PIMA535201

CD18 Recombinant Rabbit Monoclonal Antibody (ARC0400), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA535201-Each-of-1 In Stock ₹ 45,646.26

PIMA535201 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

CD18

Classification

Monoclonal

Concentration

1.2 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P05107

Gene Symbols

ITGB2

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CD18 (P05107)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

ARC0400

Conjugate

Unconjugated

Gene

ITGB2

Gene Alias

2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B,

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3689

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Immunogen sequence: NFTGPGDPDS IRCDTRPQLL MRGCAADDIM DPTSLAETQE DHNGGQKQLS PQKVTLYLRP GQAAAFNVTF RRAKGYPIDL YYLMDLSYSM LDDLRNVKKL G CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes
  • CD18 can combine with integrin molecules CD11a-c to form heterodimers at the cell surface, and these heterodimers are known to participate in the process of cell adhesion as well as cell-surface mediated signaling
  • CD18 forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18)
  • In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits, and these integrins are essential for proper leukocyte migration, mediating intercellular contacts
  • Absence of CD18 leads to leukocyte adhesion deficiency-1, severe reduction of CD18 expression leads to the development of a psoriasiform skin disease
  • CD18 is also a target of Mannheimia (Pasteurella) haemolytica leukotoxin and is sufficient to mediate leukotoxin-mediated cytolysis
  • Defects in the CD18 gene are the cause of leukocyte adhesion deficiency type I (LAD1)
  • Two transcript variants encoding the CD18 protein have been identified.

Compare Similar Items

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Thermo Scientific

PIMA535201

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Antigen:
CD18

Classification:
Monoclonal

Concentration:
1.2 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P05107

Gene Symbols:
ITGB2

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CD18 (P05107)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC0400

Conjugate:
Unconjugated

Gene:
ITGB2

Gene Alias:
2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B,

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3689

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535202

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Antigen:
CD34

Classification:
Monoclonal

Concentration:
0.33 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P28906, Q64314

Gene Symbols:
Cd34

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 286-385 of human CD34 (P28906)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
5L7E2

Conjugate:
Unconjugated

Gene:
Cd34

Gene Alias:
(E3-independent) E2 ubiquitin-conjugating enzyme R1; AU040960; CD34; CD34 antigen; CD34 molecule; CDC34; cell division cycle 34; cell division cycle 34 homolog; cluster designation 34; cluster of differentiation antigen 34; E2 ubiquitin-conjugating enzyme R1; E2-CDC34; hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell marker CD34; Mucosialin; RP11-328D5.2; sialomucin protein; type 1 transmembrane protein; UBC3; UBCH3; UBE2R1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2 R1; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12490, 305081, 947

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535203

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Antigen:
CD36

Classification:
Monoclonal

Concentration:
3 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q07969, Q08857

Gene Symbols:
CD36

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human CD36/SR-B3 (P16671)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC0461

Conjugate:
Unconjugated

Gene:
CD36

Gene Alias:
adipocyte membrane protein; BDPLT10; Cd36; CD36 antigen; CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule; CD36 molecule (thrombospondin receptor); CD36 protein; CHDS7; cluster determinant 36; collagen type I receptor thrombospondin receptor; collagen type I receptor, thrombospondin receptor; FAT; FAT/CD36; fatty acid translocase; fatty acid translocase/CD36; fatty acid transport protein; glycoprotein IIIb; GP3B; GP4; GPIIIB; GPIV; I79_011940; Leukocyte differentiation antigen CD36; PAS IV; PAS4; PAS-4; PAS-4 protein; PASIV; Platelet collagen receptor; Platelet glycoprotein 4; platelet glycoprotein IV; Scarb3; scavenger receptor class B, member 3; SR-B3; Thrombospondin receptor

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12491, 29184

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535205

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Antigen:
CD154 (CD40 Ligand)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P27548, Q9Z2V2

Gene Symbols:
CD40LG

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CD40L (P29965)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC0399

Conjugate:
Unconjugated

Gene:
CD40LG

Gene Alias:
CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40L; CD40-L; Cd40lg; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21947, 84349

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid