PIMA535126
BACE1 Recombinant Rabbit Monoclonal Antibody (ARC0696), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA535126-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA535126 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
BACE1
Classification
Monoclonal
Concentration
1.5 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P56817, P56818, P56819
Gene Symbols
BACE1
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 402-501 of human BACE1 (P56817)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
ARC0696
Conjugate
Unconjugated
Gene
BACE1
Gene Alias
APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23621, 23821, 29392
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Immunogen sequence: FYVVFDRARK RIGFAVSACH VHDEFRTAAV EGPFVTLDME DCGYNIPQTD ESTLMTIAYV MAAICALFML PLCLMVCQWR CLRCLRQQHD DFADDISLLK BACE1 (beta-secretase) is a key enzyme involved in the production of amyloid beta-peptides (Abeta) found in extracellular amyloid plaques of Alzheimer's disease (AD)
- In some cases early onset familial AD can be attributed to a "Swedish" mutation in the amyloid precursor protein (APP), which dramatically enhances the cleavage of this protein by BACE1
- This and other genetic and pathological evidence has led to therapeutic approaches that have focused on the inhibition of BACE1 and other APP-cleaving enzymes, such as gamma-secretase stuff
- APP is first cleaved by b-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99)
- The C99 fragment serves as substrate for g-secretase to generate the 4 kDa amyloid-b peptide, which is deposited in the brains of all sufferers of Alzheimer's disease
- The long-sought b-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2)
- bACE/Asp2 is a novel transmembrane aspartic protease and colocalizes with APP.
Compare Similar Items
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Antigen: BACE1
Classification: Monoclonal
Concentration: 1.5 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P56817, P56818, P56819
Gene Symbols: BACE1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 402-501 of human BACE1 (P56817)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: ARC0696
Conjugate: Unconjugated
Gene: BACE1
Gene Alias: APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23621, 23821, 29392
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
BACE1
Classification:
Monoclonal
Concentration:
1.5 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P56817, P56818, P56819
Gene Symbols:
BACE1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 402-501 of human BACE1 (P56817)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
ARC0696
Conjugate:
Unconjugated
Gene:
BACE1
Gene Alias:
APP beta-secretase; asp 2; ASP2; Aspartyl protease 2; BACE; BACE 1; BACE1; BACE-1D; BACE-I-432; Beta secretase; Beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme 1; C76936; HSPC104; hypothetical protein LOC403005; KIAA1149; Memapsin; Memapsin2; Memapsin-2; membrane-associated aspartic protease 2; protease; transmembrane aspartic proteinase Asp2; zgc:77409
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23621, 23821, 29392
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: EEF1A1
Classification: Monoclonal
Concentration: 0.55 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.: P10126, P62630, P68104
Gene Symbols: Eef1a1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human eEF1A1 (NP_0013931)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 8G4Q9
Conjugate: Unconjugated
Gene: Eef1a1
Gene Alias: CCS3; CCS-3; cervical cancer suppressor 3; CTCL tumor antigen; EE1A1; EEF-1; EEF1A; eef1a1; eEF1A-1; eef1a1.S; Eef1a2; Eef1a2l1; eef1as; eef1a-s; EF-1 alpha; EF-1 alpha2; EF1A; EF1A1; EF1a-like protein; EF1alpha; EF-1-alpha-1; EF-1-alpha-S; EF-Tu; elongation factor 1 A-1; elongation factor 1 alpha subunit; elongation factor 1-alpha 1; Elongation factor 1-alpha, somatic form; elongation factor Tu; elongation factor-1 alpha; eukaryotic elongation factor 1 A-1; eukaryotic translation elongation factor 1 alpha 1; eukaryotic translation elongation factor 1 alpha 1 S homeolog; eukaryotic translation elongation factor 1 alpha 1-like 14; eukaryotic translation elongation factor 1 alpha 2 like 1; eukaryotic translation elongation factor 1 alpha, somatic form; glucocorticoid receptor AF-1 specific elongation factor; GRAF 1EF; GRAF-1EF; HNGC:16303; LENG7; leukocyte receptor cluster (LRC) member 7; leukocyte receptor cluster member 7; prostate tumor-inducing protein 1; PTI1; SI; translation elongation factor 1 alpha 1-like 14; XELAEV_18029462mg
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13627, 171361, 1915
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
EEF1A1
Classification:
Monoclonal
Concentration:
0.55 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.:
P10126, P62630, P68104
Gene Symbols:
Eef1a1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human eEF1A1 (NP_0013931)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
8G4Q9
Conjugate:
Unconjugated
Gene:
Eef1a1
Gene Alias:
CCS3; CCS-3; cervical cancer suppressor 3; CTCL tumor antigen; EE1A1; EEF-1; EEF1A; eef1a1; eEF1A-1; eef1a1.S; Eef1a2; Eef1a2l1; eef1as; eef1a-s; EF-1 alpha; EF-1 alpha2; EF1A; EF1A1; EF1a-like protein; EF1alpha; EF-1-alpha-1; EF-1-alpha-S; EF-Tu; elongation factor 1 A-1; elongation factor 1 alpha subunit; elongation factor 1-alpha 1; Elongation factor 1-alpha, somatic form; elongation factor Tu; elongation factor-1 alpha; eukaryotic elongation factor 1 A-1; eukaryotic translation elongation factor 1 alpha 1; eukaryotic translation elongation factor 1 alpha 1 S homeolog; eukaryotic translation elongation factor 1 alpha 1-like 14; eukaryotic translation elongation factor 1 alpha 2 like 1; eukaryotic translation elongation factor 1 alpha, somatic form; glucocorticoid receptor AF-1 specific elongation factor; GRAF 1EF; GRAF-1EF; HNGC:16303; LENG7; leukocyte receptor cluster (LRC) member 7; leukocyte receptor cluster member 7; prostate tumor-inducing protein 1; PTI1; SI; translation elongation factor 1 alpha 1-like 14; XELAEV_18029462mg
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13627, 171361, 1915
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: RhoGDI
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P52565, Q5XI73, Q99PT1
Gene Symbols: ARHGDIA
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 70-150 of human RhoGDI (P52565)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: ARC0629
Conjugate: Unconjugated
Gene: ARHGDIA
Gene Alias: 5330430M07Rik; Arhgdia; arhgdia {ECO:0000312; Bles01; C87222; epididymis secretory sperm binding protein Li 47e; Gdi1; Gdi-1; GDIA1; GDP-dissociation inhibitor, aplysia RAS-related 1; HEL-S-47e; MGC117248; NPHS8; QtrA-11619; RGD:1359547}; Rho GDI 1; rho GDI 1 {ECO:0000250; Rho GDI alpha; Rho GDP dissociation inhibitor (GDI) alpha; Rho GDP dissociation inhibitor alpha; rho GDP-dissociation inhibitor 1; rho GDP-dissociation inhibitor 1 {ECO:0000250; RhoDGI; RHOGDI; Rho-GDI; Rho-GDI alpha; rho-GDI alpha {ECO:0000250; RhoGDI-1; UniProtKB:P19803}; unnamed protein product
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 192662, 360678, 396
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
RhoGDI
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P52565, Q5XI73, Q99PT1
Gene Symbols:
ARHGDIA
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human RhoGDI (P52565)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
ARC0629
Conjugate:
Unconjugated
Gene:
ARHGDIA
Gene Alias:
5330430M07Rik; Arhgdia; arhgdia {ECO:0000312; Bles01; C87222; epididymis secretory sperm binding protein Li 47e; Gdi1; Gdi-1; GDIA1; GDP-dissociation inhibitor, aplysia RAS-related 1; HEL-S-47e; MGC117248; NPHS8; QtrA-11619; RGD:1359547}; Rho GDI 1; rho GDI 1 {ECO:0000250; Rho GDI alpha; Rho GDP dissociation inhibitor (GDI) alpha; Rho GDP dissociation inhibitor alpha; rho GDP-dissociation inhibitor 1; rho GDP-dissociation inhibitor 1 {ECO:0000250; RhoDGI; RHOGDI; Rho-GDI; Rho-GDI alpha; rho-GDI alpha {ECO:0000250; RhoGDI-1; UniProtKB:P19803}; unnamed protein product
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
192662, 360678, 396
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: GSS
Classification: Monoclonal
Concentration: 0.33 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P46413, P48637, P51855
Gene Symbols: GSS
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 350-450 of human Glutathione Synthetase (GSS) (P48637)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: ARC0630
Conjugate: Unconjugated
Gene: GSS
Gene Alias: AI314904; Glutathione synthase; glutathione synthetase; GS-A/GS-B; GSH S; GSH synthetase; GSHB; GSHS; GSH-S; GSS; HEL-S-64p; HEL-S-88n; MGC14098; OTTHUMP00000030711
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14854, 25458, 2937
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
GSS
Classification:
Monoclonal
Concentration:
0.33 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P46413, P48637, P51855
Gene Symbols:
GSS
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human Glutathione Synthetase (GSS) (P48637)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
ARC0630
Conjugate:
Unconjugated
Gene:
GSS
Gene Alias:
AI314904; Glutathione synthase; glutathione synthetase; GS-A/GS-B; GSH S; GSH synthetase; GSHB; GSHS; GSH-S; GSS; HEL-S-64p; HEL-S-88n; MGC14098; OTTHUMP00000030711
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14854, 25458, 2937
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid