PIMA532897

Axl Monoclonal Antibody (C4-A8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532897-Each-of-1 In Stock ₹ 51,849.36

PIMA532897 - Each of 1

₹ 51,849.36

In Stock

Quantity

1

Base Price: ₹ 51,849.36

GST (18%): ₹ 9,332.885

Total Price: ₹ 61,182.245

Antigen

Axl

Classification

Monoclonal

Concentration

2 mg/mL

Formulation

PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P30530

Gene Symbols

AXL

Immunogen

Recombinant protein with Human UFO aa 10-160

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Western Blot, Western Blot

Clone

C4-A8

Conjugate

Unconjugated

Gene

AXL

Gene Alias

Adhesion-related kinase, AI323647, ARK, AXL, AXL oncogene, AXL receptor tyrosine kinase, AXL transforming sequence/gene, AZF1, JTK11, oncogene AXL, sAXL, soluble AXL, Tyro7, Tyrosine-protein kinase receptor UFO, Ufo, ufo oncogene homolog

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

558

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Mouse Monoclonal Antibody AXL is a chronic myelogenous leukemia-associated oncogene that is also associated with colon cancer and melanoma
  • The AXL protein is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6, and is involved in the stimulation of cell proliferation
  • TAM receptors are also involved in phagocytosis of apoptotic cells
  • Mice lacking all three TAM receptors have several degenerative phenotypes linked to inefficient removal of apoptotic cells and membranes (e.g., in the retina and the male reproductive tract) and develop a severe autoimmune phenotype akin to systemic lupus erythematosus, including the production of broad spectrum auto-antibodies
  • In addition, Axl may function as a putative entry receptor for filoviruses
  • Axl is also used to identify a specific subpopulation of human blood dendritic cells, also referred to as Siglec 6+/Axl+ dendritic cells
  • Cellular expression of Axl can be upregulated by TLR ligands, such as LPS or poly I:C
  • Soluble Axl is generated by proteolytic cleavage of the membrane form
  • Increased plasma levels may be indicative of inflammation and cancer.

Compare Similar Items

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Img

Thermo Scientific

PIMA532897

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Antigen:
Axl

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P30530

Gene Symbols:
AXL

Immunogen:
Recombinant protein with Human UFO aa 10-160

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Western Blot, Western Blot

Clone:
C4-A8

Conjugate:
Unconjugated

Gene:
AXL

Gene Alias:
Adhesion-related kinase, AI323647, ARK, AXL, AXL oncogene, AXL receptor tyrosine kinase, AXL transforming sequence/gene, AZF1, JTK11, oncogene AXL, sAXL, soluble AXL, Tyro7, Tyrosine-protein kinase receptor UFO, Ufo, ufo oncogene homolog

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
558

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532900

--


Antigen:
DPY30

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q99LT0, Q9C005

Gene Symbols:
DPY30

Immunogen:
Recombinant protein within mouse DPY30 aa 1-99

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
1-6

Conjugate:
Unconjugated

Gene:
DPY30

Gene Alias:
2810410M20Rik, Aip1, C87842, Cps25, dosage compensation-related protein DPY30, DPY30, dpy-30 histone methyltransferase complex regulatory subunit, dpy-30 homolog, dpy-30 homolog (C. elegans), dpy-30, histone methyltransferase complex regulatory subunit, Dpy-30L, dpy-30-like protein, HDPY-30, Protein dpy-30 homolog, protein rAIP1, Saf19, Unknown (protein for MGC:136993)

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
66310, 84661

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532901

--


Antigen:
LIN28B

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q6ZN17

Gene Symbols:
LIN28B

Immunogen:
Recombinant protein within Human Lin28B aa 73-250

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Western Blot, Western Blot

Clone:
A2-4-5

Conjugate:
Unconjugated

Gene:
LIN28B

Gene Alias:
2810403D23Rik, CSDD2, D030047M17Rik, lin-28 homolog B, lin-28 homolog B (C. elegans), Lin-28.2, Lin28b, Lin-28B, Protein lin-28 homolog B

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
389421

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532903

--


Antigen:
CDK2

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P24941, P97377, Q63699

Gene Symbols:
CDK2

Immunogen:
Synthetic peptide within Human CDK2 aa 249-298

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Western Blot, Western Blot

Clone:
10-D7

Conjugate:
Unconjugated

Gene:
CDK2

Gene Alias:
A630093N05Rik, CDC28, CDC2A, cdc2-related protein kinase, CDK1, CDK2, CDKN2, Cell division protein kinase 2, cyclin dependent kinase 2, cyclin dependent kinase 2-alpha, cyclin-dependent kinase 2, EC 2.7.11.22, EC 2.7.11.23, kinase Cdc2, MPF, p33 protein kinase, p33(CDK2), p33CDK2, p34 protein kinase

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1017, 12566, 362817

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid