PIMA532170

Cyclophilin B Recombinant Rabbit Monoclonal Antibody (ST05-22), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532170-Each-of-1 In Stock ₹ 44,106.18

PIMA532170 - Each of 1

₹ 44,106.18

In Stock

Quantity

1

Base Price: ₹ 44,106.18

GST (18%): ₹ 7,939.112

Total Price: ₹ 52,045.292

Antigen

Cyclophilin B

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P23284, P24368, P24369

Gene Symbols

PPIB

Immunogen

Synthetic peptide within Human Cyclophilin B aa 171-215

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

ST05-22

Conjugate

Unconjugated

Gene

PPIB

Gene Alias

AA408962, AA553318, AI844835, Cphn2, Cphn-2, cyclophilin B, cyclophilin-like protein, Cyp B, CyP-20b, CYPB, CYP-S1, EC 5.2.1.8, epididymis secretory protein Li 39, HEL-S-39, OI9, Peptidyl-prolyl cis-trans isomerase B, peptidylprolyl isomerase B, peptidylprolyl isomerase B (cyclophilin B), PPIase, PPIase B, Ppib, Rotamase, Rotamase B, S-cyclophilin, S-cyclophylin, SCYLP

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

19035, 5479, 64367

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506
  • Proteins which bind FK506 are termed FK506 Binding Proteins (FKBP's) and those which bind cyclosporin A are called cyclophilins (CyP)
  • Both CyP:CsA and FKBP:FK506 complexes have been shown to inhibit calcineurin, a calcium and calmodulin dependent protein phosphatase which has been implicated as an important signaling enzyme in T-cell activation
  • Thus, providing a possible mechanism of immunosuppression by CsA and FK506
  • Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds
  • As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532170

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Antigen:
Cyclophilin B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P23284, P24368, P24369

Gene Symbols:
PPIB

Immunogen:
Synthetic peptide within Human Cyclophilin B aa 171-215

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ST05-22

Conjugate:
Unconjugated

Gene:
PPIB

Gene Alias:
AA408962, AA553318, AI844835, Cphn2, Cphn-2, cyclophilin B, cyclophilin-like protein, Cyp B, CyP-20b, CYPB, CYP-S1, EC 5.2.1.8, epididymis secretory protein Li 39, HEL-S-39, OI9, Peptidyl-prolyl cis-trans isomerase B, peptidylprolyl isomerase B, peptidylprolyl isomerase B (cyclophilin B), PPIase, PPIase B, Ppib, Rotamase, Rotamase B, S-cyclophilin, S-cyclophylin, SCYLP

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
19035, 5479, 64367

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532173

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Antigen:
Cytokeratin 7

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P08729

Gene Symbols:
KRT7

Immunogen:
Synthetic peptide within Human Cytokeratin 7 aa 18-67

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
ST50-05

Conjugate:
Unconjugated

Gene:
KRT7

Gene Alias:
CK7, CK-7, Cytokeratin 7, cytokeratin-7, D15Wsu77e, K2C7, K7, Kb7, keratin 7, keratin 7, type II, keratin associated protein 7.1, keratin complex 2, basic, gene 7, keratin, 55K type II cytoskeletal, keratin, simple epithelial type I, K7, keratin, type II cytoskeletal 7, Keratin-7, keratin-associated protein 7-1, keratin-associated protein 7-1-like protein, Krt2-7, KRT7, krt7 {ECO:0000250, LOC100755511, LOC100861181, NACHT, LRR and PYD domains-containing protein 3, sarcolectin, SCL, si:ch73-233m11.1, si:ch73-233m11.2, similar to keratin 7, type II keratin Kb7, type II mesothelial keratin K7, type-II keratin Kb7, UniProtKB:P08729}

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3855

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532174

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Antigen:
PGK1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P00558, P09411, P16617

Gene Symbols:
PGK1

Immunogen:
Synthetic peptide within Human PGK1 aa 1-49

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot

Clone:
ST49-07

Conjugate:
Unconjugated

Gene:
PGK1

Gene Alias:
cell migration-inducing gene 10 protein, epididymis secretory sperm binding protein Li 68p, HEL-S-68p, MIG10, OK/SW-cl.110, Pgk, Pgk1, Pgk-1, PGKA, Phosphoglycerate kinase, phosphoglycerate kinase 1, Primer recognition protein 2, PRP 2, YCR012W, YCR12W

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18655, 24644, 5230

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532175

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Antigen:
Phospho-c-Myc (Ser62)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P01106, P01108, P09416

Gene Symbols:
MYC

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser62 of Human c-Myc aa 46-87

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
ST49-08

Conjugate:
Unconjugated

Gene:
MYC

Gene Alias:
AU016757, Avian myelocytomatosis viral (v-myc) oncogene homolog, avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, class E basic helix-loop-helix protein 39, cmyc, c-Myc, c-myc epitope tag, c-myc proto-oncogene, mMyc, MRTL, Myc, Myc protein, Myc proto-oncogene protein, MYC proto-oncogene, bHLH transcription factor, Myc2, MYCC, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene-like protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17869, 24577, 4609

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid