PIMA534981
CD206 Monoclonal Antibody (CL0387), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA534981-Each-of-1 | In Stock | ₹ 47,956.38 |
PIMA534981 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,956.38
GST (18%): ₹ 8,632.148
Total Price: ₹ 56,588.528
Antigen
CD206
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P22897
Gene Symbols
Mrc1
Immunogen
Recombinant Protein corresonding to Human CD206
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
Immunohistochemistry, Western Blot
Clone
CL0387
Conjugate
Unconjugated
Gene
Mrc1
Gene Alias
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
4360
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Immunogen sequence: NEDHKRCVDA VSPSAVQTAA CNQDAESQKF RWVSESQIMS VAFKLCLGVP SKTDWVAITL YACDSKSEFQ KWECKNDTLL GIKGEDLFFN YGNRQEKNIM LYKGSGLWSR WKIYG CD206 (MSR, Mannose receptor, MRC1) is a 175 kDa transmembrane protein belonging to the group of pattern recognition receptors
- CD206 is predominantly expressed in tissue macrophages, dendritic cells, a subpopulation of endothelial cells and sperm cells
- CD206 is thought to play a role in the innate and adaptive immune response
- CD206 is also expressed on microglia and mato cells of the brain but not astrocytes or neurons
- CD206 also mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta)
- While the normal role of CD206 is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Amyloid beta deposition in Alzheimer's disease (AD)
- CD206’s gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing
- The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs)
- The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms
- CD206 has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis
- The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages
- Other diseases associated with CD206 dysfunction include leprosy and Gaucher’s Disease.
Compare Similar Items
Show Difference
Antigen: CD206
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P22897
Gene Symbols: Mrc1
Immunogen: Recombinant Protein corresonding to Human CD206
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry, Western Blot
Clone: CL0387
Conjugate: Unconjugated
Gene: Mrc1
Gene Alias: AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4360
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD206
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P22897
Gene Symbols:
Mrc1
Immunogen:
Recombinant Protein corresonding to Human CD206
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry, Western Blot
Clone:
CL0387
Conjugate:
Unconjugated
Gene:
Mrc1
Gene Alias:
AW259686; bA541I19.1; CD206; CELE_Y39A3CR.4; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; ddp-1; hMR; Human mannose receptor; macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; Mitochondrial import inner membrane translocase subunit Tim8; MMR; MR; MRC1; MRC1L1; tim-8; Y39A3CR.4
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4360
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: BRD4
Classification: Monoclonal
Concentration: 1.00 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: O60885
Gene Symbols: BRD4
Immunogen: Recombinant Protein corresonding to Human BRD4
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: CL1115
Conjugate: Unconjugated
Gene: BRD4
Gene Alias: Brd4; BRD4-NUT FUSION; Brd5; bromodomain containing 4; bromodomain-containing 4; bromodomain-containing 5; bromodomain-containing protein 4; bromodomain-containing protein 4; LOW QUALITY PROTEIN: bromodomain-containing protein 4; CAP; chromosome-associated protein; fsh-like protein; HUNK1; HUNKI; Mcap; mitotic chromosome-associated protein; Protein HUNK1; WI-11513
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23476
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
BRD4
Classification:
Monoclonal
Concentration:
1.00 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
O60885
Gene Symbols:
BRD4
Immunogen:
Recombinant Protein corresonding to Human BRD4
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
CL1115
Conjugate:
Unconjugated
Gene:
BRD4
Gene Alias:
Brd4; BRD4-NUT FUSION; Brd5; bromodomain containing 4; bromodomain-containing 4; bromodomain-containing 5; bromodomain-containing protein 4; bromodomain-containing protein 4; LOW QUALITY PROTEIN: bromodomain-containing protein 4; CAP; chromosome-associated protein; fsh-like protein; HUNK1; HUNKI; Mcap; mitotic chromosome-associated protein; Protein HUNK1; WI-11513
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23476
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: c-Kit
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P10721
Gene Symbols: KIT
Immunogen: Recombinant Protein corresonding to Human c-Kit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry, Western Blot
Clone: CL1657
Conjugate: Unconjugated
Gene: KIT
Gene Alias: belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3815
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
c-Kit
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P10721
Gene Symbols:
KIT
Immunogen:
Recombinant Protein corresonding to Human c-Kit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry, Western Blot
Clone:
CL1657
Conjugate:
Unconjugated
Gene:
KIT
Gene Alias:
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3815
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: VWF
Classification: Monoclonal
Concentration: __
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P04275
Gene Symbols: VWF
Immunogen: Recombinant Protein corresonding to Human VWF
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Immunohistochemistry, Western Blot
Clone: CL1950
Conjugate: Unconjugated
Gene: VWF
Gene Alias: 6820430P06Rik; AI551257; B130011O06Rik; C630030D09; Coagulation Factor VIII; coagulation factor VIII VWF; EMBL:CAB37852.1}; F8VWF; factor viii related antigen; von Willebrand antigen 2; von Willebrand antigen II; von Willebrand Disease (vWD); von Willebrand factor; Von Willebrand factor homolog; VWD; vwf; vwf {ECO:0000312
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7450
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
VWF
Classification:
Monoclonal
Concentration:
__
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P04275
Gene Symbols:
VWF
Immunogen:
Recombinant Protein corresonding to Human VWF
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunohistochemistry, Western Blot
Clone:
CL1950
Conjugate:
Unconjugated
Gene:
VWF
Gene Alias:
6820430P06Rik; AI551257; B130011O06Rik; C630030D09; Coagulation Factor VIII; coagulation factor VIII VWF; EMBL:CAB37852.1}; F8VWF; factor viii related antigen; von Willebrand antigen 2; von Willebrand antigen II; von Willebrand Disease (vWD); von Willebrand factor; Von Willebrand factor homolog; VWD; vwf; vwf {ECO:0000312
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7450
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid