PIMA535060

IGF1 Recombinant Rabbit Monoclonal Antibody (ARC0505), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA535060-Each-of-1 In Stock ₹ 45,646.26

PIMA535060 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

IGF1

Classification

Monoclonal

Concentration

0.35 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P05017, P05019

Gene Symbols

IGF1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 70-150 of human IGF1 (P05019)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin)

Clone

ARC0505

Conjugate

Unconjugated

Gene

IGF1

Gene Alias

C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16000, 3479

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Immunogen sequence: GFYFNKPTGY GSSSRRAPQT GIVDECCFRS CDLRRLEMYC APLKPAKSAR SVRAQRHTDM PKTQKYQPPS TNKNTKSQRR K IGF1 (Insulin-like growth factor-1) is structurally and functionally related to insulin but has a much higher growth-promoting activity
  • A variety of cellular responses are induced by IGF1, including cell proliferation, differentiation, migration, and survival
  • Further, IGF1 is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types in muscle, bone, and cartilage tissue
  • IGF1 stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regards to enhancing glucose uptake
  • In circulation, IGFs are predominantly bound to binding proteins (IGFBPs) which prolong the half-life of the IGFs and play a role in delivering them to target tissues
  • IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death
  • Moreover, mature human IGF-I is 100% homologous with bovine and porcine proteins
  • Low levels of IGF1 have been linked to Alzheimer's disease
  • IGF1 is processed from a precursor, bound by a specific receptor, and secreted
  • Defects in the IGF1 gene are a cause of insulin-like growth factor 1 deficiency and several transcript variants encoding different isoforms have been found.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA535060

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Antigen:
IGF1

Classification:
Monoclonal

Concentration:
0.35 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P05017, P05019

Gene Symbols:
IGF1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human IGF1 (P05019)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Clone:
ARC0505

Conjugate:
Unconjugated

Gene:
IGF1

Gene Alias:
C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16000, 3479

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535062

--


Antigen:
ISL1

Classification:
Monoclonal

Concentration:
0.51 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P61371, P61372, P61374

Gene Symbols:
ISL1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Islet1 (P61371)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC0511

Conjugate:
Unconjugated

Gene:
ISL1

Gene Alias:
Insulin gene enhancer protein ISL-1; insulin related protein; ISL LIM homeobox 1; Isl1; Isl-1; isl-1 homeobox; ISL1 transcription factor LIM/homeodomain (islet-1); ISL1 transcription factor, LIM/homeodomain; ISL1 transcription factor, LIM/homeodomain 1; isl-1=homeobox; Islet 1; ISLET1; islet-1; Lim-homeodomain protein Islet1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16392, 3670, 64444

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535063

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Antigen:
HES1

Classification:
Monoclonal

Concentration:
0.6 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P35428, Q04666

Gene Symbols:
HES1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 181-280 of human HES1 (Q14469)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
ARC0513

Conjugate:
Unconjugated

Gene:
HES1

Gene Alias:
BHLHB39; class B basic helix-loop-helix protein 39; FLJ20408; Hairy and enhancer of split 1; hairy and enhancer of split 1 (Drosophila); hairy and enhancer of split 1,; hairy homolog; Hairy-like; Hairy-like protein; hes family bHLH transcription factor 1; HES1; Hes-1; hHL; HL; HRY; RHL; transcription factor HES-1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15205, 29577

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535065

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Antigen:
EpCAM

Classification:
Monoclonal

Concentration:
0.58 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O55159, P16422, Q99JW5

Gene Symbols:
EPCAM

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human EpCAM (P16422)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC0521

Conjugate:
Unconjugated

Gene:
EPCAM

Gene Alias:
adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17075, 171577, 4072

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid