PIMA533357
CFHR1/CFHR2 Monoclonal Antibody (JHD-7.10.1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533357-Each-of-1 | In Stock | ₹ 78,287.40 |
PIMA533357 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 78,287.40
GST (18%): ₹ 14,091.732
Total Price: ₹ 92,379.132
Antigen
CFHR1/CFHR2
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.
P36980, Q03591
Gene Symbols
CFHR1, CFHR2
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
3078, 3080
Content And Storage
4° C
Form
Liquid
Applications
ELISA
Clone
JHD-7.10.1
Conjugate
Unconjugated
Gene
CFHR2
Gene Alias
CFHL; CFHL1; CFHL1P; CFHL2; CFHR1; CFHR1P; CFHR2; complement factor H related 1; complement factor H related 2; complement factor H-related 1 pseudogene; complement factor H-related 2; complement factor H-related protein 1; Complement factor H-related protein 2; DDESK59; factor H-related gene 2; FHR1; FHR-1; FHR2; FHR-2; H factor (complement)-like 1; H factor (complement)-like 2; H factor (complement)-like 3; h factor-like 3; H factor-like protein 1; h factor-like protein 2; H36; H36-1; H36-2; H-factor-like 1; HFL1; HFL2; HFL3
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Product is supplied at 1 mL (100 μL/mL)
- Due to a high degree of amino acid sequence homology this product is cross-reactive with both CFHR1 and 2
- In humans the complement factor H protein family consists of complement factor H, the factor H-like protein 1 and five factor H-related proteins termed 1 to 5
- All members of this group are expressed primarily in the liver and subsequently secreted into plasma
- The secreted forms of these proteins are composed exclusively of repetitive protein domains termed short consensus repeats (SCR)
- The CFHR1 protein is composed of five SCR domains and circulates in plasma as two differentially glycosylated isoforms (37 kDa and 43 kDa)
- CFHR-2 is composed of four SCRs and is present in human plasma in a non-glycosylated form (24 kDa) and a glycosylated form of 29 kDa
- So far the biological functions of both CFHR-1 and CFHR-2 proteins are poorly understood, however recent studies have shown that CFHR1 is a complement regulator that blocks C5 convertase activity as well as assembly and membrane insertion of the terminal components
- Moreover, genetic variations in the CFHR1 gene are associated with several diseases such as atypical hemolytic uremic syndrome and age-related macular degeneration.
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Antigen: CFHR1/CFHR2
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P36980, Q03591
Gene Symbols: CFHR1, CFHR2
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 3078, 3080
Content And Storage: 4° C
Form: Liquid
Applications: ELISA
Clone: JHD-7.10.1
Conjugate: Unconjugated
Gene: CFHR2
Gene Alias: CFHL; CFHL1; CFHL1P; CFHL2; CFHR1; CFHR1P; CFHR2; complement factor H related 1; complement factor H related 2; complement factor H-related 1 pseudogene; complement factor H-related 2; complement factor H-related protein 1; Complement factor H-related protein 2; DDESK59; factor H-related gene 2; FHR1; FHR-1; FHR2; FHR-2; H factor (complement)-like 1; H factor (complement)-like 2; H factor (complement)-like 3; h factor-like 3; H factor-like protein 1; h factor-like protein 2; H36; H36-1; H36-2; H-factor-like 1; HFL1; HFL2; HFL3
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
CFHR1/CFHR2
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P36980, Q03591
Gene Symbols:
CFHR1, CFHR2
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
3078, 3080
Content And Storage:
4° C
Form:
Liquid
Applications:
ELISA
Clone:
JHD-7.10.1
Conjugate:
Unconjugated
Gene:
CFHR2
Gene Alias:
CFHL; CFHL1; CFHL1P; CFHL2; CFHR1; CFHR1P; CFHR2; complement factor H related 1; complement factor H related 2; complement factor H-related 1 pseudogene; complement factor H-related 2; complement factor H-related protein 1; Complement factor H-related protein 2; DDESK59; factor H-related gene 2; FHR1; FHR-1; FHR2; FHR-2; H factor (complement)-like 1; H factor (complement)-like 2; H factor (complement)-like 3; h factor-like 3; H factor-like protein 1; h factor-like protein 2; H36; H36-1; H36-2; H-factor-like 1; HFL1; HFL2; HFL3
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: Complement Factor B
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P00751
Gene Symbols: CFB
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 629
Content And Storage: 4° C
Form: Liquid
Applications: ELISA, Immunoprecipitation, Western Blot
Clone: P21/15
Conjugate: Unconjugated
Gene: CFB
Gene Alias: AHUS4; AI195813; AI255840; alternative-complement pathway C3/C5 convertase; ARMD14; B; BF; B-factor, properdin; BFD; C2; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFB; CFBD; complement component 2 (within H-2S); complement factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; Da1-24; DADB-122G4.5; Factor B; Fb; FBI12; GBG; glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; H2-Bf; histocompatibility 2, complement component factor B; PBF2; properdin; properdin factor B
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
Complement Factor B
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P00751
Gene Symbols:
CFB
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
629
Content And Storage:
4° C
Form:
Liquid
Applications:
ELISA, Immunoprecipitation, Western Blot
Clone:
P21/15
Conjugate:
Unconjugated
Gene:
CFB
Gene Alias:
AHUS4; AI195813; AI255840; alternative-complement pathway C3/C5 convertase; ARMD14; B; BF; B-factor, properdin; BFD; C2; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFB; CFBD; complement component 2 (within H-2S); complement factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; Da1-24; DADB-122G4.5; Factor B; Fb; FBI12; GBG; glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; H2-Bf; histocompatibility 2, complement component factor B; PBF2; properdin; properdin factor B
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: Complement Factor B
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P00751
Gene Symbols: CFB
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 629
Content And Storage: 4° C
Form: Liquid
Applications: ELISA, Immunoprecipitation, Western Blot
Clone: M13/12
Conjugate: Unconjugated
Gene: CFB
Gene Alias: AHUS4; AI195813; AI255840; alternative-complement pathway C3/C5 convertase; ARMD14; B; BF; B-factor, properdin; BFD; C2; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFB; CFBD; complement component 2 (within H-2S); complement factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; Da1-24; DADB-122G4.5; Factor B; Fb; FBI12; GBG; glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; H2-Bf; histocompatibility 2, complement component factor B; PBF2; properdin; properdin factor B
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
Complement Factor B
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P00751
Gene Symbols:
CFB
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
629
Content And Storage:
4° C
Form:
Liquid
Applications:
ELISA, Immunoprecipitation, Western Blot
Clone:
M13/12
Conjugate:
Unconjugated
Gene:
CFB
Gene Alias:
AHUS4; AI195813; AI255840; alternative-complement pathway C3/C5 convertase; ARMD14; B; BF; B-factor, properdin; BFD; C2; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; CFB; CFBD; complement component 2 (within H-2S); complement factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; Da1-24; DADB-122G4.5; Factor B; Fb; FBI12; GBG; glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; H2-Bf; histocompatibility 2, complement component factor B; PBF2; properdin; properdin factor B
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: MASP1
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P48740
Gene Symbols: MASP1
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 5648
Content And Storage: 4° C
Form: Liquid
Applications: ELISA, Immunoprecipitation, Western Blot
Clone: IE2
Conjugate: Unconjugated
Gene: MASP1
Gene Alias: 3MC1; AW048060; C4/C2 activating component of Ra-reactive factor; CCPII; Complement factor MASP-3; complement-activating component of Ra-reactive factor; Crarf; CRARF1; mannan binding lectin serine peptidase 1; mannan-binding; mannan-binding lectin serine peptidase 1; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor); mannan-binding lectin serine protease 1; Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain; Mannose-binding lectin-associated serine protease 1; mannose-binding protein associated serine protease-1; mannose-binding protein-associated serine protease; MAP1; MAp44; MASP; MASP1; MASP-1; Masp1/3; MASP3; PRSS5; Ra-reactive factor serine protease p100; raRF; Serine protease 5; serine protease MASP1
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
MASP1
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P48740
Gene Symbols:
MASP1
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
5648
Content And Storage:
4° C
Form:
Liquid
Applications:
ELISA, Immunoprecipitation, Western Blot
Clone:
IE2
Conjugate:
Unconjugated
Gene:
MASP1
Gene Alias:
3MC1; AW048060; C4/C2 activating component of Ra-reactive factor; CCPII; Complement factor MASP-3; complement-activating component of Ra-reactive factor; Crarf; CRARF1; mannan binding lectin serine peptidase 1; mannan-binding; mannan-binding lectin serine peptidase 1; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor); mannan-binding lectin serine protease 1; Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain; Mannose-binding lectin-associated serine protease 1; mannose-binding protein associated serine protease-1; mannose-binding protein-associated serine protease; MAP1; MAp44; MASP; MASP1; MASP-1; Masp1/3; MASP3; PRSS5; Ra-reactive factor serine protease p100; raRF; Serine protease 5; serine protease MASP1
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1