CD86 antigen, CD86 antigen (CD28 antigen ligand 2, B7-2 antigen), CD86 antigen precursor, CD86 molecule, CLS1, CTLA-4 counter-receptor B7.2, early T cell costimulatory molecule-1, early T-cell costimulatory molecule 1, Early T-cell co-stimulatory molecule 1, ETC-1, FUN-1, LAB72, Ly58, Ly-58, MB7, MB7-2, membrane glycoprotein, MGC34413, T-lymphocyte activation antigen CD86, TS/A-2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 56822, 942
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD86 (B7-2)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P42081
Gene Symbols:
CD86
Immunogen:
Synthetic peptide within Human CD86 aa 1-50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Western Blot, Immunofluorescence, Immunohistochemistry, Western Blot
Clone:
SJ20-00
Conjugate:
Unconjugated
Gene:
CD86
Gene Alias:
activation B7-2 antigen, B lymphocyte activation antigen B72, B7, B7.2, B70, B7-2, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, Cd28l2, CD28LG2, CD86, CD86 antigen, CD86 antigen (CD28 antigen ligand 2, B7-2 antigen), CD86 antigen precursor, CD86 molecule, CLS1, CTLA-4 counter-receptor B7.2, early T cell costimulatory molecule-1, early T-cell costimulatory molecule 1, Early T-cell co-stimulatory molecule 1, ETC-1, FUN-1, LAB72, Ly58, Ly-58, MB7, MB7-2, membrane glycoprotein, MGC34413, T-lymphocyte activation antigen CD86, TS/A-2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
56822, 942
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: NOTCH1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P46531, Q01705, Q07008
Gene Symbols: Notch1
Immunogen: Synthetic peptide within Human Notch 1 aa 2,481-2,530
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SJ205
Conjugate: Unconjugated
Gene: Notch1
Gene Alias: 9930111A19Rik, AOS5, AOVD1, Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila), hN1, lin-12, major type A protein, Mis6, Motch, Motch A, mT14, N1, neurogenic locus notch homolog protein 1, NEXT, NICD, NOTCH, notch 1, Notch 1 extracellular truncation, Notch 1 intracellular domain, Notch gene homolog 1, Notch homolog 1, translocation-associated, notch receptor 1, Notch1, p300, RP23-306D20.12, RP23-306D20.12-001, Tan1, Translocation-associated notch protein TAN-1, transmembrane receptor Notch1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18128, 25496, 4851
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
NOTCH1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P46531, Q01705, Q07008
Gene Symbols:
Notch1
Immunogen:
Synthetic peptide within Human Notch 1 aa 2,481-2,530
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SJ205
Conjugate:
Unconjugated
Gene:
Notch1
Gene Alias:
9930111A19Rik, AOS5, AOVD1, Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila), hN1, lin-12, major type A protein, Mis6, Motch, Motch A, mT14, N1, neurogenic locus notch homolog protein 1, NEXT, NICD, NOTCH, notch 1, Notch 1 extracellular truncation, Notch 1 intracellular domain, Notch gene homolog 1, Notch homolog 1, translocation-associated, notch receptor 1, Notch1, p300, RP23-306D20.12, RP23-306D20.12-001, Tan1, Translocation-associated notch protein TAN-1, transmembrane receptor Notch1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18128, 25496, 4851
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: APAF1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O14727, O88879
Gene Symbols: APAF1
Immunogen: Synthetic peptide within Human Apaf-1 aa 1-50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SY22-02
Conjugate: Unconjugated
Gene: APAF1
Gene Alias: 6230400I06Rik, APAF1, APAF-1, Apaf1l, apoptotic peptidase activating factor 1, apoptotic protease activating factor 1, apoptotic protease-activating factor 1, CED4, DKFZp781B1145, fog, forebrain overgrowth, KIAA0413, mKIAA0413
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11783, 317
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
APAF1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O14727, O88879
Gene Symbols:
APAF1
Immunogen:
Synthetic peptide within Human Apaf-1 aa 1-50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SY22-02
Conjugate:
Unconjugated
Gene:
APAF1
Gene Alias:
6230400I06Rik, APAF1, APAF-1, Apaf1l, apoptotic peptidase activating factor 1, apoptotic protease activating factor 1, apoptotic protease-activating factor 1, CED4, DKFZp781B1145, fog, forebrain overgrowth, KIAA0413, mKIAA0413
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11783, 317
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Caveolin 2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P51636, Q9WVC3
Gene Symbols: CAV2
Immunogen: Synthetic peptide within Human Caveolin-2 aa 1-50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SY22-05
Conjugate: Unconjugated
Gene: CAV2
Gene Alias: AI447843, CAV, CAV2, caveolae, caveolae protein, 20-kD, caveolin 2, caveolin 2 isoform a and b, caveolin-2, MGC12294, Phospho-CAV2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12390, 858
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Caveolin 2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P51636, Q9WVC3
Gene Symbols:
CAV2
Immunogen:
Synthetic peptide within Human Caveolin-2 aa 1-50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SY22-05
Conjugate:
Unconjugated
Gene:
CAV2
Gene Alias:
AI447843, CAV, CAV2, caveolae, caveolae protein, 20-kD, caveolin 2, caveolin 2 isoform a and b, caveolin-2, MGC12294, Phospho-CAV2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12390, 858
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid