PIMA532469

FOXO4 Recombinant Rabbit Monoclonal Antibody (JJ09-11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532469-Each-of-1 In Stock ₹ 44,619.54

PIMA532469 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

FOXO4

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P98177, Q9WVH3

Gene Symbols

FOXO4

Immunogen

Recombinant protein within Human FOXO4 aa 456-505

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot

Clone

JJ09-11

Conjugate

Unconjugated

Gene

FOXO4

Gene Alias

AFX, Afx1, Afxh, AFXzeta, Fkhr3, Fork head domain transcription factor AFX1, forkhead box O4, forkhead box protein O4, forkhead protein, FOXO4, FOXO4b, MGC120490, MLLT7, myeloid/lymphoid or mixed lineage-leukemia translocation to 7 homolog, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to, 7, OTTHUMP00000023497, RGD1561201

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

302415, 4303, 54601

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • FOXO4 (Forkhead box O4) is encoded by the FOXO4 gene located on the X chromosome
  • It is also known as AFX1 or MLLT7 (Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Translocated To, 7) and is a member of the O class of forkhead/ winged helix family of transcription factors along with FOXO1, FOXO3 and FOXO6
  • FOXO4 is abundantly expressed in skeletal muscle and adipose tissue
  • FOXO4 binds to the Insulin Responsive Element (IRE) and activates downstream targets of Insulin/IGF1 signaling such as IGFBP1
  • However, the activation of another downstream target of the Insulin/IGF1 pathway, Akt, leads to phosphorylation of FOXO4 on specific Ser/Thr residues
  • This phosphorylation mediates binding of FOXO4 to 14-3-3 and eventual exit of FOXO4 from the nucleus.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532469

--


Antigen:
FOXO4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P98177, Q9WVH3

Gene Symbols:
FOXO4

Immunogen:
Recombinant protein within Human FOXO4 aa 456-505

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot

Clone:
JJ09-11

Conjugate:
Unconjugated

Gene:
FOXO4

Gene Alias:
AFX, Afx1, Afxh, AFXzeta, Fkhr3, Fork head domain transcription factor AFX1, forkhead box O4, forkhead box protein O4, forkhead protein, FOXO4, FOXO4b, MGC120490, MLLT7, myeloid/lymphoid or mixed lineage-leukemia translocation to 7 homolog, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to, 7, OTTHUMP00000023497, RGD1561201

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
302415, 4303, 54601

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532473

--


Antigen:
HSP27

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P04792, P14602, P42930

Gene Symbols:
HSPB1

Immunogen:
Synthetic peptide within Human Hsp27 aa 127-176

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JJ09-13

Conjugate:
Unconjugated

Gene:
HSPB1

Gene Alias:
27kDa, 28 kDa heat shock protein, CMT2F, DKFZp586P1322, epididymis secretory protein Li 102, estrogen-regulated 24 kDa protein, Growth-related 25 kDa protein, heat shock 25 kDa protein, Heat shock 27 kDa protein, heat shock 27kD protein 1, heat shock 27kDa protein 1, Heat shock protein, heat shock protein 1, heat shock protein 27 kDa beta-1, heat shock protein B1, heat shock protein beta-1, heat shock protein family B (small) member 1, heat shock protein, 25 kDa, heat-shock protein, HEL-S-102, HMN2B, HS, HS.76067, HSP, HSP 25, HSP 27, Hsp25, HSP27, HSP28, HSPB1, p25, Phospho-HSP 27, SRP27, Stress-responsive protein 27, truncated hsp25

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
15507, 24471, 3315

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532474

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Antigen:
Cdc45L

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O75419, Q9Z1X9

Gene Symbols:
Cdc45

Immunogen:
Synthetic protein within Human CDC45 aa 501-544

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JJ091-04

Conjugate:
Unconjugated

Gene:
Cdc45

Gene Alias:
CDC 45, CDC 45L, Cdc45, CDC45 cell division cycle 45 homolog, CDC45 like, CDC45L, CDC45L2, CDC45-related protein, Cell division control protein 45 homolog, cell division cycle 45, cell division cycle 45 homolog, cell division cycle 45-like 2, human CDC45, PORC PI 1, PORC-PI-1, UNQ374/PRO710

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12544, 287961, 8318

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532477

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Antigen:
ZNRF2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q71FD5, Q8NHG8

Gene Symbols:
Znrf2

Immunogen:
Synthetic peptide within Human ZNRF2 aa 162-206

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
JJ0924

Conjugate:
Unconjugated

Gene:
Znrf2

Gene Alias:
1190002C14Rik, AU044205, D6Ertd365e, E3 ubiquitin-protein ligase ZNRF2, protein Ells2, RING finger protein 202, RING-type E3 ubiquitin transferase ZNRF2, RNF202, zinc and ring finger 1, zinc and ring finger 2, zinc and ring finger 2, E3 ubiquitin protein ligase, zinc finger/RING finger 2, zinc/RING finger protein 2, Znrf1, Znrf2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
223082, 362367, 387524

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid