PIMA532662

PRKAR2B Recombinant Rabbit Monoclonal Antibody (JA11-69), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532662-Each-of-1 In Stock ₹ 44,619.54

PIMA532662 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

PRKAR2B

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P12369, P31323, P31324

Gene Symbols

Prkar2b

Immunogen

Synthetic peptide within Human PKA 2 beta aa 369-418

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

JA11-69

Conjugate

Unconjugated

Gene

Prkar2b

Gene Alias

AI451071, AW061005, cAMP-dependent protein kinase RII-beta regulatory subunit, cAMP-dependent protein kinase type II-beta regulatory chain, cAMP-dependent protein kinase type II-beta regulatory subunit, H_RG363E19.2, Pkarb2, PKARIIbeta, PRKAR2, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, protein kinase, cAMP dependent regulatory, type II beta, protein kinase, cAMP-dependent, regulatory subunit type II beta, protein kinase, cAMP-dependent, regulatory, type II, beta, RATDNA, RII(beta), RII-BETA, Type II beta regulatory subunit of cAMP-dependent protein kinase, WUGSC:H_RG363E19.2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

19088, 24679, 5577

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • cAMP is a signaling molecule important for a variety of cellular functions
  • cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins
  • The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits
  • cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits
  • Four different regulatory subunits and three catalytic subunits have been identified in humans
  • The protein encoded by this gene is one of the regulatory subunits
  • This subunit can be phosphorylated by the activated catalytic subunit
  • This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells
  • Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity
  • The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol.

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Show Difference

Img

Thermo Scientific

PIMA532662

--


Antigen:
PRKAR2B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P12369, P31323, P31324

Gene Symbols:
Prkar2b

Immunogen:
Synthetic peptide within Human PKA 2 beta aa 369-418

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JA11-69

Conjugate:
Unconjugated

Gene:
Prkar2b

Gene Alias:
AI451071, AW061005, cAMP-dependent protein kinase RII-beta regulatory subunit, cAMP-dependent protein kinase type II-beta regulatory chain, cAMP-dependent protein kinase type II-beta regulatory subunit, H_RG363E19.2, Pkarb2, PKARIIbeta, PRKAR2, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, protein kinase, cAMP dependent regulatory, type II beta, protein kinase, cAMP-dependent, regulatory subunit type II beta, protein kinase, cAMP-dependent, regulatory, type II, beta, RATDNA, RII(beta), RII-BETA, Type II beta regulatory subunit of cAMP-dependent protein kinase, WUGSC:H_RG363E19.2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
19088, 24679, 5577

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532665

--


Antigen:
Tyrosinase

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P11344, P14679

Gene Symbols:
TYR

Immunogen:
Recombinant protein within Human Tyrosinase aa 1-340

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JA52-11

Conjugate:
Unconjugated

Gene:
TYR

Gene Alias:
albino, albino locus protein, ATN, C, CMM8, LB24-AB, monophenol monooxygenase, Oca1, OCA1A, OCAIA, oculocutaneous albinism IA, SHEP3, SK29-AB, skc35, Tumor rejection antigen AB, TYR, Tyrosinase, tyrosinase (oculocutaneous albinism IA), tyrosinase precursor

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
22173, 7299

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532670

--


Antigen:
FAP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q12884

Gene Symbols:
FAP

Immunogen:
Recombinant protein within Human FAP1 aa 1-160

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
JA56-11

Conjugate:
Unconjugated

Gene:
FAP

Gene Alias:
170 kDa melanoma membrane-bound gelatinase, Antiplasmin-cleaving enzyme FAP, soluble form, APCE, Dipeptidyl peptidase FAP, DPPIV, Fap, FAPA, FAPalpha, fibroblast activation protein, fibroblast activation protein alpha, fibroblast activation protein, alpha, gelatine degradation protease FAP, Integral membrane serine protease, post-proline cleaving enzyme, Prolyl endopeptidase FAP, seprase, Serine integral membrane protease, SIMP, Surface-expressed protease

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2191

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532672

--


Antigen:
Alpha Sarcoglycan

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P82350, Q16586

Gene Symbols:
SGCA

Immunogen:
Synthetic peptide within Human alpha sarcoglycan aa 338-387

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
JA51-81

Conjugate:
Unconjugated

Gene:
SGCA

Gene Alias:
50 kDa dystrophin-associated glycoprotein, 50DAG, 50kD DAG, adhalin, ADL, Alpha-sarcoglycan, alpha-SG, Asg, DAG2, DMDA2, Dystroglycan 2, Dystroglycan2, dystroglycan-2, LGMD2D, limb girdle muscular dystrophy 2D, sarcoglycan alpha, sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein), sarcoglycan, alpha (dystrophin-associated glycoprotein), SCARMD1, SG alpha, SG-alpha, Sgca

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20391, 303468, 6442

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid