PIMA535302
STAT3 Recombinant Rabbit Monoclonal Antibody (6W3L3), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA535302-Each-of-1 | In Stock | ₹ 46,844.10 |
PIMA535302 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,844.10
GST (18%): ₹ 8,431.938
Total Price: ₹ 55,276.038
Antigen
STAT3
Classification
Monoclonal
Concentration
0.80 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P40763, P42227, P52631
Gene Symbols
STAT3
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human STAT3 (P40763)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
6W3L3
Conjugate
Unconjugated
Gene
STAT3
Gene Alias
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20848, 25125, 6774
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Immunogen sequence: TKPPGTFLLR FSESSKEGGV TFTWVEKDIS GKTQIQSVEP YTKQQLNNMS FAEIIMGYKI MDATNILVSP LVYLYPDIPK EEAFGKYCRP ESQEHPEADP G STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
- Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
- STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
- Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
- In humans, the STAT3 gene is located on the q arm of chromosome 17
- STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
- The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
- STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
- The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
- Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
- Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.
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Antigen: STAT3
Classification: Monoclonal
Concentration: 0.80 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P40763, P42227, P52631
Gene Symbols: STAT3
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 600-700 of human STAT3 (P40763)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 6W3L3
Conjugate: Unconjugated
Gene: STAT3
Gene Alias: 1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20848, 25125, 6774
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
STAT3
Classification:
Monoclonal
Concentration:
0.80 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P40763, P42227, P52631
Gene Symbols:
STAT3
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human STAT3 (P40763)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
6W3L3
Conjugate:
Unconjugated
Gene:
STAT3
Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20848, 25125, 6774
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: E2F1
Classification: Monoclonal
Concentration: 0.4 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O09139, Q01094, Q61501
Gene Symbols: E2F1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 338-437 of human E2F1 (Q01094)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Clone: ARC0058
Conjugate: Unconjugated
Gene: E2F1
Gene Alias: E2F transcription factor 1; E2F1; E2F-1; mKIAA4009; PBR3; PRB-binding protein E2F-1; RBAP1; RBAP-1; RBBP3; RBBP-3; RBP3; Retinoblastoma-associated protein 1; retinoblastoma-binding protein 3; Transcription factor E2F1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13555, 1869, 399489
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
E2F1
Classification:
Monoclonal
Concentration:
0.4 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O09139, Q01094, Q61501
Gene Symbols:
E2F1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 338-437 of human E2F1 (Q01094)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Clone:
ARC0058
Conjugate:
Unconjugated
Gene:
E2F1
Gene Alias:
E2F transcription factor 1; E2F1; E2F-1; mKIAA4009; PBR3; PRB-binding protein E2F-1; RBAP1; RBAP-1; RBBP3; RBBP-3; RBP3; Retinoblastoma-associated protein 1; retinoblastoma-binding protein 3; Transcription factor E2F1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13555, 1869, 399489
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: RIP1
Classification: Monoclonal
Concentration: 0.4 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q13546
Gene Symbols: RIPK1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 289-490 of human RIPK1/RIP (NP_0037952)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Clone: ARC0059
Conjugate: Unconjugated
Gene: RIPK1
Gene Alias: cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8737
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
RIP1
Classification:
Monoclonal
Concentration:
0.4 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q13546
Gene Symbols:
RIPK1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 289-490 of human RIPK1/RIP (NP_0037952)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Clone:
ARC0059
Conjugate:
Unconjugated
Gene:
RIPK1
Gene Alias:
cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8737
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: CTCF
Classification: Monoclonal
Concentration: 0.4 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P49711, Q61164, Q9R1D1
Gene Symbols: CTCF
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 628-727 of human CTCF (P49711)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, ChIP sequencing (ChIP-seq), CUT&RUN, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: ARC0067
Conjugate: Unconjugated
Gene: CTCF
Gene Alias: 11 zinc finger transcriptional repressor; 11-zinc finger protein; AW108038; CCCTC-binding factor; CCCTC-binding factor (zinc finger protein); Ctcf; ctcf protein; CTCFL paralog; im:7152666; MRD21; OTTHUMP00000197610; Transcriptional repressor CTCF; Unknown (protein for IMAGE:8125283)
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10664, 13018, 83726
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CTCF
Classification:
Monoclonal
Concentration:
0.4 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P49711, Q61164, Q9R1D1
Gene Symbols:
CTCF
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 628-727 of human CTCF (P49711)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), CUT&RUN, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
ARC0067
Conjugate:
Unconjugated
Gene:
CTCF
Gene Alias:
11 zinc finger transcriptional repressor; 11-zinc finger protein; AW108038; CCCTC-binding factor; CCCTC-binding factor (zinc finger protein); Ctcf; ctcf protein; CTCFL paralog; im:7152666; MRD21; OTTHUMP00000197610; Transcriptional repressor CTCF; Unknown (protein for IMAGE:8125283)
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10664, 13018, 83726
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid