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PIMA532735

CYP2D6 Recombinant Rabbit Monoclonal Antibody (JM44-23), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532735-Each-of-1 In Stock ₹ 45,646.26

PIMA532735 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

CYP2D6

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P10635

Gene Symbols

CYP2D6

Immunogen

Recombinant protein within Human Cytochrome P450 2D6 aa 301-497

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

JM44-23

Conjugate

Unconjugated

Gene

CYP2D6

Gene Alias

AI303445, Cholesterol 25-hydroxylase, CPD6, CYP2D, Cyp2d10, Cyp2d-10, Cyp2d13, Cyp2d18, Cyp2d-18, Cyp2d22, Cyp2d3, Cyp2d-3, Cyp2d4, Cyp2d-4, Cyp2d4v1, Cyp2d4v2, Cyp2d6, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID10, CYPIID18, CYPIID3, CYPIID4, CYPIID6, Cytochrome P450 2D10, cytochrome P450 2d18, Cytochrome P450 2D-29, Cytochrome P450 2D3, cytochrome P450 2D-35, cytochrome P450 2D4, Cytochrome P450 2D6, cytochrome P450 family 2 subfamily D member 6, cytochrome P450, 2d10, cytochrome P450, family 2, subfamily d, polypeptide 10, cytochrome P450, family 2, subfamily d, polypeptide 13, cytochrome P450, family 2, subfamily d, polypeptide 22, cytochrome P450, family 2, subfamily d, polypeptide 3, cytochrome P450, family 2, subfamily d, polypeptide 4, cytochrome P450, family 2, subfamily d, polypeptide 6, cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2, cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2, cytochrome P450, subfamily 2D, polypeptide 6, cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2, cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2, cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6, cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1, cytochrome P450, subfamily IID, polypeptide 6, Cytochrome P450, subfamily IID3, Cytochrome P450, subfamily IID4, cytochrome P450-16-alpha, Cytochrome P450CB, Cytochrome P450-CMF3, cytochrome P450-DB1, Cytochrome P450-DB3, cytochrome P450-DB4, debrisoquine 4-hydroxylase, flavoprotein-linked monooxygenase, microsomal monooxygenase, nonfunctional cytochrome P450 2D6, P450 2D-29/2D-35, P450-2D, P450C2D, P450-CMF3, P450DB1, P450-DB1, P450-DB3, P450-DB4, testosterone 16-alpha hydroxylase, xenobiotic monooxygenase

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1565

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Cytochrome p450 2D6 (CYP2D6) is a member of the cytochrome P450 superfamily of enzymes
  • The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids
  • This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs
  • Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant
  • The gene is highly polymorphic in the population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates
  • The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1
  • Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Img

Thermo Scientific

PIMA532735

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Antigen:
CYP2D6
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P10635
Gene Symbols:
CYP2D6
Immunogen:
Recombinant protein within Human Cytochrome P450 2D6 aa 301-497
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
JM44-23
Conjugate:
Unconjugated
Gene:
CYP2D6
Gene Alias:
AI303445, Cholesterol 25-hydroxylase, CPD6, CYP2D, Cyp2d10, Cyp2d-10, Cyp2d13, Cyp2d18, Cyp2d-18, Cyp2d22, Cyp2d3, Cyp2d-3, Cyp2d4, Cyp2d-4, Cyp2d4v1, Cyp2d4v2, Cyp2d6, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID10, CYPIID18, CYPIID3, CYPIID4, CYPIID6, Cytochrome P450 2D10, cytochrome P450 2d18, Cytochrome P450 2D-29, Cytochrome P450 2D3, cytochrome P450 2D-35, cytochrome P450 2D4, Cytochrome P450 2D6, cytochrome P450 family 2 subfamily D member 6, cytochrome P450, 2d10, cytochrome P450, family 2, subfamily d, polypeptide 10, cytochrome P450, family 2, subfamily d, polypeptide 13, cytochrome P450, family 2, subfamily d, polypeptide 22, cytochrome P450, family 2, subfamily d, polypeptide 3, cytochrome P450, family 2, subfamily d, polypeptide 4, cytochrome P450, family 2, subfamily d, polypeptide 6, cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2, cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2, cytochrome P450, subfamily 2D, polypeptide 6, cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2, cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2, cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6, cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1, cytochrome P450, subfamily IID, polypeptide 6, Cytochrome P450, subfamily IID3, Cytochrome P450, subfamily IID4, cytochrome P450-16-alpha, Cytochrome P450CB, Cytochrome P450-CMF3, cytochrome P450-DB1, Cytochrome P450-DB3, cytochrome P450-DB4, debrisoquine 4-hydroxylase, flavoprotein-linked monooxygenase, microsomal monooxygenase, nonfunctional cytochrome P450 2D6, P450 2D-29/2D-35, P450-2D, P450C2D, P450-CMF3, P450DB1, P450-DB1, P450-DB3, P450-DB4, testosterone 16-alpha hydroxylase, xenobiotic monooxygenase
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1565
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid

Img

Thermo Scientific

PIMA532737

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Antigen:
Protein C
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P04070
Gene Symbols:
PROC
Immunogen:
Recombinant protein within Human Protein C aa 290-380
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
JM93-61
Conjugate:
Unconjugated
Gene:
PROC
Gene Alias:
Activation peptide, Anticoagulant protein C, APC, autoprothrombin IIA, Blood coagulation factor XIV, EDQVDPRLIDGK, inactivator of coagulation factors Va, VIII, PC, prepro-protein C, Proc, PROC1, protein C, protein C (inactivator of coagulation factors Va and VIIIa), protein C prepropeptide, protein C, inactivator of coagulation factors Va and VIIIa, THPH3, THPH4, type I protein C, vitamin K-dependent protein C, Vitamin K-dependent protein C heavy chain, Vitamin K-dependent protein C light chain
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5624
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid

Img

Thermo Scientific

PIMA532740

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Antigen:
Ephrin B2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P52799, P52800
Gene Symbols:
Efnb2
Immunogen:
Synthetic peptide within Human Ephrin B aa 47-96
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot, Western Blot
Clone:
JM53-21
Conjugate:
Unconjugated
Gene:
Efnb2
Gene Alias:
EFNB2, efnb2a, Elf2, ELF-2, EPH-related receptor tyrosine kinase ligand 5, ephrin B2, ephrin B2a, ephrin-B2, Ephrin-B2a, Epl5, EPLG5, HTK ligand, Htkl, HTK-L, id:ibd5072, Lerk5, LERK-5, ligand of eph-related kinase 5, MGC126226, MGC126227, MGC126228, NLERK-1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
13642, 1948, 306636
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid

Img

Thermo Scientific

PIMA532743

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Antigen:
PKC mu
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O94806, Q15139, Q5XIS9, Q62101, Q8BZ03, Q8K1Y2, Q9BZL6, Q9WTQ1
Gene Symbols:
PRKD1, Prkd2, Prkd3
Immunogen:
Synthetic peptide within Human PKC aa 201-250
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
JM30-17
Conjugate:
Unconjugated
Gene:
PRKD1
Gene Alias:
4930557O20Rik, 5730497N19Rik, AI325941, DKFZP586E0820, EPK2, HSPC187, nPKC-D1, nPKC-D2, nPKC-mu, nPKC-nu, PKC mu, PKC nu, PKC u, PKC v, Pkcm, PKCmu, PKC-MU, Pkcnu, PKC-NU, PKCu, PKC-u, PKCv, PKC-v, Pkd, PKD1, PKD2, PKD3, Prkcm, PRKCN, Prkd1, PRKD2, PRKD3, Protein kinase C mu type, protein kinase C nu type, protein kinase C, mu, protein kinase C, nu, protein kinase D, protein kinase D1, protein kinase D2, protein kinase D3, protein kinase EPK2, RGD1308054, Serine/threonine-protein kinase D1, serine/threonine-protein kinase D2, Serine/threonine-protein kinase D3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
101540, 18760, 23683, 25865, 292658, 313834, 5587, 75292, 85421
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid