PIMA532963

IL18BP Monoclonal Antibody (7C6), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA532963-Each-of-1 In Stock ₹ 48,640.86

PIMA532963 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

IL18BP

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

O95998

Gene Symbols

IL18BP

Immunogen

Recombinant full length Human IL18BP.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Western Blot

Clone

7C6

Conjugate

Unconjugated

Gene

IL18BP

Gene Alias

Igifbp, Il18bp, IL-18BP, IL18BPa, interferon gamma inducing factor binding protein, interferon gamma-inducing factor-binding protein, interleukin 18 binding protein, interleukin-18 binding protein, interleukin-18-binding protein, MC51L-53L-54L homolog gene product, MC54L, Tadekinig-alfa

Host Species

Mouse

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10068

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Interleukin-18 binding protein (IL-18BP) is a constitutively secreted glycoprotein that acts as a natural antagonist for interleukin-18 (IL-18) by preventing interaction between IL-18 and its receptors
  • Through this binding, IL-18BP neutralizes the proinflammatory role of IL-18 in cell-mediated immune responses, resulting in reduced IFN-gamma production by T helper type I cells and inhibition of allospecific cytotoxic T lymphocyte (CTL) activity through augmented natural killer (NK) cell cytotoxicity
  • As an inhibitor of IL-18 and an essential component of skin homeostasis, IL-18BP has been linked to a variety of diseases, including eczema, asthma, and the autoimmune condition, Crohn's disease
  • The upregulation of IL-18BP by keratinocytes expressing the human papillomavirus (HPV) E7 oncoprotein has been shown to decrease IL-18-induced IFN-gamma production and IL-18-mediated T cell activation
  • Elevated levels of IL-18 and IL-18BP, as well as proinflammatory cytokines IFN-gamma, TNF-alpha, IL-1beta and IL-8, have been linked to chronic inflammation and observed in macrophages (including Kupffer cells) isolated from lesions and intestinal tissues of Crohn's disease patients
  • As a member of the immunoglobulin-like class of receptors, IL-18BP contains a single immunoglobulin (Ig) domain; although two (b and d) of the four identified human isoforms (a-d) contain incomplete domains that greatly reduce their binding affinity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532963

--


Antigen:
IL18BP

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O95998

Gene Symbols:
IL18BP

Immunogen:
Recombinant full length Human IL18BP.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
7C6

Conjugate:
Unconjugated

Gene:
IL18BP

Gene Alias:
Igifbp, Il18bp, IL-18BP, IL18BPa, interferon gamma inducing factor binding protein, interferon gamma-inducing factor-binding protein, interleukin 18 binding protein, interleukin-18 binding protein, interleukin-18-binding protein, MC51L-53L-54L homolog gene product, MC54L, Tadekinig-alfa

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10068

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532965

--


Antigen:
SMYD2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q8R5A0, Q9NRG4

Gene Symbols:
SMYD2

Immunogen:
Recombinant full length Human SMYD2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
8E5

Conjugate:
Unconjugated

Gene:
SMYD2

Gene Alias:
1110020E07Rik, 4930402C15, Histone methyltransferase SMYD2, HSKM-B, KMT3C, lysine N-methyltransferase 3C, N-lysine methyltransferase SMYD2, SET and MYND domain containing 2, SET and MYND domain-containing protein 2, Smyd2, zinc finger, MYND domain containing 14, ZMYND14

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
226830, 56950

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532967

--


Antigen:
MSI1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
O43347, Q61474, Q8K3P4

Gene Symbols:
MSI1

Immunogen:
Recombinant full length Human Musashi-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Western Blot

Clone:
8G2

Conjugate:
Unconjugated

Gene:
MSI1

Gene Alias:
fb40b12, hypothetical protein LOC541389, m-Msi-1, ms1, msi1, msi1b, Msi1h, Musahi1, musashi homolog 1, Musashi homolog 1(Drosophila), musashi RNA binding protein 1, musashi RNA binding protein 1b, musashi RNA-binding protein 1, musashi1, musashi-1, RNA-binding protein Musashi homolog 1, RNA-binding protein Musashi homolog 1 L+35bp, RNA-binding protein Musashi homolog 1 Long, RNA-binding protein Musashi homolog 1b, wu:fb40b12, zgc:103751, zMsi1

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17690, 259272, 4440

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532972

--


Antigen:
FEN1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P39748, P39749, Q5XIP6

Gene Symbols:
FEN1

Immunogen:
Purified recombinant human FEN-1 protein fragments expressed in E.coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot, Western Blot

Clone:
7H8

Conjugate:
Unconjugated

Gene:
FEN1

Gene Alias:
AW538437, DNase IV, fen1, FEN-1, fen1 {ECO:0000255, FEN-1 {ECO:0000255, Flap endonuclease 1, flap endonuclease 1 {ECO:0000255, flap structure specific endonuclease 1, flap structure-specific endonuclease 1, flap structure-specific endonuclease 1 {ECO:0000255, HAMAP-Rule:MF_03140}, hFEN-1, Maturation factor 1, maturation factor-1, MF1, RAD2

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14156, 2237, 84490

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid