PIMA532520
AGO2 Recombinant Rabbit Monoclonal Antibody (JF0992), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532520-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA532520 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
AGO2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q8CJG0, Q9QZ81, Q9UKV8
Gene Symbols
AGO2
Immunogen
Synthetic peptide within Human Argonaute 2 aa 361-404
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
JF0992
Conjugate
Unconjugated
Gene
AGO2
Gene Alias
1110029L17Rik, 2310051F07Rik, AGO1, AGO2, AI225898, AL022874, argonaute 2, argonaute 2, RISC catalytic component, argonaute RISC catalytic component 2, argonaute RISC catalytic subunit 2, Argonaute1, argonaute2, argonaute2 {ECO:0000255, AW546247, CTA-204B4.6, eIF2C, eIF2C 1, eIF-2C 1, eIF2C 2, eIF-2C 2, eIF2C 2 {ECO:0000255, eIF-2C 2 {ECO:0000255, EIF2C1, Eif2c2, ENSMUSG00000072493, Eukaryotic translation initiation factor 2C 2, eukaryotic translation initiation factor 2C 2 {ECO:0000255, eukaryotic translation initiation factor 2C, 2, GERp95, Gm10365, Golgi ER protein 95 kDa, hAgo1, hAgo2, HAMAP-Rule:MF_03031}, Kiaa4215, mAgo2, mKIAA4215, PAZ Piwi domain protein, Piwi/Argonaute family protein meIF2C2, PPD, Protein argonaute-1, protein argonaute-2, Protein slicer, Q10
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
239528, 27161, 59117
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Ago proteins are broadly expressed in somatic cells, associate with miRNAs and are key actors in different RNA silencing pathways
- However, only the Ago2 protein displays endonucleolytic or "eSlicer"e activity and can therefore execute miRNA-directed cleavage of target mRNA, provided that the base-pairing between the Ago2-associated miRNA and the mRNA sequence is perfect
- In case of partial complementarity, the Ago2 protein fails to cleave, but instead interferes with translation of the target mRNA via its translational repression activity
- Ago2 has been shown to play a non-redundant role in small RNA guided gene silencing processes, including RNA interference, translation repression and heterochromatinization
- As a core element of the RISC complex, AGO2 initiates the degradation of target mRNAs through its catalytic activity in gene silencing processes guided by siRNAs or miRNAs
- In addition to mRNA degradation or gene silencing guided by miRNAs, Ago2 also acts as a RNA slicer in a Dicer-independent way, as well as a regulator of miRNA maturation
- Over-expression of Ago2 has been correlated with several aspects of cancers, including tumor cell growth and the overall survival of cancer patients
- Furthermore, gene disruption in the mouse demonstrated that the Ago2 protein is essential for embryonic development and a key regulator of B-lymphoid and erythroid development.
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Antigen: AGO2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: Q8CJG0, Q9QZ81, Q9UKV8
Gene Symbols: AGO2
Immunogen: Synthetic peptide within Human Argonaute 2 aa 361-404
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: JF0992
Conjugate: Unconjugated
Gene: AGO2
Gene Alias: 1110029L17Rik, 2310051F07Rik, AGO1, AGO2, AI225898, AL022874, argonaute 2, argonaute 2, RISC catalytic component, argonaute RISC catalytic component 2, argonaute RISC catalytic subunit 2, Argonaute1, argonaute2, argonaute2 {ECO:0000255, AW546247, CTA-204B4.6, eIF2C, eIF2C 1, eIF-2C 1, eIF2C 2, eIF-2C 2, eIF2C 2 {ECO:0000255, eIF-2C 2 {ECO:0000255, EIF2C1, Eif2c2, ENSMUSG00000072493, Eukaryotic translation initiation factor 2C 2, eukaryotic translation initiation factor 2C 2 {ECO:0000255, eukaryotic translation initiation factor 2C, 2, GERp95, Gm10365, Golgi ER protein 95 kDa, hAgo1, hAgo2, HAMAP-Rule:MF_03031}, Kiaa4215, mAgo2, mKIAA4215, PAZ Piwi domain protein, Piwi/Argonaute family protein meIF2C2, PPD, Protein argonaute-1, protein argonaute-2, Protein slicer, Q10
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 239528, 27161, 59117
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
AGO2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
Q8CJG0, Q9QZ81, Q9UKV8
Gene Symbols:
AGO2
Immunogen:
Synthetic peptide within Human Argonaute 2 aa 361-404
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
JF0992
Conjugate:
Unconjugated
Gene:
AGO2
Gene Alias:
1110029L17Rik, 2310051F07Rik, AGO1, AGO2, AI225898, AL022874, argonaute 2, argonaute 2, RISC catalytic component, argonaute RISC catalytic component 2, argonaute RISC catalytic subunit 2, Argonaute1, argonaute2, argonaute2 {ECO:0000255, AW546247, CTA-204B4.6, eIF2C, eIF2C 1, eIF-2C 1, eIF2C 2, eIF-2C 2, eIF2C 2 {ECO:0000255, eIF-2C 2 {ECO:0000255, EIF2C1, Eif2c2, ENSMUSG00000072493, Eukaryotic translation initiation factor 2C 2, eukaryotic translation initiation factor 2C 2 {ECO:0000255, eukaryotic translation initiation factor 2C, 2, GERp95, Gm10365, Golgi ER protein 95 kDa, hAgo1, hAgo2, HAMAP-Rule:MF_03031}, Kiaa4215, mAgo2, mKIAA4215, PAZ Piwi domain protein, Piwi/Argonaute family protein meIF2C2, PPD, Protein argonaute-1, protein argonaute-2, Protein slicer, Q10
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
239528, 27161, 59117
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Dysferlin
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O75923, Q9ESD7
Gene Symbols: DYSF
Immunogen: Synthetic peptide within Human Dysferlin aa 113-162
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: JF05-54
Conjugate: Unconjugated
Gene: DYSF
Gene Alias: 2310004N10Rik, AI604795, D6Pas3, Dysf, Dysferlin, dysferlin variant a, dysferlin_a, dystrophy-associated fer-1-like 1, dystrophy-associated fer-1-like protein, FER1L1, fer-1-like family member 1, fer-1-like protein 1, FLJ00175, FLJ90168, LGMD2B, limb girdle muscular dystrophy 2B (autosomal recessive), MMD1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 26903, 8291
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Dysferlin
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O75923, Q9ESD7
Gene Symbols:
DYSF
Immunogen:
Synthetic peptide within Human Dysferlin aa 113-162
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
JF05-54
Conjugate:
Unconjugated
Gene:
DYSF
Gene Alias:
2310004N10Rik, AI604795, D6Pas3, Dysf, Dysferlin, dysferlin variant a, dysferlin_a, dystrophy-associated fer-1-like 1, dystrophy-associated fer-1-like protein, FER1L1, fer-1-like family member 1, fer-1-like protein 1, FLJ00175, FLJ90168, LGMD2B, limb girdle muscular dystrophy 2B (autosomal recessive), MMD1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
26903, 8291
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CNPase
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P09543, P13233, P16330
Gene Symbols: CNP
Immunogen: Synthetic peptide within Human CNPase aa 386-421
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: JF10-25
Conjugate: Unconjugated
Gene: CNP
Gene Alias: 2', 3' cyclic nucleotide 3' phosphohydrolase, 2',3'-cyclic nucleotide 3' phosphodiesterase, 2',3'-cyclic nucleotide 3' phosphodiesterase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, Cnp1, Cnp-1, CNPase, CNPF, CNPI, CNPII, cyclic nucleotide phosphodiesterase 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1267, 12799, 25275
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CNPase
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P09543, P13233, P16330
Gene Symbols:
CNP
Immunogen:
Synthetic peptide within Human CNPase aa 386-421
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
JF10-25
Conjugate:
Unconjugated
Gene:
CNP
Gene Alias:
2', 3' cyclic nucleotide 3' phosphohydrolase, 2',3'-cyclic nucleotide 3' phosphodiesterase, 2',3'-cyclic nucleotide 3' phosphodiesterase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, Cnp1, Cnp-1, CNPase, CNPF, CNPI, CNPII, cyclic nucleotide phosphodiesterase 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1267, 12799, 25275
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: NQO1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P05982, P15559, Q64669
Gene Symbols: NQO1
Immunogen: Synthetic peptide within Human NQO1 aa 1-49
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot, Western Blot
Clone: JF440-1
Conjugate: Unconjugated
Gene: NQO1
Gene Alias: AV001255, Azoreductase, DHQU, DIA4, Diaphorase (NADH/NADPH), diaphorase (NADH/NADPH) (cytochrome b-5 reductase), Diaphorase 4, diaphorase 4 (NADH/NADPH), diaphorase-4, dioxin-inducible 1, DTD, DT-diaphorase, menadione reductase, NAD(P)H dehydrogenase (quinone), NAD(P)H dehydrogenase [quinone] 1, NAD(P)H dehydrogenase, quinone 1, NAD(P)H menadione oxidoreductase 1, dioxin inducible, NAD(P)H quinone dehydrogenase 1, NAD(P)H: quinone oxidoreductase 1, NAD(P)H:menadione oxidoreductase, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, NADPH-d, nicotinamide adenine dinucleotide phosphate diaphorase, Nmo1, Nmo-1, Nmor1, NMORI, NQ01, NQO1, Ox1, Ox-1, phylloquinone reductase, QR1, quinone reductase 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1728, 18104, 24314
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
NQO1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P05982, P15559, Q64669
Gene Symbols:
NQO1
Immunogen:
Synthetic peptide within Human NQO1 aa 1-49
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot, Western Blot
Clone:
JF440-1
Conjugate:
Unconjugated
Gene:
NQO1
Gene Alias:
AV001255, Azoreductase, DHQU, DIA4, Diaphorase (NADH/NADPH), diaphorase (NADH/NADPH) (cytochrome b-5 reductase), Diaphorase 4, diaphorase 4 (NADH/NADPH), diaphorase-4, dioxin-inducible 1, DTD, DT-diaphorase, menadione reductase, NAD(P)H dehydrogenase (quinone), NAD(P)H dehydrogenase [quinone] 1, NAD(P)H dehydrogenase, quinone 1, NAD(P)H menadione oxidoreductase 1, dioxin inducible, NAD(P)H quinone dehydrogenase 1, NAD(P)H: quinone oxidoreductase 1, NAD(P)H:menadione oxidoreductase, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, NADPH-d, nicotinamide adenine dinucleotide phosphate diaphorase, Nmo1, Nmo-1, Nmor1, NMORI, NQ01, NQO1, Ox1, Ox-1, phylloquinone reductase, QR1, quinone reductase 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1728, 18104, 24314
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid