PIMA532325

RARA Recombinant Rabbit Monoclonal Antibody (SN0725), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532325-Each-of-1 In Stock ₹ 45,988.50

PIMA532325 - Each of 1

₹ 45,988.50

In Stock

Quantity

1

Base Price: ₹ 45,988.50

GST (18%): ₹ 8,277.93

Total Price: ₹ 54,266.43

Antigen

RARA

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P10276, P11416

Gene Symbols

RARA

Immunogen

Synthetic peptide within Human Retinoic Acid Receptor alpha aa 1-50

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Western Blot

Clone

SN0725

Conjugate

Unconjugated

Gene

RARA

Gene Alias

Nr1b1, nuclear receptor subfamily 1 group B member 1, nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form, RAR, RAR Alpha, RAR alpha 1, RARA, RAR-alpha, RARalpha1, retinoic acid, retinoic acid nuclear receptor alpha variant 1, retinoic acid nuclear receptor alpha variant 2, retinoic acid receptor, retinoic acid receptor alpha, retinoic acid receptor, alpha, retinoic acid receptor, alpha polypeptide, RRA

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

19401, 5914

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • RARA is a receptor for retinoic acid
  • Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes
  • The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5
  • In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression
  • On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation
  • RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis
  • Has a role in the survival of early spermatocytes at the beginning prophase of meiosis
  • In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes
  • In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function
  • Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5
  • Mediates retinoic acid-induced granulopoiesis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532325

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Antigen:
RARA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P10276, P11416

Gene Symbols:
RARA

Immunogen:
Synthetic peptide within Human Retinoic Acid Receptor alpha aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
SN0725

Conjugate:
Unconjugated

Gene:
RARA

Gene Alias:
Nr1b1, nuclear receptor subfamily 1 group B member 1, nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form, RAR, RAR Alpha, RAR alpha 1, RARA, RAR-alpha, RARalpha1, retinoic acid, retinoic acid nuclear receptor alpha variant 1, retinoic acid nuclear receptor alpha variant 2, retinoic acid receptor, retinoic acid receptor alpha, retinoic acid receptor, alpha, retinoic acid receptor, alpha polypeptide, RRA

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
19401, 5914

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532326

--


Antigen:
Phospho-PKC zeta (Thr560)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P09217, Q02956, Q05513

Gene Symbols:
PRKCZ

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Thr560 of Human PKC zeta aa 531-580

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
SN0753

Conjugate:
Unconjugated

Gene:
PRKCZ

Gene Alias:
14 - 3 - 3 - zeta isoform, 14-3-3-zetaisoform, AI098070, aPKCzeta, atypical protein kinase C, C80388, kinase nPKC-zeta, KPCZ, nPKC-zeta, nPKC-zeta PRKCZ, PKC2, Pkcz, PKC-ZETA, Prkcz, protein kinase C zeta, protein kinase C zeta subspecies, protein kinase C zeta type, protein kinase C, zeta, r14-3-3, R74924, zetaPKC

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18762, 25522, 5590

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532327

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Antigen:
Bcl-10

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O95999

Gene Symbols:
BCL10

Immunogen:
Synthetic peptide within Human Bcl10 aa 198-233

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SN74-04

Conjugate:
Unconjugated

Gene:
BCL10

Gene Alias:
AI132454, B cell CLL/lymphoma 10, B cell leukemia/lymphoma 10, B-cell CLL/lymphoma 10, B-cell leukemia/lymphoma 10, B-cell lymphoma/leukemia 10, BCL10, Bcl-10, BCL10 immune signaling adaptor, C81403, CARD containing molecule enhancing NF-kB, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, cE10, c-E10, CED-3/ICH-1 prodomain homologous E10-like regulator, cellular homolog of vCARMEN, Cellular-E10, CIPER, Clap, hCLAP, IMD37, Mamm, mammalian CARD-containing adapter molecule E10, mCIPER, mCLAP, mE10, OTTHUMP00000011647, OTTHUMP00000036080, RCD, RP11-234D19.2, R-RCD1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8915

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532329

--


Antigen:
CD10

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P07861, P08473, Q61391

Gene Symbols:
Mme

Immunogen:
Synthetic peptide within Human CD10 aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SN75-07

Conjugate:
Unconjugated

Gene:
Mme

Gene Alias:
6030454K05Rik, Atriopeptidase, C85356, CALLA, CD10, CMT2T, common acute lymphoblastic leukemia antigen, common acute lymphocytic leukemia antigen, Enkephalinase, EPN, membrane metallo endopeptidase, membrane metalloendopeptidase, membrane metallo-endopeptidase, membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10), membrane metallo-endopeptidase (neutral endopeptidase/enkephalinase), membrane metallo-endopeptidase variant 1, membrane metallo-endopeptidase variant 2, MME, NEP, neprilysin, neprilysin-390, neprilysin-411, neutral endopeptidase 24.11, SFE, Skin fibroblast elastase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17380, 24590, 4311

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid