PIMA535584

ALAS1 Recombinant Rabbit Monoclonal Antibody (ARC0239), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA535584-Each-of-1 In Stock ₹ 45,646.26

PIMA535584 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

ALAS1

Classification

Monoclonal

Concentration

0.58 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P13196

Gene Symbols

ALAS1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 541-640 of human ALAS1 (P13196)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

ARC0239

Conjugate

Unconjugated

Gene

ALAS1

Gene Alias

5'-aminolevulinate synthase 1; 5-aminolevulinate synthase 1; 5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinic acid synthase 1; ALAS; ALA-S; ALAS1; Alas-1; ALAS3; ALASH; Alas-h; ALAS-N; aminolevulinate synthase H; aminolevulinate, delta-, synthase 1; aminolevulinic acid synthase 1; delta-ALA synthase 1; delta-ALA synthetase; delta-aminolevulinate synthase 1; MIG4; migration-inducing protein 4; OK/SW-cl.121; succinyl-CoA: glycine C-succinyl transferase

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

211

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Immunogen sequence: TEVCDELMSR HNIYVQAINY PTVPRGEELL RIAPTPHHTP QMMNYFLENL LVTWKQVGLE LKPHSSAECN FCRRPLHFEV MSEREKSYFS GLSKLVSAQA ALAS-1 is a nuclear-encoded mitochondrial matrix enzyme which catalyzes the condensation of glycine with succinyl-CoA to form delta-amino levulinate, CO2 and CoA
  • It regulates the first and rate-limiting step of heme biosynthetic pathway
  • It is one of the two isoforms of ALAS and is a pyridoxal-5' phosphate dependant housekeeping enzyme
  • It is ubiquitously expressed and is responsible of providing heme for cytochromes and other hemoproteins
  • ALAS1 in liver undergoes negative feedback regulation by heme
  • Transcription of ALAS1 gene is stimulated by cAMP and respiratory uncoupling whereas Phorbol esters and insulin repress ALAS1 gene expression
  • ALAS1 is suggested to be involved in reciprocal regulation of Heme biosynthesis and circadian clock suggesting a potential target for treatment of circadian disorders
  • ALAS1 gene expression is down regulated in Acute Liver failure resulting in altered heme metabolism and liver function.

Compare Similar Items

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Img

Thermo Scientific

PIMA535584

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Antigen:
ALAS1

Classification:
Monoclonal

Concentration:
0.58 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P13196

Gene Symbols:
ALAS1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 541-640 of human ALAS1 (P13196)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC0239

Conjugate:
Unconjugated

Gene:
ALAS1

Gene Alias:
5'-aminolevulinate synthase 1; 5-aminolevulinate synthase 1; 5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinic acid synthase 1; ALAS; ALA-S; ALAS1; Alas-1; ALAS3; ALASH; Alas-h; ALAS-N; aminolevulinate synthase H; aminolevulinate, delta-, synthase 1; aminolevulinic acid synthase 1; delta-ALA synthase 1; delta-ALA synthetase; delta-aminolevulinate synthase 1; MIG4; migration-inducing protein 4; OK/SW-cl.121; succinyl-CoA: glycine C-succinyl transferase

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
211

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535587

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Antigen:
Histone H3.3

Classification:
Monoclonal

Concentration:
1.22 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P84243

Gene Symbols:
H3-3A, H3-3B

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 57-136 of human Histone H33 (P84243)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC0255

Conjugate:
Unconjugated

Gene:
H3-3A

Gene Alias:
9430068D06Rik; CG5825; CG5825-PA; CG5825-PC; CG5825-PD; CG8989; dH3.3A; Dmel\CG5825; Dmel_CG5825; family 3B (H3.3B); H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3.3; H3.3 histone A; H3.3 histone B; H3.3A; H3.3A/B; H3.3B; H3.4; H3.A; H3.B; H3/g; H3-3A; H3-3B; H3B; H3F3; H3F3A; H3F3A protein; H3F3B; H3FT; H3-IX; H3L-like histone; H3t; H3-X; His3.3; His3.3A; His-3.3A; His3.3A-PA; His3.3A-PC; His3.3A-PD; His3.3B; histone; Histone cluster 3; Histone H3; histone H3 class II; Histone H3.3; histone H3.3A; Histone H3.3B; histone H3.3-like protein; MGC126886; MGC126888; PH3; PP781; similar to H3 histone, family 3A; unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3020, 3021

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535588

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Antigen:
Calnexin

Classification:
Monoclonal

Concentration:
0.55 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P27824

Gene Symbols:
CANX

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 493-592 of human Calnexin (P27824)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
ARC0648

Conjugate:
Unconjugated

Gene:
CANX

Gene Alias:
1110069N15Rik; AI988026; calmegin; calnexin; canx; canx-a; canx-b; clgn; clnx; cnx; D11Ertd153e; FLJ26570; hypothetical protein; IP90; Major histocompatibility complex class I antigen-binding protein p88; p88; P90; PP90; pp90 precursor

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
821

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535590

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Antigen:
MLH1

Classification:
Monoclonal

Concentration:
0.69 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
P40692, Q9JK91

Gene Symbols:
Mlh1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human MLH1 (NP_0002401)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
8K1T2

Conjugate:
Unconjugated

Gene:
Mlh1

Gene Alias:
1110035C23Rik; AI317206; AI325952; AI561766; COCA2; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; DNA mismatch repair protein Mlh1-like protein; FCC2; hMLH1; HNPCC; HNPCC2; I79_014127; MGC5172; mismatch repair protein 1; MLH1; MLH-1; mutL homolog 1; mutL homolog 1 (E. coli); mutL homolog 1, colon cancer, nonpolyposis type 2; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); mutL protein homolog 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17350, 4292

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid