PIMA533371

Shiga toxin 2A Monoclonal Antibody (11E10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533371-Each-of-1 In Stock ₹ 83,292.66

PIMA533371 - Each of 1

₹ 83,292.66

In Stock

Quantity

1

Base Price: ₹ 83,292.66

GST (18%): ₹ 14,992.679

Total Price: ₹ 98,285.339

Antigen

Shiga toxin 2A

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 0.1% BSA and no preservative

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Content And Storage

4° C

Form

Liquid

Target Molecule

Chemical

Applications

ELISA, Functional Assay, Western Blot

Clone

11E10

Conjugate

Unconjugated

Gene Alias

Shiga toxin; Shigatoxin Type 2; Shigatoxin Type II; STX2; STX-2a; STX-IIa

Purification Method

Protein G

Regulatory Status

RUO

Target Species

Chemical

Product Type

Antibody

Isotype

IgG1

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Description

  • Product is supplied at 1 mL (100 μL/mL)
  • Application Notes: Functional assay - For inhibition of biological activity in vitro dilutions have to be made according to the amounts of toxin to be inactivated
  • ELISA - antibody can be used as detector
  • Shiga-like toxins (SLTs), are also called Verotoxins
  • Enterohemorrhagic Escherichia coli (EHEC) strains which are primarily of serotypes 0157:H7, 026:H11, and O111:H8 have been incriminated as etiologic agents of hemorrhagic colitis and Hemolytic-uremic syndrome, a generalized disease characterized by acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia
  • There are several distinct E.coli SLTs
  • SLT-I and SLT-II are produced by EHEC
  • SLT-I and Shiga toxin share 99% deduced amino acid sequence homology, whereas SLT-I and SLT-II share about 60% deduced amino acid sequence homology
  • SLT-I and SLT-II are antigenically distinct
  • Antibodies to SLT-II can also neutralize a variant of SLT-II (designated SLT-Iiv) produced by strains of E.coli that cause edema
  • SLT-IIv is cytotoxic for Vero but not HeLa cells, distinguishing it from SLT-II
  • The protein structure of the toxin consists of two domains: the A polypeptide that inhibits protein synthesis by targeting ribosomes, and the B polypeptide pentamer that binds to the eukaryotic cell receptor globotriaosylceramide (Gb3) leading to receptor-mediated endocytosis.

Compare Similar Items

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Thermo Scientific

PIMA533371

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Antigen:
Shiga toxin 2A

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and no preservative

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
4° C

Form:
Liquid

Target Molecule:
Chemical

Applications:
ELISA, Functional Assay, Western Blot

Clone:
11E10

Conjugate:
Unconjugated

Gene Alias:
Shiga toxin; Shigatoxin Type 2; Shigatoxin Type II; STX2; STX-2a; STX-IIa

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA533378

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Antigen:
Nectin 3

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and no preservative

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
4° C

Form:
Liquid

Target Molecule:
__

Applications:
ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Clone:
103-A1

Conjugate:
Unconjugated

Gene Alias:
2610301B19Rik; 3000002N23Rik; 4921513D19Rik; AA407785; AU016832; AW538082; CD113; CDW113; DKFZP566B0846; FLJ90624; nectin 3; nectin cell adhesion molecule 3; Nectin3; Nectin-3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; PPR3; PRR3; PVRL3; PVRR3

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a

Img

Thermo Scientific

PIMA533379

--


Antigen:
CD155

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and no preservative

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
4° C

Form:
Liquid

Target Molecule:
__

Applications:
Flow Cytometry, Functional Assay

Clone:
3F1

Conjugate:
Unconjugated

Gene Alias:
3830421F03Rik; AI325026; AI987993; CD112; CD155; D7Ertd458e; FLJ25946; herpes virus entry mediator B; Herpesvirus entry mediator B; hveB; HVED; mE4; mHveB; Mph; murine herpes virus entry protein B; murine herpesvirus entry protein B; NECL5; necl-5; Nectin cell adhesion molecule 2; Nectin2; Nectin-2; nectin-like 5; nectin-like protein 5; Poliovirus receptor; poliovirus receptor homolog; poliovirus receptor-related 2; poliovirus receptor-related protein 2; poliovirus sensitivity; PVR; Pvrl2; PVS; sCD112; soluble CD112; Taa1; TAGE4; tumor-associated antigen 1; tumor-associated glycoprotein pE4

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a

Img

Thermo Scientific

PIMA533380

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Antigen:
SR-BI

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and no preservative

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
4° C

Form:
Liquid

Target Molecule:
__

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)

Clone:
3D12

Conjugate:
Unconjugated

Gene Alias:
AI120173; CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1); CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen (collagen type I receptor, thrombospondin receptor-like 1); CD36 antigen-like 1; Cd36l1; CD36-related class B scavenger receptor haSR-BI; CLA1; Cla-1; Collagen type I receptor, thrombospondin receptor-like 1; D5Ertd460e; haSR-bI; HDL QTL 1; Hdlq1; HDLQTL6; high density lipoprotein receptor; Hlb398; mSR-BI; Scarb1; scavanger receptor class B type 1; scavenger receptor b1; scavenger receptor class B member 1; scavenger receptor class B type I; scavenger receptor class B type II; scavenger receptor class B type III; scavenger receptor class B, member 1; scavenger receptor class B1; SRB1; SR-B1; SRBI; SR-BI; SR-BII

Purification Method:
Protein G

Regulatory Status:
RUO

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG1