PIMA534746

IRAK2 Recombinant Rabbit Monoclonal Antibody (JG36-23), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA534746-Each-of-1 In Stock ₹ 45,646.26

PIMA534746 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

IRAK2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

O43187

Gene Symbols

IRAK2

Immunogen

Recombinant protein within Human IRAK2 aa 30-270

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

JG36-23

Conjugate

Unconjugated

Gene

IRAK2

Gene Alias

6330415L08Rik; AI649099; interleukin 1 receptor associated kinase 2; interleukin-1 receptor associated kinase-2; interleukin-1 receptor-associated kinase 2; interleukin-1 receptor-associated kinase 2c; interleukin-1 receptor-associated kinase-like 2; Irak2; IRAK-2; MGC150550; mu-IRAK-2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3656

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form

Liquid

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Description

  • Positive Control: PC-3M, A549, HepG2, Jurkat, human tonsil tissue, human prostate cancer tissue, human heart tissue
  • IRAK2 (interleukin-1 receptor-associated kinase-like 2) binds to the IL-1 type I receptor following IL-1 engagment and triggers intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization
  • The pro-inflammatory cytokine IL-1 induces cellular response through two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP)
  • IL-1 receptor-associated kinase (IRAK) mediates activation of NF-kappa-B, which is a pivotal transcription factor mediating inflammatory and immune response
  • A novel member in the IRAK/Pelle family was recently identified and designated IRAK2
  • Both IRAK and IRAK2 recruit to the subunits of the IL-1R complex after IL-1 binding and lead to NF-kappa-B activation
  • IRAKs also associate with Toll-like receptor (TLR) and the dominant negative mutants of IRAKs inhibit LPS-induced NF-kappa-B activation
  • Members in IRAK/Pelle family play a central role in IL-1R and TLR mediated inflammatory responses to cytokine IL-1 and LPS
  • IRAK2 is expressed in a variety of human tissues.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA534746

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Antigen:
IRAK2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O43187

Gene Symbols:
IRAK2

Immunogen:
Recombinant protein within Human IRAK2 aa 30-270

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
JG36-23

Conjugate:
Unconjugated

Gene:
IRAK2

Gene Alias:
6330415L08Rik; AI649099; interleukin 1 receptor associated kinase 2; interleukin-1 receptor associated kinase-2; interleukin-1 receptor-associated kinase 2; interleukin-1 receptor-associated kinase 2c; interleukin-1 receptor-associated kinase-like 2; Irak2; IRAK-2; MGC150550; mu-IRAK-2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3656

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form:
Liquid

Img

Thermo Scientific

PIMA534747

--


Antigen:
VAMP3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q15836

Gene Symbols:
VAMP3

Immunogen:
Recombinant protein within Human Cellubrevin aa 1-100

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
JG36-31

Conjugate:
Unconjugated

Gene:
VAMP3

Gene Alias:
CEB; Cellubrevin; D130027G05Rik; hypothetical protein LOC415163; Syb3; Synaptobrevin-3; vamp; Vamp3; VAMP-3; vesicle associated membrane protein 3; vesicle-associated membrane protein 3; vesicle-associated membrane protein 3 (cellubrevin); zgc:86726

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9341

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form:
Liquid

Img

Thermo Scientific

PIMA534748

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Antigen:
BAZ1B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9UIG0

Gene Symbols:
BAZ1B

Immunogen:
Recombinant protein within Human WSTF aa 2-96

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
JG36-32

Conjugate:
Unconjugated

Gene:
BAZ1B

Gene Alias:
BAZ1B; bromodomain adjacent to zinc finger domain 1B; bromodomain adjacent to zinc finger domain protein 1B; bromodomain adjacent to zinc finger domain, 1B; bromodomain adjacent to zinc finger domain, 1B; Williams-Beuren syndrome chromosome region 9 homolog; C87820; hWALp2; transcription factor WSTF; tyrosine-protein kinase BAZ1B; tyrosine-protein kinase BAZ1B; LOW QUALITY PROTEIN: tyrosine-protein kinase BAZ1B; Tyrosine-protein kinase BAZ1B-like protein; WBSC10; WBSCR10; WBSCR9; williams syndrome transcription factor; Williams syndrome transcription factor homolog; williams-Beuren syndrome chromosomal region 10 protein; Williams-Beuren syndrome chromosomal region 9 protein; williams-Beuren syndrome chromosomal region 9 protein homolog; Williams-Beuren syndrome chromosome region 9 homolog; Wstf

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9031

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form:
Liquid

Img

Thermo Scientific

PIMA534750

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Antigen:
GEF-H1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q92974

Gene Symbols:
ARHGEF2

Immunogen:
Synthetic peptide within Human GEF H1 aa 937-986

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
JG36-46

Conjugate:
Unconjugated

Gene:
ARHGEF2

Gene Alias:
AA408978; ARHGEF2; CG10188; CG10188-PA; CG10188-PB; CG10188-PC; cyst; cyst-PA; cyst-PB; cyst-PC; cysts; DKFZp547L106; DKFZp547P1516; Dmel\CG10188; Dmel_CG10188; FLJ45440; GEF; GEFH1; GEF-H1; Guanine nucleotide exchange factor H1; Kiaa0651; Lbcl1; LBC'S first cousin; Lfc; LFP40; Lymphoid blast crisis-like 1; microtubule-regulated Rho-GEF; mKIAA0651; oncogene LFC; OTTHUMP00000018855; P40; Proliferating cell nucleolar antigen p40; rho guanine nucleotide exchange factor 2; rho guanine nucleotide exchange factor 2-like protein; Rho/Rac guanine nucleotide exchange factor (GEF) 2; Rho/Rac guanine nucleotide exchange factor 2; rhobin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9181

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form:
Liquid