PIMA533183

Phospho-c-Myc (Ser62) Recombinant Rabbit Monoclonal Antibody (2A10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533183-Each-of-1 In Stock ₹ 48,640.86

PIMA533183 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

Phospho-c-Myc (Ser62)

Classification

Recombinant Monoclonal

Concentration

1.4 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P01106

Gene Symbols

MYC

Immunogen

A synthesized peptide derived from human Phospho-MYC (S62)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

2A10

Conjugate

Unconjugated

Gene

MYC

Gene Alias

AU016757, Avian myelocytomatosis viral (v-myc) oncogene homolog, avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, class E basic helix-loop-helix protein 39, cmyc, c-Myc, c-myc epitope tag, c-myc proto-oncogene, mMyc, MRTL, Myc, Myc protein, Myc proto-oncogene protein, MYC proto-oncogene, bHLH transcription factor, Myc2, MYCC, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene-like protein

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

4609

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • The c-Myc protein is a 62 kDa transcription factor that is encoded by the c-Myc gene on human chromosome 8q24
  • c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression
  • The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation
  • Studies have shown that c-Myc is essential for vasculogenesis and angiogenesis in tumor development, which distributes blood throughout the cells
  • The c-myc oncogene (p62 c-myc) is involved in the control of normal cellular proliferation and differentiation, and the deregulated expression of c-Myc induces apoptosis in different cell types
  • Antibodies against c-myc epitopes recognize overexpressed proteins containing Myc epitope tag fused to either amino- or carboxy-termini of targeted proteins
  • c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease
  • Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas
  • Translocation of the c-myc locus on chromosome 8 to the immunoglobulin loci on chromosome 14 (heavy chain); 2 (delta light chain); or 22 (light chain) is described in Burkitts lymphoma and other B-cell lymphoproliferative conditions
  • An aberrant expression of the c-myc gene occurs in tumors of different origins such as colorectal, gastric, gallbladder, hepatic, mammary, ovarian, endometrial, head and neck, pulmonary, prostatic, thyroidal, oral, ocular, nasopharyngeal, endocrine, as well as hematopoietic neoplasms.

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Thermo Scientific

PIMA533183

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Antigen:
Phospho-c-Myc (Ser62)

Classification:
Recombinant Monoclonal

Concentration:
1.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P01106

Gene Symbols:
MYC

Immunogen:
A synthesized peptide derived from human Phospho-MYC (S62)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
2A10

Conjugate:
Unconjugated

Gene:
MYC

Gene Alias:
AU016757, Avian myelocytomatosis viral (v-myc) oncogene homolog, avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, class E basic helix-loop-helix protein 39, cmyc, c-Myc, c-myc epitope tag, c-myc proto-oncogene, mMyc, MRTL, Myc, Myc protein, Myc proto-oncogene protein, MYC proto-oncogene, bHLH transcription factor, Myc2, MYCC, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene-like protein

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4609

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA533185

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Antigen:
Phospho-PAK1/2/3 (Ser139, Ser141, Ser144)

Classification:
Recombinant Monoclonal

Concentration:
0.85 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
O75914, Q13153, Q13177

Gene Symbols:
Pak1, PAK2, PAK3

Immunogen:
A synthesized peptide derived from human Phospho-PAK1/PAK2/PAK3 (S144+S141+S139)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
3H12

Conjugate:
Unconjugated

Gene:
PAK3

Gene Alias:
5330420P17Rik, A130002K10Rik, activated protein kinase alpha, ADRB2, adriamycin resistance-associated, AI836325, Alpha-PAK, ARA, AW045634, Beta-PAK, bPAK, CDC42/RAC effector kinase PAK-A, CDC42/RAC effector kinase PAK-B, CDKN1A, C-t-PAK2, D16Ertd269e, EC 2.7.11.1, gamma pak, gamma-PAK, hPAK3, kinase PAK1, mKIAA4182, MRX30, MRX47, oligophrenin-3, OPHN3, p21 (CDKN1A)-activated kinase 1, p21 (CDKN1A)-activated kinase 2, p21 (CDKN1A)-activated kinase 3, p21 (RAC1) activated kinase 1, p21 (RAC1) activated kinase 2, p21 (RAC1) activated kinase 3, p21 protein (Cdc42/Rac)-activated kinase 1, p21 protein (Cdc42/Rac)-activated kinase 2, p21 protein (Cdc42/Rac)-activated kinase 3, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast), p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related), p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related), p21-activated kinase 1, p21-activated kinase 2, p21-activated kinase 3, p27, p34, p58, p65-PAK, p68-PAK, PAK 1, PAK alpha, PAK beta, PAK gamma, Pak1, PAK-1, Pak2, PAK-2, PAK-2p27, PAK-2p34, PAK3, PAK-3, PAK3beta, PAK65, Pak65alpha, Pak65beta, Paka, PAKalpha, Pakb, PAKgamma, Protein kinase MUK2, S6/H4 kinase, Serine/threonine-protein kinase PAK 1, serine/threonine-protein kinase PAK 2, Serine/threonine-protein kinase PAK 3, STE20 homolog, yeast, Stk4

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5058, 5062, 5063

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA533187

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Antigen:
Phospho-RNA pol II CTD (Ser2)

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P24928

Gene Symbols:
POLR2A

Immunogen:
A synthesized peptide derived from human Phospho-POLR2A (S2)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
2G1

Conjugate:
Unconjugated

Gene:
POLR2A

Gene Alias:
220kDa, AW321876, DNA polymerase alpha 1 catalytic subunit, DNA polymerase alpha 1, 180 kDa, DNA polymerase alpha 1, catalytic subunit, DNA polymerase alpha catalytic subunit, DNA polymerase alpha catalytic subunit p180, DNA polymerase alpha p180 subunit, DNA polymerase alpha subunit I, DNA polymerase epsilon catalytic subunit, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, DUN2, EC 2.7.7.6, G7a/Bat6Hom, hRPB220, hsRPB1, I79_002751, I79_016081, MGC75453, N0825, NSX, p180, Pol II S2p, POL2, Pola, Pola1, POLR2, POLR2A, POLRA, polymerase (DNA directed), alpha 1, polymerase (DNA directed), alpha 1, catalytic subunit, polymerase (DNA) alpha 1, catalytic subunit, polymerase (DNA-directed), alpha (70kD), Polymerase (RNA II (DNA directed), large polypeptide, polymerase (RNA) II (DNA directed) polypeptide A, polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, polymerase (RNA) II subunit A, POLYMERASE II, polymerase, alpha 1, RNA, RNA POL2, RNA polymerase II 1, RNA polymerase II carboxy-terminal domain, RNA polymerase II C-terminal domain, RNA polymerase II largest subunit, RNA polymerase II subunit A, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RP02, Rpb1, RPB220, RPBh1, Rpii215, RpIILS, RPO2, RPO21, Rpo2-1, RPOL2, SUA8, YNL262W

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5430

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA533190

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Antigen:
PRKAR1A

Classification:
Recombinant Monoclonal

Concentration:
0.55 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P10644

Gene Symbols:
PRKAR1A

Immunogen:
A synthesized peptide derived from human PRKAR1A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
1C3

Conjugate:
Unconjugated

Gene:
PRKAR1A

Gene Alias:
1300018C22Rik, ACRDYS1, ADOHR, cAMP-dependent protein kinase regulatory subunit RIalpha, cAMP-dependent protein kinase type I-alpha regulatory chain, cAMP-dependent protein kinase type I-alpha regulatory subunit, cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed, CAR, Carney complex type 1, CNC, CNC1, PKR1, PPNAD1, PRKAR1, Prkar1a, protein kinase A type 1a regulatory subunit, protein kinase cAMP-dependent type I regulatory subunit alpha, protein kinase, cAMP dependent regulatory, type 1, alpha, protein kinase, cAMP dependent regulatory, type I, alpha, protein kinase, cAMP-dependent, regulatory subunit type I alpha, protein kinase, cAMP-dependent, regulatory, type I, alpha, RIalpha, RIIA, Tissue-specific extinguisher 1, Tse1, Tse-1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5573

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid